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JournalISSN: 1362-4393

Spinal Cord 

Springer Nature
About: Spinal Cord is an academic journal published by Springer Nature. The journal publishes majorly in the area(s): Spinal cord injury & Spinal cord. It has an ISSN identifier of 1362-4393. Over the lifetime, 6178 publications have been published receiving 188914 citations.


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Journal ArticleDOI
TL;DR: The incidence of various types of fracture and fracture-dislocation and the degree of reduction achieved by postural reduction is analysed in relation to the initial and late neurological lesions.
Abstract: Six hundred and twelve patients with closed spinal injuries are described The incidence of various types of fracture and fracture-dislocation and the degree of reduction achieved by postural reduction is analysed in relation to the initial and late neurological lesions The average time that the patients were kept in bed is given for the various types of skeletal injury Only 4 patients developed late instability of the spine

2,225 citations

Journal ArticleDOI
TL;DR: International Standards for Neurological and Functional Classification of Spinal Cord Injury are published and will be used for clinical practice.
Abstract: International Standards for Neurological and Functional Classification of Spinal Cord Injury

2,062 citations

Journal ArticleDOI
TL;DR: The International Standards Booklet for Neurological and Functional Classification of Spinal Cord Injury (ISBWC) as mentioned in this paper is a standard for the classification of spinal cord injury. But it is not a classification of neurological disorders.
Abstract: The International Standards Booklet for Neurological and Functional Classification of Spinal Cord Injury

1,709 citations

Journal ArticleDOI
TL;DR: There is a need for improved registration of SCI, and publication of the findings in many parts of the world, as the data show that the reported incidence and prevalence have not changed substantially over the past 30 years.
Abstract: Incidence, prevalence and epidemiology of spinal cord injury: what learns a worldwide literature survey?

1,053 citations

Journal ArticleDOI
TL;DR: The spontaneous rate of recovery after SCI and resulting consequences for achieving statistically significant results in clinical trials are examined, based on previous data of the magnitude of spontaneous recovery afterSCI, as measured by changes in ASIA motor scores.
Abstract: The International Campaign for Cures of Spinal Cord Injury Paralysis (ICCP) supported an international panel tasked with reviewing the methodology for clinical trials in spinal cord injury (SCI), and making recommendations on the conduct of future trials. This is the first of four papers. Here, we examine the spontaneous rate of recovery after SCI and resulting consequences for achieving statistically significant results in clinical trials. We have reanalysed data from the Sygen trial to provide some of this information. Almost all people living with SCI show some recovery of motor function below the initial spinal injury level. While the spontaneous recovery of motor function in patients with motor-complete SCI is fairly limited and predictable, recovery in incomplete SCI patients (American spinal injury Association impairment scale (AIS) C and AIS D) is both more substantial and highly variable. With motor complete lesions (AIS A/AIS B) the majority of functional return is within the zone of partial preservation, and may be sufficient to reclassify the injury level to a lower spinal level. The vast majority of recovery occurs in the first 3 months, but a small amount can persist for up to 18 months or longer. Some sensory recovery occurs after SCI, on roughly the same time course as motor recovery. Based on previous data of the magnitude of spontaneous recovery after SCI, as measured by changes in ASIA motor scores, power calculations suggest that the number of subjects required to achieve a significant result from a trial declines considerably as the start of the study is delayed after SCI. Trials of treatments that are most efficacious when given soon after injury will therefore, require larger patient numbers than trials of treatments that are effective at later time points. As AIS B patients show greater spontaneous recovery than AIS A patients, the number of AIS A patients requiring to be enrolled into a trial is lower. This factor will have to be balanced against the possibility that some treatments will be more effective in incomplete patients. Trials involving motor incomplete SCI patients, or trials where an accurate assessment of AIS grade cannot be made before the start of the trial, will require large subject numbers and/or better objective assessment methods.

773 citations

Performance
Metrics
No. of papers from the Journal in previous years
YearPapers
202341
2022153
2021190
2020176
2019132
2018163