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JournalISSN: 0039-9140


About: Talanta is an academic journal. The journal publishes majorly in the area(s): Detection limit & Extraction (chemistry). It has an ISSN identifier of 0039-9140. Over the lifetime, 26443 publication(s) have been published receiving 659285 citation(s). more


Journal ArticleDOI: 10.1016/J.TALANTA.2008.05.019
15 Sep 2008-Talanta
Abstract: A review about the application of response surface methodology (RSM) in the optimization of analytical methods is presented. The theoretical principles of RSM and steps for its application are described to introduce readers to this multivariate statistical technique. Symmetrical experimental designs (three-level factorial, Box-Behnken, central composite, and Doehlert designs) are compared in terms of characteristics and efficiency. Furthermore, recent references of their uses in analytical chemistry are presented. Multiple response optimization applying desirability functions in RSM and the use of artificial neural networks for modeling are also discussed. more

3,660 Citations

Journal ArticleDOI: 10.1016/S0039-9140(02)00268-0
Badal Kumar Mandal1, Kazuo T. Suzuki1Institutions (1)
16 Aug 2002-Talanta
Abstract: This review deals with environmental origin, occurrence, episodes, and impact on human health of arsenic. Arsenic, a metalloid occurs naturally, being the 20th most abundant element in the earth's crust, and is a component of more than 245 minerals. These are mostly ores containing sulfide, along with copper, nickel, lead, cobalt, or other metals. Arsenic and its compounds are mobile in the environment. Weathering of rocks converts arsenic sulfides to arsenic trioxide, which enters the arsenic cycle as dust or by dissolution in rain, rivers, or groundwater. So, groundwater contamination by arsenic is a serious threat to mankind all over the world. It can also enter food chain causing wide spread distribution throughout the plant and animal kingdoms. However, fish, fruits, and vegetables primarily contain organic arsenic, less than 10% of the arsenic in these foods exists in the inorganic form, although the arsenic content of many foods (i.e. milk and dairy products, beef and pork, poultry, and cereals) is mainly inorganic, typically 65-75%. A few recent studies report 85-95% inorganic arsenic in rice and vegetables, which suggest more studies for standardisation. Humans are exposed to this toxic arsenic primarily from air, food, and water. Thousands and thousands of people are suffering from the toxic effects of arsenicals in many countries all over the world due to natural groundwater contamination as well as industrial effluent and drainage problems. Arsenic, being a normal component of human body is transported by the blood to different organs in the body, mainly in the form of MMA after ingestion. It causes a variety of adverse health effects to humans after acute and chronic exposures such as dermal changes (pigmentation, hyperkeratoses, and ulceration), respiratory, pulmonary, cardiovascular, gastrointestinal, hematological, hepatic, renal, neurological, developmental, reproductive, immunologic, genotoxic, mutagenetic, and carcinogenic effects. Key research studies are needed for improving arsenic risk assessment at low exposure levels urgently among all the arsenic research groups. more

Topics: Arsenic (62%), Arsenic trioxide (59%), Hyperkeratoses (53%)

2,836 Citations

Journal ArticleDOI: 10.1016/0039-9140(96)01958-3
Peter Gans1, Antonio Sabatini2, Alberto Vacca2Institutions (2)
01 Oct 1996-Talanta
Abstract: A new suite of 10 programs concerned with equilibrium constants and solution equilibria is described. The suite includes data preparation programs, pretreatment programs, equilibrium constant refinement and post-run analysis. Data preparation is facilitated by a customized data editor. The pretreatment programs include manual trial and error data fitting, speciation diagrams, end-point determination, absorbance error determination, spectral baseline corrections, factor analysis and determination of molar absorbance spectra. Equilibrium constants can be determined from potentiometric data and/or spectrophotometric data. A new data structure is also described in which information on the model and on experimental measurements are kept in separate files. more

2,574 Citations

Journal ArticleDOI: 10.1016/J.TALANTA.2005.09.037
15 Apr 2006-Talanta
Abstract: Pharmaceutical residues in the environment, and their potential toxic effects, have been recognized as one of the emerging research area in the environmental chemistry. The increasing attention, on pharmaceutical residues as potential pollutants, is due that they often have similar physico-chemical behaviour than other harmful xenobiotics which are persistent or produce adverse effects. In addition, by contrast with regulated pollutants, which often have longer environmental half-lives, its continuous introduction in the environment may make them “pseudopersistents”. Pharmaceutical residues and/or their metabolites are usually detected in the environment at trace levels, but, even that, low concentration levels (ng/L or μg/L) can induce to toxic effects. In particular, this is the case of antibiotics and steroids that cause resistance in natural bacterial populations or endocrine disruption effects. In this study, an overview of the environmental occurrence and ecological risk assessment of pharmaceutical residues is presented from literature data. Risk Quotient method (RQ) was applied as a novel approach to estimate the environmental risk of pharmaceuticals that are most frequently detected in wastewater effluents, surface waters and sediments. more

Topics: Pollutant (50%)

1,154 Citations

Journal ArticleDOI: 10.1016/S0039-9140(01)00594-X
Holger Becker, Laurie E. Locascio1Institutions (1)
11 Feb 2002-Talanta
Abstract: Since the introduction of lab-on-a-chip devices in the early 1990s, glass has been the dominant substrate material for their fabrication (J Chromatogr 593 (1992) 253; Science 261 (1993) 895) This is primarily driven by the fact that fabrication methods were well established by the semiconductor industry, and surface properties and derivatization methods were well characterized and developed by the chromatography industry among others Several material properties of glass make it a very attractive material for use in microfluidic systems; however, the cost of producing systems in glass is driving commercial producers to seek other materials Commercial manufacturers of microfluidic devices see many benefits in employing plastics that include reduced cost and simplified manufacturing procedures, particularly when compared to glass and silicon An additional benefit that is extremely attractive is the wide range of available plastic materials which allows the manufacturer to choose materials' properties suitable for their specific application In this article, we present a review of polymer-based microfluidic systems including their material properties, fabrication methods, device applications, and finally an analysis of the market that drives their development more

1,082 Citations

No. of papers from the Journal in previous years

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Journal's top 5 most impactful authors

Ru-Qin Yu

82 papers, 2.3K citations

Víctor Cerdà

74 papers, 1.7K citations

Joseph Wang

53 papers, 2.4K citations

Kate Grudpan

41 papers, 934 citations

Miguel Valcárcel

35 papers, 783 citations

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