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Showing papers in "Tetrahedron in 1978"


Journal ArticleDOI
TL;DR: In this paper, the oxidation of primary, secondary, allylic, benzylic, hindered and bicyclic alcohols with dimethyl sulfoxide (DMSO) activated by numerous electrophiles was studied: yields of carbonyls, byproducts and recovered alcohols were quantitatively determined.

1,104 citations


Journal ArticleDOI
TL;DR: In this article, 13 C NMR spectra for a variety of flavonoid glycosidcs are presented and analyzed, and evidence is presented which demonstrates that 13 C nMR spectroscopy is a valuable technique for distinguishing the sites of methylation, glycosylation and acylation in glycoiides.

858 citations


Journal ArticleDOI

397 citations



Journal ArticleDOI
TL;DR: In this paper, three simple rules are proposed that enable the prediction of the most favorable position of nucleophilic attack on 18 electron organotransition metal cations containing unsaturated hydrocarbon ligands.

251 citations


Journal ArticleDOI
TL;DR: In this article, a number of 4-substituted pyridines were found to be acylation catalysts, the most effective being 4-pyrrolidinopyridine 4 and 1,1,3,3-tetramethyl-4-(4pyridyl)guanidine 8.

217 citations


Journal ArticleDOI
TL;DR: The revised Taft scale is termed E's as discussed by the authors, which includes 44 of the original groups cited by Taft with 50 additional values obtained from literature data and has been extended to extremely hindered alkyl groups (13 in number) by measurement based on competitive reactivity.

192 citations



Journal ArticleDOI
TL;DR: In this paper, the enantiomeric purity of γ-caprolactone was confirmed within the limitations of Pirkle's chiral solvating agent, which was used for reference to determine the pheromone isolated from the black-tailed deer.

183 citations


Journal ArticleDOI
TL;DR: In this paper, the synthesis of isomeric dinucleotides using ImpU with MepU, MepC, ImpA and MepG in aqueous solution yields mixtures of (2'−5') linked compound is 6-9 times more abundant than the (3' −5')-linked compound.

157 citations



Journal ArticleDOI
TL;DR: The chemistry of β-lactams has been extensively studied in the literature as mentioned in this paper, and an attempt has been made to evaluate critically this prolific development, and an integrated form and in its proper perspective under the following headings.

Journal ArticleDOI
TL;DR: The antibacterial properties of extracts of the Caribbean gorgonian Pseudopterogorgia rigida have been shown to originate in three previously undescribed derivatives of the aromatic sesquiterpene α-curcumene.

Journal ArticleDOI
TL;DR: The NaBH4 reduction of mono-and disubstituted succinimides in the presence of hydrochloric acid leading to ω-carbinol-lactams shows a remarkable regio- and/or stereo-selectivity as discussed by the authors.

Journal ArticleDOI
TL;DR: A general method for metal-catalysed transfer reduction of nitro compounds to N-substituted hydroxylamines was developed in this article, where the reduction was performed using metal catalysts.

Journal ArticleDOI
TL;DR: The relative nucleofugicity of the nitro group in many aromatic nucleophilic substitution reactions rivals, and in some cases surpasses, that of the fluorine atom as discussed by the authors.

Journal ArticleDOI
TL;DR: In this paper, the authors define polymantanes as hydrocarbons containing at least one adamantane unit wholly or largely superimposable on the diamond lattice, and define a notation based on the four possible relative orientations of the edges of the dualist graphs.

Journal ArticleDOI
TL;DR: In this article, an operationally useful model for predicting the qualitative effect of substituents on the rates of thermal pericyclic reactions is proposed, which provides a unified interpretation of several previously unrelated experimental observations.

Journal ArticleDOI
TL;DR: In this article, the authors synthesize chalcograns in a simple manner by applying the recent technique of dianion chemistry, which is a technique that has been used in many other applications.

Journal ArticleDOI
TL;DR: Aus Aldehyden (I) erhalt man uber das Carbinol (II) die isomeren Chloride (III) and (IV) die zu den Epoxiden (V) cyclisiert and weiter mit z.B. Fluorid-Ionen zu the Allenoxiden as mentioned in this paper eliminieren.

Journal ArticleDOI
TL;DR: In this article, a revue a pour but de rassembler les travaux importants effectues dans ce domaine de 1970 a 1976 inclusivement en mettant l'accent sur la simplicite et l'immense variete d'application of cette reaction.

Journal ArticleDOI
TL;DR: In this paper, 11 sesquiterpene hydrocarbons from S. mayi were identified or structurally elucidated, including four 4,7-aromadendranediols.

Journal ArticleDOI
TL;DR: In this paper, the fundamental influence of cations in nucleophilic additions to carbonyl compounds is discussed in terms of either ionic complexation or ionic association with the nucleophile, and an experimental criterion is proposed to determine which factor controls the reactivity based on the kinetic effects of cryptand or crown-ether addition.



Journal ArticleDOI
TL;DR: In this paper, the positions of a series of trans-1,2-disubstituted cyclohexanes containing etectronegative substituents have been determined experimentally by NMR, and calculated theoretically by classical means.

Journal ArticleDOI
TL;DR: In this paper, a new, practical, synthesis of β-ketophosphonates relying on the conversion of the organolithium reagent from a dialkyl methylphosphonate into the corresponding organocopper reagent, and its reaction with acyl chlorides is described.

Journal ArticleDOI
Robert Bucourt1, R. Heymes1, Lutz A1, L. Penasse1, J. Perronnet1 
TL;DR: In this article, the synthesis of 2-(2-amino-4-thiazolyl) 2-(hydroxy or alkoxy)-imino acetic acid derivatives, with the anti (E) and syn (Z) configurations, is described.

Journal ArticleDOI
TL;DR: In this article, the structure of the lithium and potassium salts of φSCH 3, φSOCH 2 Li, φ SO CH 2 Li, and φ SCH 2 − M + was studied by 13 C NMR in different solvents, and the results showed that the metalated carbon is nearly pyramidal in and nearly planar in

Journal ArticleDOI
TL;DR: In this paper, the preparation of thirteen halo- and methyl-substituted 3,5-cyclohexadiene-1, 2-diol-1'carboxylic acids from microbial oxidation of the corresponding benzoic acids is reported.