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Showing papers in "Tetrahedron Letters in 2005"


Journal ArticleDOI
TL;DR: In this paper, a simple, inexpensive and efficient one-pot synthesis of 1,4-dihydropyridine derivatives at room temperature using catalytic amount of iodine was reported with excellent product yields.

297 citations


Journal ArticleDOI
TL;DR: The use of molecular iodine as the catalyst for a one-pot synthesis of quinoxaline derivatives at room temperature was reported in this article, where it was shown that molecular iodine can be used as a catalyst for any onepot synthesis.

249 citations


Journal ArticleDOI
TL;DR: In this paper, a simple and convenient procedure for the synthesis of aryl-14 H -dibenzo[ a. j ]xanthenes was described through a one-pot condensation of β-naphthol with aryls aldehydes in the presence of sulfamic acid as the catalyst in a solvent-free media using both conventional heating and microwave irradiation.

204 citations


Journal ArticleDOI
TL;DR: In this article, the condensation of various aromatic and heteroaromatic aldehydes with active methylene compounds like malononitrile, e.g., barbituric acids, Meldrum's acid, dimedone and pyrazolone is described.

190 citations


Journal ArticleDOI
Songnian Lin1, Lihu Yang1
TL;DR: In this paper, a direct one-step synthesis of various benzimidazoles from phenylenediamines and aldehydes using air as the oxidant is described.

190 citations


Journal ArticleDOI
TL;DR: In this article, various biologically important quinoxaline derivatives were efficiently synthesized in excellent yields using inexpensive, nontoxic, and readily available bench top chemical, iodine in catalytic amount (10 moles).

183 citations


Journal ArticleDOI
TL;DR: KAl(SO4)2·12H2O was found to catalyze efficiently a one-pot three-component cyclocondensation of isatoic anhydride and primary amines or ammonia sources such as NH4 2CO3, NH4OAc and NH4Cl with aromatic aldehydes under mild conditions to afford the corresponding mono- and disubstituted 2,3-dihydroquinazolin-4(1H)-ones in good yields as mentioned in this paper.

181 citations


Journal ArticleDOI
TL;DR: A water-soluble ruthenium-based olefin metathesis catalyst supported by a poly(ethylene glycol) conjugated N-heterocyclic carbene ligand is reported in this article.

173 citations


Journal ArticleDOI
TL;DR: In this paper, the electrophilic α-alkylation of ketones with alcohols was accomplished by a [Ru(DMSO) 4 ]Cl 2 catalyzed process, water being the only wasted material.

167 citations


Journal ArticleDOI
TL;DR: In this paper, a new fluorescent chemosensor for Hg 2+ based on a dansyl amide-armed calix[4]-aza-crown was reported.

161 citations


Journal ArticleDOI
TL;DR: Michael reaction of indoles with unsaturated ketones has been accomplished in the presence of catalytic amount of iodine under solvent-free condition.

Journal ArticleDOI
TL;DR: Highly efficient one-pot synthesis of 1,2, 3-triazole-linked glycoconjugates was presented involving a Cu(I) catalyzed 1,3-dipolar cycloaddition as the key step, offering a convenient route to prepare neoglycoconjugate derived from unprotected saccharides or peracetylated saccharide.

Journal ArticleDOI
TL;DR: In this paper, a simple, efficient and practical procedure for the Biginelli reaction using strontium(II) triflate [Sr(OTf) 2 ] as a novel catalyst is described under solvent-free conditions in high yields.

Journal ArticleDOI
TL;DR: An efficient two-step procedure for the deprotection of pinacolyl organoboronate esters is described in this article, where the trifluoroborates with either inorganic base or trimethylsilyl chloride and water are treated.

Journal ArticleDOI
TL;DR: In this paper, Amino-aryl ketones undergo smooth condensation with α-methylene ketones in the presence of sulfamic acid (NH2SO3H) under mild reaction conditions to afford the corresponding polysubstituted quinolines in excellent yields.

Journal ArticleDOI
TL;DR: This method permits direct one-step access to precursors of radiolabeled BTA and BTA-2 and their 6-methoxy analogues, used for in vivo imaging of β-amyloid plaques with positron emission tomography (PET).

Journal ArticleDOI
TL;DR: In this article, 2-Aminoaryl ketones undergo condensation with α-methylene ketones in the presence of a catalytic amount of Y(OTf)3 at room temperature under mild conditions to afford the corresponding polysubstituted quinolines in excellent yields.

Journal ArticleDOI
TL;DR: In this paper, the solvent-free acylation of alcohols and phenols with acyl chlorides using ZnO as a catalyst is described and the remarkable selectivity under mild and neutral conditions, and recyclability of the catalyst, are advantages.

Journal ArticleDOI
TL;DR: Boric acid efficiently catalyzes the conjugate addition of aliphatic amines to α,β-unsaturated compounds to produce β-amino compounds, with great alacrity and excellent yields, in water under mild conditions as mentioned in this paper.

Journal ArticleDOI
TL;DR: In this paper, the authors used Grubbs' catalyst or a ruthenium p-cymene complex without the presence of an added oxidant to achieve the oxidation of alcohols.

Journal ArticleDOI
TL;DR: In this paper, the reactions of alkyl nitriles, acetyl chloride, aldehydes and simple ketones were studied for the one-pot synthesis of β-acetamido carbonyl compounds.

Journal ArticleDOI
TL;DR: In this article, 2-Aminobenzyl alcohol reacted with 2-equiv amount of ketones under the influence of [IrCl(cod)] 2 or IrCl 3 and KOH without any solvent, giving the corresponding quinoline derivatives in good yields.

Journal ArticleDOI
TL;DR: In this article, a microwave-promoted one-pot, two-step reaction sequence combining anthranilic acids, carboxylic acids, and amines was proposed for 2,3-disubstituted 3 H -quinazolin-4-ones.

Journal ArticleDOI
TL;DR: In this paper, a general Cu-catalyzed synthesis of (hetero)aromatic nitriles from the corresponding aryl bromides and potassium hexacyanoferrate(II) is described.

Journal ArticleDOI
TL;DR: In this article, a straightforward and efficient method for the regioselective synthesis of functionalized 1,4 disubstituted [1,2,3]-triazoles, from terminal alkynes and azides, has been established utilizing Cu(0) as the source of the catalytic species.

Journal ArticleDOI
TL;DR: In this article, Pd-catalyzed homo-and cross-couplings of boronic acids and aryl halides were successfully carried out both in aqueous media under high-intensity ultrasound (US) and in DME under microwave (MW).

Journal ArticleDOI
TL;DR: A straightforward and general method for α-aminonitriles by combining aldehydes or ketones, amines, and trimethylsilyl cyanides in the presence of a catalytic amount of molecular iodine at room temperature was developed in this article.

Journal ArticleDOI
TL;DR: In this article, the 2- or 2-6-position of aromatic aldehydes were directly and selectively arylated with aryl chlorides or bromides in the presence of a catalytic system.

Journal ArticleDOI
TL;DR: In this paper, D-t-BPF was used for the cross-coupling of NH2-unprotected hetero-aryl chlorides with phenylboronic acid.

Journal ArticleDOI
TL;DR: In this article, a simple synthesis of substituted pyrroles using bismuth nitrate-catalyzed modified Paal-Knorr method has been accomplished with an excellent yield.