Showing papers in "Tetrahedron Letters in 2017"

TL;DR: In the past two decades, significant progress has been made to the development of efficient methods for the construction of gem-difluoroalkenes and useful reactions involving the cleavage of CF bond as mentioned in this paper.

TL;DR: A significant number of reactions have appeared in the literature regarding cross dehydrogenative coupling (CDC) reactions over the years as mentioned in this paper, and a review aims to cover the advances in the area of C C C bond formations via CDC reactions in the last six years (2011-2016).

TL;DR: Sugonyl hydrazides are widely utilized in organic synthesis, but it is only in recent years that they have emerged as powerful sulfonyl sources, providing alternative approaches to the preparation of sulfones and sulfonamides.

TL;DR: A facile procedure was applied to successfully synthesize novel Pd nanoparticles immobilized on triethanolamine-functionalized magnetic nanoparticles [Fe 3 O 4 /IL/Pd] as mentioned in this paper.

TL;DR: Transition-metal-catalyzed electrochemical CH functionalization has emerged as attractive tools for organic synthesis as mentioned in this paper, which provides a practical and environmentally benign procedure for CH functionalisation.

TL;DR: In this paper, a simple and efficient method for the synthesis of four-component 1,4-dihydropyridines of various aldehydes, β-ketoesters and ammonium carbonate catalyzed by sulfated polyborate with high yields under a solvent free condition at 90°C is described.

TL;DR: The reversible recognition process of HL to Al 3+ will make HL could be used circularly and repeatedly in practical applications by addition of Na 2 EDTA.

TL;DR: In this paper, a pyrene based chemosensor was designed and synthesized, which was tested with a variety of metal ions and exhibited high colorimetric selectivities for Cu 2+ and Fe 3+ over other ions.

TL;DR: The use of γ-valerolactone (GVL) and N -formylmorpholine (NFM) as DMF substitutes in polystyrene based SPPS is reported.

TL;DR: Cell imaging investigations indicate that probe 1 is cell permeable with low toxicity to MCF-7 cells, and applicable to detect Hg2+ ions in living MCF -7 cells.

TL;DR: In this paper, a review summarises the applications of heteroatom substituted donor-acceptor cyclopropanes in the total synthesis of natural products, including cycloaddition, rearrangement and cascade reactions.

TL;DR: Development of a new biaryl stapling technique for complex peptides, 18F radiofluorine introduction and diversity oriented post synthetic applications on bio-active cyclopeptides like valinomycin and aureobasidin are additional highlights which underscores the vast potential of late stage C H activation reactions in peptide based therapeutics research.

TL;DR: Wang et al. as mentioned in this paper constructed a turn-on fluorescent probe HBTM for N 2 H 4 detection based on ESIPT and ICT mechanism by incorporating the methyl dicyanvinyl group to 2-(2′-hydroxylphenyl) benzothiazole (HBT) fluorophore.

TL;DR: An efficient and environmentally benign protocol for a three-component Kabachnik-Fields reaction of aldehydes, amines, and diethyl phosphite catalyzed by sulfated polyborate has been described to afford α-amino phosphonates under solvent-free reaction conditions as discussed by the authors.

TL;DR: In this article, a rapid and highly efficient methodology for the synthesis of 3-methyl-4-(hetero)arylmethylene isoxazole-5(4H)-ones has been developed using sulfated polyborate as a catalyst.

TL;DR: Two new cyclic pentapeptide and three new linear peptides showed evident antiviral activity against herpes simplex virus type 1 (HSV-1) with IC50 values of 9.5 and 19.8 µM under their non-cytotoxic concentrations against a Vero cell line, respectively.

TL;DR: In this article, a simple Schiff base CTS, synthesized between 2-hydroxy-1-naphthaldehyde and 2-benzylthio-ethanamine, was found to be a good turn-on fluorescence probe for the detection of Zn 2+, due to the restriction of the rotation of the bond between C N and naphthalene ring and/or the blocking of the photo-induced electron transfer (PET) mechanism of the nitrogen atom.

TL;DR: Results demonstrated that this compound was antioxidant and inhibitor of the AChE activity, being a promising therapeutic agent for the treatment of Alzheimer’s disease and other neurodegenerative disorders.

TL;DR: The pentafluorosulfanyl (SF5) group has made it renowned as a "super trifluoromethyl (CF3) group".

TL;DR: In this article, a green and facile procedure has been developed for the synthesis of Cu 2 O nanoparticles within a very short reaction time using banana pulp extract as a reducing agent, and the synthesized nanoparticles are well characterized by SEM (Scanning Electron Microscope), TEM (Transmission Electron microscscope) and powder XRD (X-ray Diffraction) methods.

TL;DR: In this article, an expedient direct and regioselective thiocyanation of phenols, anilines and heterocycles is described, which is realized via the direct C H functionalization under transition metal free conditions at ambient temperature in excellent yields.

TL;DR: In this paper, a series of N-methyl morpholine (Nmm) based ionic liquids with 1,2-propanediol group were synthesized and used as catalysts for Knoevenagel condensation at room temperature in water.

TL;DR: In this article, a one-pot process for hydrodeoxygenation (HDO) of phenolic derivatives to their corresponding arenes was developed, which provided a facile route to upgrading bio-oil.

TL;DR: In this paper, a simple and straightforward approach to the synthesis of 1,8-dioxo-octahydroxanthenes, 14-phenyl-14H-dibenzo[a,j]xanthene and tetrahydrobenzoxanthene-11-ones under solvent-free conditions using sulfated polyborate as a highly efficient catalyst.

TL;DR: A simple, fast and inexpensive protocol for the oxidative coupling of thiols employing a stoichiometric amount of DMSO and iodine as the catalyst and various aromatic disulfides were obtained in good to excellent yields.

TL;DR: In this article, a mild, efficient, and environmentally benign protocol for a three-component Strecker reaction of aldehydes or ketones, amines, and trimethylsilyl cyanide catalyzed by sulfated polyborate has been described to afford α-aminonitriles under solvent-free reaction conditions.

TL;DR: In this article, a review of chiral ligands that work efficiently for cyclic and acyclic enones and demonstrate the wide applicability of Michael acceptors is presented.

TL;DR: In this article, the aqueous leaves extract of Thymbra spicata was utilized as a reducing and capping agent, and copper oxide nanoparticles (NPs) were synthesized.

TL;DR: In this paper, the authors provide an overview of recent progress on n-type organic semiconductors for application in organic thin film transistors (OTFTs) with an emphasis on molecular design.

TL;DR: The chiral Bronsted acid catalyzed enantioselective 1,2-addition of thiols to in situ generated ketimines, derived from 3-hydroxyisoindolinones, has been studied and has been converted to a known non-nucleoside HIV-1 reverse transcriptase inhibitor and a 1,3-thiazine derivative.