Showing papers in "Tetrahedron Letters in 2018"

TL;DR: Recent advances in the strategy of intramolecularly distal migration of functional groups which has been efficiently applied in the radical-mediated difunctionalization of unactivated alkenes are summarized.

TL;DR: In this article, a review of recent advances in catalytic asymmetric difunctionalization of conjugated dienes based on different metals has been presented, and the authors also introduce unique phenomena that include reversal of regio- and diastereoselectivity.

TL;DR: This digest/tutorial will give an overview of how to make efficient use of the existing pKa data.

TL;DR: In this paper, the authors highlight the design and synthesis of these versatile reagents, and their applications as precursors for transition-metal-containing 1,4-dipoles in dipolar cyclizations and related cascade reactions.

TL;DR: Geminal bis(boron) compounds have recently emerged as valuable building blocks for the synthesis of molecules with structural diversity and can be engaged in several kinds of transformations.

TL;DR: In this article, the authors highlight reported transformations that utilize alkoxy radicals in a photocatalytic fashion, in particular, underline novel catalytic platforms which they anticipate will find broad application in the near future.

TL;DR: Arylsulfonium intermediates are versatile arylation reagents for the synthesis of functional molecules as discussed by the authors, and the recent advances on the transition metal-mediated or -free -arylation using the stable aryl sulfonium salts or the metastable aryls sulfuronium intermediate are discussed in detail.

TL;DR: In this article, the authors mainly focus on recent progress on C-H functionalization reactions of aryl sulfoxides via [3,3] sigmatropic rearrangement of sulfonium-tethered intermediates.

TL;DR: In this paper, a visible light photoredox-catalyzed C-3 phosphorylation of quinoxalin-2(1H)-ones with diphenylphosphine oxide has been developed.

TL;DR: This work will focus on the advancements made so far by the use of various noncovalent interactions in Ir-catalyzed borylations.

TL;DR: A comprehensive survey of the recent new synthetic approaches to functionalized isoxazoles, with particular focus on the last three years with regard to the following reaction types: (1) 1,3-dipolar cycloaddition, (2) condensation, (3) cycloisomerization, and (4) direct functionalization.

TL;DR: The chemoselective semihydrogenation of alkynes to alkenes is one of the most important reactions in synthetic organic chemistry and a multitude of innovative catalytic methods have been developed to address the selective hydrogenation of alkynes as discussed by the authors.

TL;DR: In this article, the authors highlight the recent notable advances in homogeneous transfer hydrogenation using transition metal complexes, especially in direction to establish practical greener processes by upgrading the catalyst performance or by expanding the scope of reducible functional groups.

TL;DR: In this paper, the significance of this young but burgeoning field was emphasized with the help of these latest examples, and some recent developments in the field of artificial switchable catalysis achieved during the last couple of years.

TL;DR: Functional gels fabricated from supramolecular host–guest interactions exhibit outstanding characteristics including stimuli-responsiveness, self-healing and adaptability.

TL;DR: In this article, a simple method was developed for the synthesis of 3-aryl quinoxalin-2-one derivatives through an oxidative cross-coupling of arylboronic acids with quino-alin-1-ones using a readily available oxidant Mn(III) acetate dihydrate.

TL;DR: The recent progress made on transformations involving the reactions between aryne intermediates and organosulfur compounds has been reviewed in this paper, which has enabled the diversity-oriented synthesis of unique aromatic organo-sulfurs that were once difficult to prepare by the conventional methods, paving the way for the development of molecules that are beneficial across numerous disciplines, including pharmaceutical science and materials science.

TL;DR: The state of asymmetric photocatalysis is exceptionally promising, as chemists from different fields and backgrounds have converged to solve a longstanding issue: stereocontrol in photochemistry.

TL;DR: In this paper, a recent breakthrough on the copper-catalyzed asymmetric aminotrifluoromethylation reaction was reported, which was the first step in the development of a catalyzed version of the reaction.

TL;DR: The transition-metal-catalyzed reaction of diazo compounds with arenes or heteroarenes is an efficient and straightforward approach to functionalize aromatic compounds.

TL;DR: Chitosan-supported copper (chit@copper) based heterogeneous catalysts have been explored for A3-coupling and decarboxylative A3 coupling as mentioned in this paper.

TL;DR: In this paper, the authors present a review of the recent achievements in this regard especially using Ni, Co and Cu as first row transition metals for direct C(sp3) H bond functionalization.

TL;DR: A brief history of the quest for highly distorted amides and a collection of recent studies on catalytic transformations of designed amides can be found in this article, where the focus is on the catalytic transformation of amides with moderate distortion or reduced resonance stabilization.

TL;DR: A brief account of indole based antibacterial small molecules which have been either synthesized in the laboratory or isolated from natural sources and provide intriguing potential leads in the antibiotic drug discovery research are presented.

TL;DR: In this article, the photoredox-catalyzed C(sp2)-N coupling reactions, including Ullmann type C-N coupling (C-X/N-H type coupling), redox neutral C−N coupling, and oxidative C−n coupling, have been summarized.

TL;DR: In this paper, two new 3,4-dihydronaphthalen-(2H)-1-one (1-tetralone) derivatives, aspvanicin A (1) and its epimer aspvicin B (2), as well as several known cryptic metabolites were obtained from the ethyl acetate extract of the co-culture of the endophytic fungus Aspergillus versicolor KU258497 with the bacterium Bacillus subtilis 168 trpC2 on solid rice medium.

TL;DR: A brief overview of the recent advances in mechanochemical C-H functionalization reactions can be found in this article, where the authors aim to provide a brief overview on the recent developments in mechanochemically C−H functionalisation reactions.

TL;DR: In terms of industrial application, phosphine-mediated reactions have received much attention when compared to the catalytic versions for the synthesis of a variety of structurally diverse organic frameworks.

TL;DR: In this article, a pyrene-based receptor bearing benzothiazole was synthesized as a good turn-on fluorescent sensor for the recognition of Zn2+ in EtOH-HEPES (65:35, v/v, pH = 7.20), which might be attributed to the photoinduced electron transfer mechanism.

TL;DR: The methods reported mainly since 2014 are discussed, since the latest review on 1,2-cis-glycosylation was published at that time as discussed by the authors, and the updated mechanisms for SN2-SN1 borderlines in β-mannosylations are also discussed.