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Showing papers in "The American Journal of Gastroenterology in 2007"


Journal ArticleDOI
TL;DR: Whether to test for H. pylori in patients with functional dyspepsia, gastroesophageal reflux disease (GERD), patients taking nonsteroidal antiinflammatory drugs, with iron deficiency anemia, or who are at greater risk of developing gastric cancer remains controversial.

1,333 citations



BookDOI
TL;DR: The structural similarities and functional differences between regions may have an evolutionary basis and the physiological control of enteric neurons and development of function is studied.

1,131 citations


Journal ArticleDOI
TL;DR: ERCP remains the endoscopic procedure that carries a high risk for morbidity and mortality, and complications continue to occur at a relatively consistent rate.

937 citations


Journal ArticleDOI
TL;DR: The scoring system with abdominal ultrasonography could provide accurate information about hepatic steatosis, visceral obesity, and the metabolic syndrome in apparently healthy people who do not consume alcohol.

672 citations


Journal ArticleDOI
TL;DR: There is an association between acid suppression and an increased risk of enteric infection and further prospective studies on patients taking long-term acid suppression are needed to establish whether this association is causal.

584 citations


Journal ArticleDOI
TL;DR: Elevated serum IgG4 levels are characteristic of AIP, however, mild (<2-fold) elevations in serum Igg4 are seen in up to 10% of subjects without AIP including pancreaticcancer and cannot be used alone to distinguish AIP from pancreatic cancer.

463 citations


Journal ArticleDOI
TL;DR: Who performs the procedure can be more important than age and gender in predicting adenomas at colonoscopy, and the need to measure adenoma detection rates in the continuous quality improvement process and to report them to endoscopists is underscored.

412 citations


Journal ArticleDOI
TL;DR: FibroTest and FibroScan have excellent utility for the identification of HCV-related cirrhosis, but lesser accuracy for earlier stages, and refinements are necessary before these tests can replace liver biopsy.

382 citations


Journal ArticleDOI
TL;DR: FC cannot be recommended as a screening test for CRC in the general population and appeared to offer a good diagnostic precision in distinguishing IBD from non-IBD diagnoses, with higher precision at a cutoff level of 100 μg/g.

372 citations


Journal ArticleDOI
TL;DR: Bifidobacterium infantis 35624 showed significant improvement in the composite score for abdominal pain/discomfort, bloating/distention, and/or bowel movement difficulty compared with placebo in two appropriately designed studies; there is inadequate data to comment on the efficacy of other probiotics.

Journal ArticleDOI
TL;DR: There is marked variation in the quality of the Web sites containing information on Crohn's disease and ulcerative colitis, with many Web sites suffered from poor quality but there were five high-scoring Web sites.

Journal ArticleDOI
TL;DR: Guidelines for esophageal reflux testing are developed under the auspices of the American College of Gastroenterology and its Practice Parameters Committee and approved by the Board of Trustees.

Journal ArticleDOI
TL;DR: A new prognostic model was developed to predict progression of PSC, which may be useful in timing of liver transplantation, and a persistent bilirubin elevation for longer than 3 months from the time of diagnosis could be identified as a novel marker correlating with a poor outcome.

Journal ArticleDOI
TL;DR: Overall, an overview is provided that the coagulation system represents an important, though previously underestimated, component of IBD pathogenesis, and may be a possible target for therapeutic intervention.

Journal ArticleDOI
TL;DR: Whereas there are a number of plausible mechanisms whereby GERD might contribute to the accumulation of eosinophils in the esophageal epithelium, it seems prudent to recommend a clinical trial of proton pump inhibitor (PPI) therapy even when the diagnosis of eOSinophilic esophagitis seems clear-cut.

Journal ArticleDOI
TL;DR: A significant synergy between cigarette smoking, diabetes mellitus, heavy alcohol consumption, and family history of pancreatic cancer, respectively, suggests a common pathway for carcinogenesis of the pancreas.

Journal ArticleDOI
TL;DR: A set of guidelines for the diagnonis and management of patients with neoplastic pancreatic cysts is proposed based on published data backed by an analysis of the quality of the data and designed to address the most frequent and important clinical scenarios.

Journal ArticleDOI
TL;DR: The yield of clinically important findings on CE is 53% and is greater in patients with obscure-overt than obscure-occult GI bleeding, and compared with pre-CE, patients had clinical improvement post-CE in medical interventions for OGIB.

Journal ArticleDOI
TL;DR: Antisecretory agent or nitrate treatment is associated with reduced UGIB RR in patients taking NSAID or aspirin, and protection was not apparent in patientsTaking anticoagulants.

Journal ArticleDOI
TL;DR: An imbalance in consumption of fatty acids, vegetables, and fruits is associated with increased risks for CD among Canadian children and a higher ratio of LCN-ω-3/ω-6 fatty acids was significantly associated with lower risks forCD.

Journal ArticleDOI
TL;DR: Baseline ferritin levels were associated with body iron stores and iron depletion produced a significantly larger decrease in insulin resistance than nutritional counseling alone, independent of changes in BMI, baseline HOMA-R, and the presence of the metabolic syndrome.

Journal ArticleDOI
TL;DR: Nonalcoholic fatty liver disease is associated with the metabolic syndrome rather than excess adipose tissue in severe obesity and insulin resistance is higher in subjects with NASH versus those with simple fatty liver.

Journal ArticleDOI
TL;DR: Greater understanding of the biology of fibrostenosis is likely to yield significant advances in the ability to care for patients with stricturing CD, and potential dividends include identification of novel therapeutic targets and biomarkers useful for prognostication and therapeutic monitoring.

Journal ArticleDOI
TL;DR: This study demonstrates that an active case-finding strategy in the primary care setting is an effective means to improve the diagnostic rate of CD in North America.

Journal ArticleDOI
TL;DR: Predictors of adherence differed markedly between genders, although obstacles such as medication cost were relevant for both men and women.

Journal ArticleDOI
TL;DR: Suggested consensus indications for resection identify all patients with malignancy; however, their specificity is low and in the short term it would be safe to follow patients without these features.

Journal ArticleDOI
TL;DR: Dual endoscopic therapy proved significantly superior to epinephrine injection alone, but had no advantage over thermal or mechanical monotherapy in improving the outcome of patients with high-risk peptic ulcer bleeding.

Journal ArticleDOI
TL;DR: Midesophageal biopsies from normal-appearing mucosa should be obtained in all patients with unexplained solid food dysphagia; this may diagnose EE in about one in 10 cases.

Journal ArticleDOI
TL;DR: Second Annual Snowbird Conference on Clinical Management of Inflammatory Bowel Diseases and Intestinal Failure March 9–12, 2006.