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Showing papers in "The American Journal of Gastroenterology in 2009"


Journal ArticleDOI
TL;DR: This document is the first update of the American College of Gastroenterology (ACG) colorectal cancer screening recommendations since 2000, and it is recognized that colonoscopy is not available in every clinical setting because of economic limitations.

1,409 citations


Journal ArticleDOI
TL;DR: These guidelines were developed under the auspices of the American College of Gastroenterology by a committee of experts in the field, reviewed by its Practice Parameters Committee, and approved by the Board of Trustees to be considered valid at the time of production based on the data available.

712 citations


Journal ArticleDOI
TL;DR: A variable but relevant proportion of Crohn's disease patients on long-term infliximab treatment lose response, and this may be interpreted in two different but compatible ways: a positive view, highlighting that inflIXimab therapy is relatively durable, with the majority of patients predicted to continue inflixIMab treatment at least during the first year.

588 citations


Journal ArticleDOI
TL;DR: Over the past decade, there has been a progressive change in the overall picture of GI events leading to hospitalization, with a clear decreasing trend in upper GI events and a significant increase in lower GI events, causing the rates of these two GI complications to converge.

507 citations


Journal ArticleDOI
TL;DR: This is the first pediatric, randomized, placebo-controlled, double-blind trial that suggests the efficacy and safety of a highly concentrated mixture of probiotic bacterial strains (VSL#3) in active UC and demonstrates its role in maintenance of remission.

453 citations


Journal ArticleDOI
TL;DR: Subjects with NAFLD and elevated ALT levels are at an increased risk of developing diabetes and the MS, and this may be because of the presence of associated metabolic risk factors.

405 citations


Journal ArticleDOI
TL;DR: Patient- related factors are as important as procedure-related factors in determining high-risk predictors for post-ERCP overall complications and pancreatitis, however, the risk factors for asymptomatic hyperamylasemia may be mostly procedure related.

402 citations


Journal ArticleDOI
TL;DR: Patients with liver disease have a substantially increased risk of venous thromboembolism, and those with known malignancy have a slightly higher relative risk.

386 citations


Journal ArticleDOI
TL;DR: The consensus statements that comprise the Definition of GERD in the Pediatric Population were developed through a rigorous process and are intended to be used for the development of future clinical practice guidelines and as a basis for clinical trials.

379 citations


Journal ArticleDOI
TL;DR: A large subset of IBS patients shows gender-dependent mucosal infiltration of immunocytes that correlates with abdominal bloating and dysmotility-like dyspepsia, and provides the rationale for considering immune mechanisms as a pathophysiological component in a subset ofIBS patients.

323 citations


Journal ArticleDOI
TL;DR: Subsequent control of HTG with dietary restrictions, antihyperlipidemic agents, and even regular apheresis has been shown anecdotally in case series to prevent future episodes of AP, but large multicenter studies are needed to optimize future management guidelines for patients with HTGP.

Journal ArticleDOI
TL;DR: ST appears to be better than TT in the eradication of H. pylori, but further trials are needed in other European countries and North America before it can be recommended as a first-line treatment.

Journal ArticleDOI
TL;DR: The hypothesis that GS and post-infectious irritable bowel syndrome (IBS) provide two triggers that can explain at least part of the spectrum that constitutes IBS is discussed, further advancing an understanding of the role of mucosal responses to luminal factors in FBDs.

Journal ArticleDOI
TL;DR: Pediatric UC was characterized by widespread localization at diagnosis and a high rate of disease extension, which was influenced by disease extension and was associated with the presence of EIMS at diagnosis.

Journal ArticleDOI
TL;DR: In this group of patients, a substantial number of patients developed chronic pancreatitis in a short period of time after surviving a second attack of acute pancreatitis, and smoking significantly enhanced the risk of progression from acute to chronic alcoholic pancreatitis.

Journal ArticleDOI
TL;DR: The relative prevalence of fundic gland polyps in this population was much higher than that reported earlier, most likely because of the widespread use of proton pump inhibitors.

Journal ArticleDOI
TL;DR: This population-based IBD study showed high recurrence rates in the first year, and small bowel localization, stricturing disease, and young age were predictive for disease recurrence.

Journal ArticleDOI
TL;DR: In this second major US series, this study highlights the presence of vascular complications in a subset of patients with AIP and confirms several findings previously reported in AIP.

Journal ArticleDOI
TL;DR: Management recommendations are divided according to the status, compensated or decompensated, of the cirrhotic patient, with a separate section for the screening, diagnosis, and management of hepatocellular carcinoma (HCC), as this applies to patients with both compensated and decompensate cirrhosis.

Journal ArticleDOI
TL;DR: RF ablation is superior to PEI in the treatment of small HCC with respect to overall survival, 1, 2, and 3 years survival rates, 1-2, 2- and 3 cancer-free Survival rates, and tumor response.

Journal ArticleDOI
TL;DR: The incidence of clinically relevant findings at first screening is high with asymptomatic cancer in 7% and premalignant IPMN-like lesions in 16% in the series.

Journal ArticleDOI
TL;DR: A systematic review and meta-analysis of randomized controlled trials to estimate the efficacy of all available 5-HT agents in IBS found alosetron, cilansetrons, and tegaserod are all effective in the treatment of IBS.

Journal ArticleDOI
TL;DR: The BISAP score represents a simple way to identify patients at risk of increased mortality and the development of intermediate markers of severity within 24 h of presentation and can be utilized to improve clinical care and facilitate enrollment in clinical trials.

Journal ArticleDOI
TL;DR: Purine analogs are more effective than placebo in preventing both clinical and endoscopic postoperative recurrence in CD, but they are associated with a higher rate of adverse events leading to drug withdrawal.

Journal ArticleDOI
TL;DR: Understanding the mechanism for immunoglobulin transfer will help to understand how to minimize risk of exposure of the fetus to the therapeutic monoclonal antibody both in utero and after delivery.

Journal ArticleDOI
TL;DR: The association between mycobacteria and CD, the concerns with the practice of antituberculosis medication trials in areas where tuberculosis (TB) is endemic, as well as extrapulmonary TB induced by the use of antitumor necrosis factor-α agents are delineated.

Journal ArticleDOI
TL;DR: Focal-type and diffuse-type AIP differ as regards clinical symptoms and signs, and the use of non-steroid immunosuppressants may be a therapeutic option in relapsing AIP.

Journal ArticleDOI
TL;DR: There are striking clinical and pathological resemblances between the bowel diseases observed in CGD and Crohn's disease, supporting the possibility of mechanistic similarities in their pathogenesis.

Journal ArticleDOI
TL;DR: In patients with cirrhosis, the existence of hyponatremia is a major risk factor of the development of overt hepatic encephalopathy, particularly myo-inositol (MI) and patients with low brain MI levels had a higher probability of development of Overt HE compared with that of patients with high brain MI Levels.

Journal ArticleDOI
TL;DR: Prevalence and incidence rates in Hispanics and Asians with IBD have recently increased and there are many similarities and differences in disease location and behavior among racial/ethnic groups.