Showing papers in "The American Journal of Medicine in 1973"

TL;DR: The incidence of aspergillosis is increasing and should be considered in the setting of progressive pulmonary infiltrates in leukemic and other heavily immunosuppressed patients who respond poorly to antibacterial therapy.

TL;DR: This bipolar analysis assumes that chronic hypertension is maintained by (1) arterial overfilling (volume hypertension), (2) arteriolar constriction without increased volume (vasoconstrictor hypertension) or (3) an inappropriate interaction of the two.

TL;DR: In this paper, a large-scale study of 200 patients with anginal pain and myocardial lactate production (myocardial ischemia) was performed, with an average age of 47 years.

TL;DR: Of 371 patients with hypertension who were observed for two months to 20 years and who were initially treated with from 100 to 1,600 mg of hydralazine daily, late toxic manifestations to the drug developed in 44, including serious in 14.

TL;DR: Analysis of the data supports the view that abnormal renin secretion is intimately involved in the pathogenesis of curable renovascular hypertension in man.

TL;DR: It is suggested that the theory and technics of decision analysis provide new and useful strategies appropriate for dealing with complex clinical situations and, when applied quantitatively, the formalism affords greater precision than is otherwise readily attainable.

TL;DR: The results obtained in hospitalized patients indicate that the manifestations of rheumatoid arthritis form a spectrum in which extra-articular features should be considered as classic criteria of rhematoid arthritis, and these extra-Articular features appear to have an important bearing on prognosis.

TL;DR: Hemodynamic studies are reported in 50 patients with bacteremic shock, and failure of cardiac output to improve following plasma volume expansion suggests impaired cardiac function in some patients.

TL;DR: The literature dealing with preleukemia has been reviewed and the data compared with the clinical findings in 34 patients in whom an ill defined hematologic syndrome antedated the development of acute leukemia indicate that the clinical and laboratory manifestations of the early phases of leukemia are less heterogeneous than has been generally assumed.

TL;DR: The results indicate that glucagon excess is present in most patients hospitalized with diabetic ketoacidosis and are compatible with the view that glucagons, an insulin-opposing hormone, may increase the severity of the disease and its insulin requirements.

TL;DR: There is evidence for two intrarenal receptors in the control of renin release; evidence favors a beta receptor for mediation of the renal nerve mechanism and a number of humoral agents, including epinephrine and norepinephrine, sodium and potassium ions, antidiuretic hormone and angiotensin II, influence reninRelease.

TL;DR: In this article, 10,000 men aged 40 years and over were examined; those without myocardial infarction or angina pectoris were followed for the next 5 years (1963-1968) to see what factors (variables) found in 1963 were associated with the development of angina Pectoris by 1968.

TL;DR: Findings suggest a common pathogenetic mechanism, and disordered cellular immune reactions directed primarily against the liver could affect other organs as a result of cross antigenicity.

TL;DR: It appears that the greatest danger to the patient with a brain abscess is not infection, but the mass effect of the abscess, and a combination of wide spectrum antibiotics and surgical excision yields superior results over other methods of treatment.

TL;DR: In this article, it was suggested that the rise in arterial pressure in this group results from a failure of renin to suppress normally with sodium retention, which may perpetuate the hypertension.

TL;DR: Study of immunoglobulin on the surface of lymphocytes has helped to define the cellular origin and monoclonal nature of CLL, the source of circulating M components in this disease, and the relationship of Coll to other lymphoproliferative disorders.

TL;DR: The clinical course in 36 cases of Pseudomonas pneumonia collected over a 15-year period (1956 to 1970) at the Clinical Center of the National Institutes of Health were reviewed to identify factors which increased the risk of infection and affected prognosis.

TL;DR: It is concluded that computer-aided management with the aid of decision analysis is a promising area for further investigation.

TL;DR: The principal features of normal and malignant histiocyte differentiation are reviewed and correlated with clinical syndromes and a simplified classification of the malignant Histiocytoses based on cellular differentiation is presented.

TL;DR: Attention to the auscultatory features of acute tricuspid regurgitation was the predominant factor leading to early diagnosis in heroin addicts admitted to Washington, D.C. General Hospital.

TL;DR: The data appear to support the hypothesis that Werner's syndrome may represent a hereditary systemic mesenchymal disease.

TL;DR: One of the major challenges to the clinician is to identify those hypertensive subjects in whom the underlying pathologic process is most acutely progressive.

TL;DR: The protracted clinical course of chronic aortic regurgitation is confirmed: the asymptomatic state is present for decades in patients with severe aorti regurgitated even though serious hemodynamic deterioration can be documented.

TL;DR: Pulmonary and disseminated infection developed in two patients with acute leukemia who were under intensive chemotherapy, and they died following rupture of a brain abscess into the ventricular system.

TL;DR: Subjects with combined hyperlipoproteinemia manifested characteristics that are usually prevalent in type IV kindreds; that is, impaired glucose tolerance, obesity and hyperuricemia, whereas clinical characteristics of the familial type II disorder, notably xanthomas, were absent.

TL;DR: The hepatitis B antigen (HBAg) was detected in 17 of 31 infants whose mothers had acute hepatitis B while pregnant or in the first 2 postpartum months and an occasional neonate in whom acute icteric hepatitis B develops may experience rapid healing with prompt loss of antigenemia followed by the development of significant HBAb titers.

TL;DR: Free cortisol excretion provided the most definitive index of adrenocortical hyperfunction and was not adequately suppressible with dexamethasone.

TL;DR: In good risk patients, the pair prednisone-melphalan was significantly better than melphalan alone, being associated with more than twice the rate of good responses and with a longer survival and a shorter survival in poor risk patients.

TL;DR: The over-all frequency of NBTE was double that observed in other reported autopsy series not limited to patients with cancer, and complications ofNBTE should be anticipated particularly in patients with those cancers most often associated with vegetative endocarditis.

TL;DR: There was no change in the incidence of Staphylococcus aureus endocarditis between 1940 and 1971; the corresponding per cent mortality in the last decade of the study was lower, namely, 14 and 71 per cent.