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Showing papers in "The Annals of Thoracic Surgery in 1999"


Journal ArticleDOI
TL;DR: Use of perioperative continuous intravenous insulin infusion in diabetic patients undergoing open heart surgical procedures significantly reduces major infectious morbidity and its associated socioeconomic costs.

1,202 citations


Journal ArticleDOI
TL;DR: It is suggested that off pump coronary revascularization offers a superior renal protection when compared with conventional coronary Revascularization with cardiopulmonary bypass and cardioplegic arrest in first time coronary bypass patients.

415 citations


Journal ArticleDOI
TL;DR: This review article summarizes the recent literature on the molecular and cellular mechanisms involved in the phenomenon of pulmonary dysfunction after cardiopulmonary bypass and summarizes reports on the prevalence and mortality of acute respiratory distress syndrome after cardiac surgery.

399 citations


Journal ArticleDOI
TL;DR: Diabetics have a worse hospital and longterm outcome after coronary artery bypass grafting, and the increased risk in such patients can only partially be explained by other demographic characteristics.

398 citations


Journal ArticleDOI
TL;DR: The safe intervals calculated from measured cerebral oxygen consumption suggest that shorter intervals and lower temperatures than those currently used may be necessary to assure adequate cerebral protection during hypothermic circulatory arrest.

363 citations


Journal ArticleDOI
TL;DR: The rationale for conducting REMATCH is discussed, the obstacles to designing this and other randomized surgical trials, the lessons learned in conducting the multicenter pilot study, and the features of the REMATCH study design are considered.

353 citations


Journal ArticleDOI
TL;DR: Modulation of the inflammatory response constitutes a potential pharmacological target to protect the heart from reperfusion injury and should aid in development of pharmacological interventions to selectively or collectively attenuate the sequence of events that mediate extension of tissue injury beyond that caused by the ischemic insult.

350 citations


Journal ArticleDOI
TL;DR: Direct myocardial gene transfer with phVEGF165 via a mini-thoracotomy can be performed safely and may result in significant symptomatic improvement in patients with "inoperable" coronary artery disease.

337 citations


Journal ArticleDOI
TL;DR: Autologous aortic grafts with biological characteristics resembling the native aorta can be created using TE approach and may allow the development of "live" vascular grafts.

321 citations


Journal ArticleDOI
TL;DR: Compared with conventional coronary artery bypass grafting, coronary revascularization without cardiopulmonary bypass is associated with reduced cytokine responses and less myocardial injury.

314 citations


Journal ArticleDOI
TL;DR: Resection and repair of SVAF entails an acceptably low operative risk and yields long-term freedom from symptoms, which causes worse symptoms and necessitates more extensive repair.

Journal ArticleDOI
TL;DR: Excellent early and late surgical results can be obtained in patients with benign valve tumors, and the prognosis for patients with a malignant valve tumor is poor.

Journal ArticleDOI
TL;DR: This large, multiinstitutional database is capable of determining modern operative risk and should provide standards for acceptable care and illustrates the importance of risk stratification for early death both for the patient and the surgeon.

Journal ArticleDOI
TL;DR: This study reviews the ongoing efforts to understand the factors influencing aortic growth rates and the complications of rupture and dissection in order to define scientifically sound criteria for surgical intervention and recommends 5.5 cm as an acceptable size for elective resection of ascending aorta.

Journal ArticleDOI
TL;DR: In select patients with severe congestive heart failure, mechanical unloading with an LVAS can result in recovery of myocardial function and these patients can return to a normal physical status, thereby avoiding heart transplantation.

Journal ArticleDOI
TL;DR: The clinical results obtained throughout this experience have demonstrated that selective antegrade cerebral perfusion with cold blood provides excellent protection during surgery of the transverse aortic arch, and it is the technique of choice, especially in frail patients or those requiring a long and difficult procedure.

Journal ArticleDOI
TL;DR: In this article, the authors compared minimally invasive video-assisted thoracic surgery (VATS) with thoracotomy and found that the latter may offer faster recovery for severely activity-impaired patients.

Journal ArticleDOI
TL;DR: Octogenarians can undergo cardiac surgical procedures at a reasonable risk and show remarkable improvement in their symptoms and benefit from improved functional status and quality of life.

Journal ArticleDOI
TL;DR: PET was more accurate than CT in detecting distant metastases, but was only 69% sensitive compared with minimally invasive staging.

Journal ArticleDOI
TL;DR: It is concluded that inflammatory pseudotumors of the lung are rare, they often occur in children, can grow to a large size, and are often locally invasive, requiring significant pulmonary resection.

Journal ArticleDOI
TL;DR: Stages I and II have better survival rates than generally assumed for MPM, and Locally advanced T and N status, and nonepithelial histology, identify poor prognosis patients who should be considered for novel treatment regimens.

Journal ArticleDOI
TL;DR: The need for perioperative RVAD support was low, only 11%, and preoperative low PAP and low RV SWI were significant risk factors for RVAD use.

Journal ArticleDOI
TL;DR: After minimally invasive procedures with lateral minithoracotomy, earlier mobilization is possible because of a better stability of the bony thorax, resulting in lower pain levels, and overall pain levels are relatively low.

Journal ArticleDOI
TL;DR: Satisfactory results were achieved using this "first-generation" homemade stent graft device, but continued aortic enlargement, with the late development of endoleaks, is a significant concern.

Journal ArticleDOI
TL;DR: The incidence and severity of clinically apparent temporary neurological dysfunction correlates significantly with poor performance on neuropsychological tests 1 week postoperatively, and such poor performance predicts continued deficits in memory and motor function at 6 weeks.

Journal ArticleDOI
TL;DR: The button modification of the Bentall procedure has been used in 250 patients at Mount Sinai Medical Center, with a hospital mortality of 4% and excellent long-term survival as mentioned in this paper.

Journal ArticleDOI
TL;DR: This study suggests that avoidance of aortic clamping, resection of the primary tear in the ascending aorta or transverse arch, and antegrade perfusion after completion of the distal anastomosis improve the early and late outcomes of surgery for acute type A aorti dissection.

Journal ArticleDOI
TL;DR: Lasting recovery can be reached by ventricular unloading in a subset of patients with intractable end-stage dilated cardiomyopathy, and an individual optimum of recovery that cannot be further improved by prolonged unloading is reached.

Journal ArticleDOI
TL;DR: When appropriately applied in selectedOctogenarians, cardiac surgery can be performed with acceptable mortality and excellent 5-year survival, but after 5 years there is a more rapid decline in octogenarians than in younger age groups.

Journal ArticleDOI
TL;DR: Off-pump revascularization offers a safe, cost-effective alternative to conventional coronary revascularized with cardiopulmonary bypass and cardioplegic arrest.