The Journal of Pathology and Bacteriology 

About: The Journal of Pathology and Bacteriology is an academic journal. The journal publishes majorly in the area(s): Haemolysis & Carcinoma. It has an ISSN identifier of 0368-3494. Over the lifetime, 5300 publications have been published receiving 121983 citations.

The classification of cancer of the rectum

Abstract: Cancers of the rectum can be divided into A B and C cases according to the extent of spread. A cases are those in which the growth is limited to the wall of the rectum: B cases those in which there is extrarectal spread but no lymphatic metastases; C cases those in which metastases are present in the regional lymph nodes. A striking difference is found in the operative mortality rate and in the survival period after operation in these three groups. There is reason to believe that in A cases the disease is completely eradicated by rectal excision and the excellent results of operative treatment confirms the opinion previously expressed that lymphatic metastases are not found until a rectal carcinoma has spread by direct continuity to the extrarectal tissues. A good prognosis is justified also in B cases, though slightly less favourable than in A. The results of surgical treatment in C cases are very disappointing. The scope and limitations of histological grading by Broders' method are discussed and the conclusions reached that grading of a tumour is also of value for prognosis, though not when applied to fragments removed for diagnosis.