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Showing papers in "The Journal of Pediatrics in 1979"


Journal ArticleDOI
TL;DR: A simplified scoring system for clinically determining fetal maturation of newly born infants has been developed and provides accurate assessment of gestational age in either well or sick babies.

922 citations


Journal ArticleDOI
TL;DR: Reference ranges for absolute total neutrophil/mm3, absolute immature neutrophils/ mm3, and the fraction of immature to total neutophils (I:T proportion) during the first 28 days of life are developed from 585 peripheral blood counts obtained from 304 normal neonates and 320 counts from 130 neonates with perinatal complications.

732 citations


Journal ArticleDOI
TL;DR: Cerebral blood flow was measured, using the 133Xe clearance technique, a few hours after birth in 19 infants with varying degrees of respiratory distress syndrome, showing a linear relationship that was identical in infants with asphyxia at birth and infants with RDS only.

631 citations


Journal ArticleDOI
TL;DR: The finding of both discordant and concordant MZ twins with Goldenhar, de Lange, and Rubinstein-Taybi syndromes suggests that these "syndromes" might be early malformation complexes.

490 citations


Journal ArticleDOI
TL;DR: The use of mechanical ventilation in the management of the newborn with respiratory failure has improved the survival of these patients, but it has also increased the incidence of complications associated with this mode of treatment.

468 citations


Journal ArticleDOI
TL;DR: Most of the patients surviving the first month of life developed purulent rhinitis, maculopapular rashes, failure to thrive, and developmental delay, while the 24 autopsied cases constitute 0.7% of the 3,469 sequential postmortem studies done in the period 1950--1975 at The Children's Orthopedic Hospital and Medical Center.

385 citations


Journal ArticleDOI
TL;DR: A regularly recurring pattern of associated features involving mental retardation, postnatal growth deficiency, hypogenitalism (males), small ears, cardiac defects, micrognathia,Postnatal microcephaly, and ocular coloboma was identified.

383 citations


Journal ArticleDOI
TL;DR: This new syndrome, with associated bone marrow and exocrine pancreatic dysfunctions, differs in several respects from the syndrome of pancreatic liposis and neutropenia described by Shwachman et all and Bodian et al, and from other conditions with vacuolization of the marrow or sideroblastosis.

380 citations


Journal ArticleDOI
TL;DR: Pilot programs for screening of newborn infants for congenital hypothyroidism began in North America in 1972 and preliminary evidence from Quebec suggests that infants treated in the program have normal developmental testing scores at 18 months of age.

352 citations


Journal ArticleDOI
TL;DR: The percentile curves were derived from several populations of non-indigent white children who lived near sea level and should be particularly applicable to the diagnosis and screening of iron deficiency and thalassemia minor.

293 citations


Journal ArticleDOI
TL;DR: Comparison of 35 cases in which the timing of amniotic rupture could be estimated suggests that early amniotics rupture results in multiply affected infants who are frequently aborted or stillborn, whereas later rupture results primarily in limb involvement.

Journal ArticleDOI
TL;DR: The most common cause of WARI in children under 5 years of age was RSV whereas Mycoplasma pneumoniae was the most frequent isolate from school age children with wheezing illness, and patient age influenced the pattern of recovery of these agents.


Journal ArticleDOI
TL;DR: Until other methods are devised, this test should be considered in any patient thought to have significant GER and HC1 should be removed from those infants found to have gross GER or from those whose symptoms have been apnea or recurrent pneumonia.

Journal ArticleDOI
TL;DR: Prolonged monitoring of esophageal pH more than two hours after feeding in 14 infants less than 6 weeks of age without a history of recent vomiting indicated that reflux was not greater than in normal older children.


Journal ArticleDOI
TL;DR: Monitoring the pulsatile flow changes in the anterior cerebral arteries using Doppler ultrasound determined the cerebrovascular hemodynamic alterations in asphyxia and intracerebral-intraventricular hemorrhage, which indicate vasodilation and decreased resistance to blood flow in infants with respiratory distress and in those with IC-IVH.

Journal ArticleDOI
TL;DR: In 37 children with Campylobacter enteritis seen over a 6-month period, ages ranged from 2 weeks to 15 years, the sex ratio was three:two, and infection occurred in all social classes and was not associated with parental occupation, travel, or animal contact.

Journal ArticleDOI
TL;DR: A hypothesis for the embryogenic pathogenesis of the MURCS association is proposed which attributes the malformations to an alteration of the blastemas of the lower cervical-upper thoracic somites, arm buds, and pronephric ducts, all of which have an intimate spatial relationship at the end of the fourth week of fetal life.


Journal ArticleDOI
TL;DR: The data suggest that although most toddlers do not have major side effects from phenobarbital therapy when treated for a year, serum levels and length of time on phenobarBital should be kept at a minimum to reduce negative cognitive and behavioral effects.

Journal ArticleDOI
TL;DR: Recurrent vomiting is a common and serious problem in severely retarded children, the organic cause of which can be demonstrated by the application of appropriate investigative techniques.

Journal ArticleDOI
TL;DR: Honey is now an identified and avoidable source of C. botulinum spores, and it therefore should not be fed to infants, and is significantly associated with type B infant botulism.

Journal ArticleDOI
TL;DR: Co-existing proteinuria and the degree of hematuria correlated well with the severity of the morphologic alterations; in most such patients, renal biopsy is probably not indicated; in some children the low-grade hematurIA may merely represent the upper end of physiologic variation.

Journal ArticleDOI
TL;DR: Analysis of ventilatory functions of 1,805 normal Mexican-American, white, and black students of six public schools in Houston, Texas finds significant differences of lung volume and flow rate exist among the three races, and between male and female subjects.

Journal ArticleDOI
TL;DR: There were significant racial and geographic differences in the age of development of secondary sexual characteristics and there was a close relationship between Tanner rankings of sexual maturity and both bone age and body mass index (weight/height).

Journal ArticleDOI
TL;DR: Evidence is presented that abdominal muscle deficiency is an etiologically nonspecific anatomic defect which is secondary to fetal abdominal distention of various causes, and this interpretation of the etiology of most cases of prune belly syndrome accounts for the male predominance, the observed variability in severity and the lack of a defined mode of inheritance.


Journal ArticleDOI
TL;DR: The medical and surgical therapy of 82 cases of atypical mycobacterial adenitis from Dallas and 298 cases from the literature was reviewed and it was concluded that total surgical excision is definitive therapy for this disease.

Journal ArticleDOI
TL;DR: Data is presented suggesting that the presence of a PDA complicating the course of RDS increases the risk of BPD, and particularly striking in infants weighing less than 1,250 gm, in whom the incidence of PDA in those with BPD was 84%.