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Showing papers in "The Journal of Pediatrics in 1999"


Journal ArticleDOI
TL;DR: Zinc supplementation in children in developing countries is associated with substantial reductions in the rates of diarrhea and pneumonia, the 2 leading causes of death in these settings.

689 citations


Journal ArticleDOI
TL;DR: Lactobacillus GG reduces the incidence of antibiotic-associated diarrhea in children treated with oral antibiotics for common childhood infections and increases stool consistency during antibiotic therapy by the tenth day compared with the placebo group.

542 citations


Journal ArticleDOI
TL;DR: The observed increase in pancreatico-biliary secretion after secretin infusion suggests an upregulation of secretin receptors in the pancreas and liver and may contribute to the behavioral problems of the non-verbal autistic patients.

481 citations


Journal ArticleDOI
TL;DR: In utero exposure to "background" PCB concentrations is associated with poorer cognitive functioning in preschool children, and children of mothers at the upper end of exposure are especially at risk.

438 citations


Journal ArticleDOI
TL;DR: PFAPA is a not uncommon cause of periodic fever in children and in some children the syndrome resolves, whereas symptoms in others persist, and long-term sequelae do not develop.

430 citations


Journal ArticleDOI
TL;DR: In this paper, the extent to which physical activity and inactivity patterns vary by ethnicity among subpopulations of US adolescents was determined by the National Longitudinal Study of Adolescent Health of >14,000 US adolescents.

410 citations


Journal ArticleDOI
TL;DR: It is demonstrated that an individually tailored, multifaceted intervention carried out by Masters-level social workers trained in asthma management can reduce asthma symptoms among children in the inner city.

345 citations


Journal ArticleDOI
TL;DR: It is concluded that MRI abnormalities are commonly seen in the brain of preterm infants on whom images are obtained within 48 hours of birth and that further abnormalities develop between birth and term.

340 citations



Journal ArticleDOI
TL;DR: L-GG supplementation may be useful as a prophylactic measure to control diarrhea in undernourished children at increased risk, especially nonbreastfed children in the toddler age group.

301 citations


Journal ArticleDOI
TL;DR: The IQ and academic profiles are reminiscent of a "nonverbal learning disability," although achievement was not discrepant from IQ, and educational programming for these children must address both verbal and nonverbal deficits.

Journal ArticleDOI
TL;DR: Serum phenylalanine concentrations decreased in 4 patients with hyperphenylalaninemia after loading with tetrahydrobiopterin, suggesting a novel subtype of phenylAlanine hydroxylase deficiency that may respond to treatment with cofactor supplementation.

Journal ArticleDOI
TL;DR: Clinical neonatal seizures occur 6 times more often in preterm infants than in term infants, and Hypoxic-ischemic encephalopathy continues to be a major marker of the likelihood of seizures.

Journal ArticleDOI
TL;DR: Because most infants with congenital CMV infection are without symptoms at birth, these children are unlikely to be recognized as being at risk for SNHL and will not receive further hearing evaluations to detect late-onset hearing loss.

Journal ArticleDOI
TL;DR: Early IVIg replacement therapy achieving residual IgG levels >500 mg/dL is effective in preventing severe acute bacterial infections and pulmonary insufficiency and more intensive therapy may be required to fully prevent the onset of bronchiectasis, chronic sinusitis, and nonbacterial infections, particularly enteroviral infections, in all cases.

Journal ArticleDOI
TL;DR: Attacks were aborted by a single dose of oral prednisone at the beginning of the attack in all 15 patients in whom this medication was prescribed, and the syndrome has completely resolved in 9 patients.

Journal ArticleDOI
TL;DR: A simple, quantifiable, neurologic examination for infants between 2 and 24 months of age, designed according to the frequency distribution of the neurologic findings, which enhances the value of this examination, both in clinical practice and in research settings.

Journal ArticleDOI
TL;DR: In this article, the authors investigated the effects of neonatal hypoglycemia on physical growth and neurocognitive function, and proposed a systematic detection method to diagnose and diagnose neonatal hyperglycemia.

Journal ArticleDOI
TL;DR: The respiratory improvement after T&A in children with OSAS is associated with a significant increase in serum IGF-I levels and weight, and it is concluded that the insulin-like growth factor-I axis is affected in childrenwith OSAS.

Journal ArticleDOI
Sunita Vohra1, Gilda Frent1, Valerie Campbell1, Michele Abbott1, Robin Whyte1 
TL;DR: Occlusive wrapping of very low birth weight infants at delivery reduces postnatal temperature fall, which may result in a decreased mortality rate and increase the likelihood of survival in the delivery room.

Journal ArticleDOI
TL;DR: Soy formula may provide a safe and growth-promoting alternative for the majority of children with IgE-associated CMA shown to be soy tolerant at the time of introduction of soy formula.

Journal ArticleDOI
TL;DR: Children with LKSV and ASD have a greater frequency of serum antibodies to brain endothelial cells and to nuclei than children with NNIs or healthy children, which raises the possibility that autoimmunity plays a role in the pathogenesis of language and social developmental abnormalities in a subset of children with these disorders.

Journal ArticleDOI
TL;DR: Compared with indomethacin, ibuprofen did not significantly reduce mesenteric and renal blood flow velocity, and blood flow increased 120 minutes after treatment.

Journal ArticleDOI
TL;DR: Left-sided lesions, such as aortic coarctation and anomalies of the mitral valve, are not rare in patients with NS and CHD, and this information should be taken into consideration during the cardiologic evaluation of children with NS.

Journal ArticleDOI
TL;DR: Clinical features among patients with Shwachman syndrome varied between patients and with age, and similarities in phenotype between isolated cases and affected sibling sets support the hypothesis that Shwacman syndrome is a single disease entity.

Journal ArticleDOI
TL;DR: Intermittent stimulation of the left vagal nerve appears to be a safe, adjunctive therapy for the treatment of children with epilepsy intractable to available antiepileptic drugs and the reduction in seizure frequency in children was similar to that reported in adults.

Journal ArticleDOI
TL;DR: In this article, the authors evaluated sixteen children with insulin-dependent diabetes mellitus at diagnosis and after 1, 3, and 7 years, and found significant declines in verbal but not visuospatial abilities, particularly if they had any seizures from hypoglycemia.

Journal ArticleDOI
TL;DR: GH treatment of children with Prader-Willi syndrome accelerated growth, decreased percent body fat, and increased fat oxidation but did not significantly increase total REE, suggesting that GH treatment may have value in reducing some physical disabilities experienced by children with PWS.

Journal ArticleDOI
TL;DR: Patients with a diverse group of malignancies, other than leukemia, may present to the pediatric rheumatologist and rheumatic diagnoses should be reevaluated in the presence of any atypical or discordant clinical features.

Journal ArticleDOI
TL;DR: Reduced serum levels of fat-soluble antioxidants are present in obese children, including β-carotene, which is linked to greater risks of cardiovascular disease in epidemiologic studies.