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JournalISSN: 1751-1437

The journal of the Intensive Care Society 

SAGE Publishing
About: The journal of the Intensive Care Society is an academic journal published by SAGE Publishing. The journal publishes majorly in the area(s): Intensive care & Intensive care unit. It has an ISSN identifier of 1751-1437. Over the lifetime, 1257 publications have been published receiving 10027 citations. The journal is also known as: JICS.


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Journal ArticleDOI
TL;DR: This benchmark paper stresses the need for family-centred, long-term rehabilitation after a prolonged critical illness and the increased costs of healthcare services associated with critical illness following survival from acute respiratory distress syndrome.
Abstract: This prospective, longitudinal study is an extension of the seminal work by Herridge,1 which sheds light into the physical and psychological impairment, and the increased costs of healthcare services associated with critical illness following survival from acute respiratory distress syndrome (ARDS). This benchmark paper stresses the need for family-centred, long-term rehabilitation after a prolonged critical illness.Level of evidence: 2C (Outcome/follow-up study)

969 citations

Journal ArticleDOI
TL;DR: Intensive glucose control with a target blood glucose 4.5–6.0 mmol/L increases the risk of death at 90 days and severe hypoglycaemia and the number needed to harm (NNH) is 38.
Abstract: Intensive glucose control with a target blood glucose 4.5–6.0 mmol/L increases the risk of death at 90 days (number needed to harm (NNH)=38) and severe hypoglycaemia (NNH=16).Level of evidence: 1+ (RCT with a low risk of bias)

933 citations

Journal ArticleDOI
TL;DR: Mechanical ventilation without sedation reduces duration of ventilation and the likelihood of adverse events is higher in patients treated with mechanical ventilation than without.
Abstract: Mechanical ventilation without sedation reduces duration of ventilation.Level of evidence: 1− (RCT with a high risk of bias)

341 citations

Journal ArticleDOI
TL;DR: Enteral feeding to deliver a moderate amount of nonprotein calories to critically ill adults was not associated with lower mortality than that associated with planned delivery of a full amount ofnonprotein calories.
Abstract: BACKGROUND The appropriate caloric goal for critically ill adults is unclear. We evaluated the effect of restriction of nonprotein calories (permissive underfeeding), as compared with standard enteral feeding, on 90-day mortality among critically ill adults, with maintenance of the full recommended amount of protein in both groups. METHODS At seven centers, we randomly assigned 894 critically ill adults with a medical, surgical, or trauma admission category to permissive underfeeding (40 to 60% of calculated caloric requirements) or standard enteral feeding (70 to 100%) for up to 14 days while maintaining a similar protein intake in the two groups. The primary outcome was 90-day mortality. RESULTS Baseline characteristics were similar in the two groups; 96.8% of the patients were receiving mechanical ventilation. During the intervention period, the permissiveunderfeeding group received fewer mean (±SD) calories than did the standardfeeding group (835±297 kcal per day vs. 1299±467 kcal per day, P<0.001; 46±14% vs. 71±22% of caloric requirements, P<0.001). Protein intake was similar in the two groups (57±24 g per day and 59±25 g per day, respectively; P = 0.29). The 90-day mortality was similar: 121 of 445 patients (27.2%) in the permissive-underfeeding group and 127 of 440 patients (28.9%) in the standard-feeding group died (relative risk with permissive underfeeding, 0.94; 95% confidence interval [CI], 0.76 to 1.16; P = 0.58). No serious adverse events were reported; there were no significant between-group differences with respect to feeding intolerance, diarrhea, infections acquired in the intensive care unit (ICU), or ICU or hospital length of stay. CONCLUSIONS Enteral feeding to deliver a moderate amount of nonprotein calories to critically ill adults was not associated with lower mortality than that associated with planned delivery of a full amount of nonprotein calories. (Funded by the King Abdullah International Medical Research Center; PermiT Current Controlled Trials number, ISRCTN68144998.)

265 citations

Performance
Metrics
No. of papers from the Journal in previous years
YearPapers
202325
202245
2021100
202097
201971
201863