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Showing papers in "The Journal of Urology in 1990"


Journal ArticleDOI
TL;DR: The prostate cancer detection rate from screening by digital rectal examination and tactilely guided prostate biopsy is approximately 1.7%, and the possible benefit to be derived from an improved detection rate is undetermined.

759 citations


Journal ArticleDOI
TL;DR: Serum prostate specific antigen levels do not reflect tumor burden and pathological stage accurately in individual patients for 2 reasons: 1) the unpredictable contribution from the benign prostatic hyperplasia component of the gland and 2) the decreasing production of prostatespecific antigen by higher grade lesions as tumor volume increases.

590 citations


Journal ArticleDOI
P.G. Ransley1, H.K. Dhillon1, I. Gordon1, P.G. Duffy1, M.J. Dillon1, T.M. Barratt1 
TL;DR: It is proposed that there is no indication for immediate pyeloplasty in infants with prenatally diagnosed hydronephrosis who demonstrate good function postnatally who demonstrate improvement in function postoperatively.

422 citations


Journal ArticleDOI
TL;DR: In this paper, the natural history of Peyronie's disease was evaluated in 97 men by means of a questionnaire and the duration of the disease ranged from 3 months to 8 years.

414 citations



Journal ArticleDOI
TL;DR: It is concluded that with proper application of nerve-sparing radical retropubic prostatectomy, potency can be preserved in the majority of patients without compromising the adequacy of tumor excision.

379 citations


Journal ArticleDOI
TL;DR: This work reviews the various reports on malignancies in bladder augmentations and urinary conduits and compares these data to those known about malignancy arising in the colon after ureterosigmoidostomy.

369 citations


Journal ArticleDOI
TL;DR: It would appear that the surface polysaccharide may play an important role as a bladder permeability barrier in modulating both charged and uncharged small molecule movement in that its ability to impair such movement can be inhibited by protamine and this protamine effect can be reversed by a treatment with an exogenous sulfated poly Saccharide.

344 citations


Journal ArticleDOI
TL;DR: Even longer followup is needed to assess more clearly the definitive role of simple enucleation in the treatment of renal cell carcinoma and the clinical relevance of possible positive margins in a patient population that usually is older.

290 citations


Journal ArticleDOI
TL;DR: Ejaculation is reliably preserved when this nerve-sparing technique is applied accurately in retroperitoneal lymphadenectomy, and it can even be applied to selected patients with low volume positive nodes, yet maintaining relapse and survival figures that are acceptable.

281 citations


Journal ArticleDOI
TL;DR: Positive margins were analyzed in 189 clinical stage B radical retropubic prostatectomies and found that prostate apex, rectal and lateral surfaces, bladder neck and superior pedicles accounted for 48, 24, 16 and 10% of all positive margins, respectively.

Journal ArticleDOI
TL;DR: Patients with renal cell carcinoma who underwent radical nephrectomy and extensive lymphadenectomy are studied to assess prognosis, finding patient survival in the presence of a vena caval tumor thrombus is similar to that of patients with distant metastases.

Journal ArticleDOI
TL;DR: Clinical observations and the mathematical relationship between prostate cancer prevalence and host age (time) support the fact that, in addition to growth, histological prostate cancer requires further malignant events to produce clinical disease.

Journal ArticleDOI
TL;DR: It is suggested that features of mucosal ulceration and hemorrhage are characteristic, specific and prevalent enough to allow for morphological differentiation of the 2 clinical subtypes of interstitial cystitis.

Journal ArticleDOI
TL;DR: Analysis of the 441 stage T1-2N0M0 cancer patients demonstrated that failure and survival were a function of the disease being organ-confining, specimen-confined or margin-positive, with 10-year failure rates of 12, 30 and 60%, respectively.

Journal ArticleDOI
TL;DR: Of 156 patients undergoing radical prostatectomy for localized prostatic carcinoma 18 had anastomotic stricture for an over-all incidence of 11.5%, and more than half of the patients did not respond to simple dilation alone and required periodic dilation to maintain an adequate urine flow.

Journal ArticleDOI
TL;DR: These findings provide valuable support to basic concepts of the pathophysiology of stress incontinence but also help to establish normal findings of female paraurethral and bladder neck anatomy as seen by magnetic resonance imaging.

Journal ArticleDOI
TL;DR: A technique based on the Heineke-Mikulicz principle was used to straighten penile curvature instead of Nesbit corporoplasty because of the distance between the longitudinal incision and the neurovascular bundle or corpus spongiosum these structures become less susceptible to injuries during an operation and need not be mobilized.

Journal ArticleDOI
TL;DR: It is concluded that prostate specific antigen but not digital rectal examination is an excellent early indicator of possible local recurrence after radical prostatectomy.

Journal ArticleDOI
A. Böhle1, J. Gerdes1, A.J. Ulmer1, A.G. Hofstetter1, H.-D. Flad1 
TL;DR: The results showed a marked infiltration after bacillus Calmette-Guerin therapy predominantly of the suburothelial tissue with mononuclear cells, which expressed activation markers and accumulated to follicle-like granulomatous structures.

Journal ArticleDOI
TL;DR: Clinical and histological findings indicate that interstitial cystitis is a complex disease whose diagnosis presently still must be made from a symptom complex rather than from objective histological criteria, including mastocytosis or the presence of any specific immunoreactive cell.

Journal ArticleDOI
TL;DR: In conclusion, inguinal orchiectomy is recommended as the procedure of choice for the management of chronic testicular pain when conservative measures are unsuccessful.

Journal ArticleDOI
TL;DR: Cases of mild to moderate hemorrhagic cystitis arising in the otherwise healthy patients should lead one to pursue the possibility of environmental toxins, accidental poisoning, recreational drug use or viruses.

Journal ArticleDOI
TL;DR: The sensitivity of preoperative computerized tomography is good for the detection of enlarged lymph nodes in patients with renal cell cancer, however, significant lymph node enlargement frequently may be caused by inflammatory changes, especially in the presence of tumor necrosis.

Journal ArticleDOI
TL;DR: The degree of improvement in urinary flow rates and symptom scores achieved after transurethral prostatectomy exceeds all other therapeutic options that presently are available for the treatment of benign prostatic hyperplasia.

Journal ArticleDOI
TL;DR: The results reflect the strong inflammatory response in the bladder wall to bacillus Calmette-Guerin, in which the urinary secretion of the detected cytokines may be associated with the local tumor control.

Journal ArticleDOI
TL;DR: Although the upper urinary tract was well preserved in the majority of the patients regular screening for silent hydronephrosis and/or asymptomatic reflux proved to be necessary, with a urethral pathological condition being the most frequent complication in male patients during followup.

Journal ArticleDOI
TL;DR: The relationship of seminal vesicle invasion to lymph node metastasis was statistically significant but cancer volume and histological grade were much stronger predictors of lymph nodes metastasis.

Journal ArticleDOI
TL;DR: In this series a successful outcome was achieved in 14 of 15 patients (93%) and all 13 women who had symptoms of bladder instability experienced resolution of these symptoms.

Journal ArticleDOI
TL;DR: Results suggest that at the dose, periodicity and duration used in the study bacillus Calmette-Guerin is significantly superior to the chemotherapeutic agents doxorubicin and thiotepa for the prophylaxis of recurrence and retardation of progression in superficial transitional cell bladder tumors.