Showing papers in "The Lancet in 1967"
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TL;DR: Positive end-expiratory pressure was most helpful in combating atelectasis and hypoxaemia and Corticosteroids appeared to have value in the treatment of patients with fat-embolism and possibly viral pneumonia.
3,706 citations
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TL;DR: The results strongly support the hypothesis that reagins belong to the immunoglobulin class IgND, provisionally called IgND.
1,146 citations
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TL;DR: The finding of late degenerative changes in a proportion of aortic homografts prompted the use of the patient's own pulmonary valve as a replacement, and as a living autograft, the transplanted pulmonary valve has the prospect of long-term or permanent survival, whilst retaining the advantages of an aortiograft.
828 citations
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TL;DR: It has been shown perhaps for the first time that the correction of cardiac arrest outside hospital is a practicable proposition and no death has occurred in transit in a fifteen-month period.
593 citations
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TL;DR: Extracorporeal perfusion of canine kidneys for periods of 24 to 72 hours were consistently successful and the functional viability was proved by reimplanting the perfused kidneys and simultaneously removing the contralateral kidneys.
429 citations
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TL;DR: Significantly raised serum levels of a new class of immunoglobulins, provisionally called IgND, were found in 63% of patients with allergic asthma compared to 5% of customers with non-allergic asthma, indicating that IgND has many characteristics in common with reagins.
409 citations
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TL;DR: Measles-virus antigen was shown to be present in the brain and found in the serum and cerebrospinal fluid of three patients with subacute sclerosing panencephalitis.
372 citations
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TL;DR: Spleen cells from normal, unimmunised mice were grown on dialysis membranes above a reservoir of medium together with sheep or horse erythrocytes and antibody-producing cells appeared in significant numbers in the cultures within 3 to 5 days.
357 citations
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TL;DR: In a group of patients with severe head injuries, sustained mainly in road-traffic accidents, a high early mortality was associated with an increased risk of premature death in late convalescence, and severity of neurological and of psychiatric sequelae correlated significantly with increasing duration of post-traumatic amnesia.
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TL;DR: It is postulate that chronic hepatic disease produces endogenous insulin resistance and hyperinsulinaemia before glucose tolerance is impaired, and that diabetes ensues when β-cell decompensation occurs and remains an enigma.
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TL;DR: In normal men, aged 25-40 years, ingestion of 3 g.
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TL;DR: Patients with severe renal failure had red eyes in association with a raised serum-inorganic-phosphate but a normal or low serum-calcium, and the importance of hyperphosphataemia is stressed.
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TL;DR: Uric-acid levels in both urine and serum rose dramatically, indicating increased uric-acid production, in controls and children with H.F.I. but not in the man with essential fructosuria, suggesting fructose-induced hyperuricaemia is brought about by the overproduction of lactic acid.
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TL;DR: The patients given tryptophan and a monoamine-oxidase inhibitor tended to show a greater improvement than those treated by tryPTophan alone, and the addition of potassium and carbohydrate may also enhance the antidepressive activity of tryptophile and a Monoamine-Oxidase inhibitors.
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TL;DR: The need for zinc in the optimal healing of wounds was demonstrated by the acceleration of healing of granulating wounds caused by excision of pilonidal-sinus tracts in young, healthy airmen who were given zinc sulphate U.S.P. by mouth during the period of repair.
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TL;DR: Though the effects of this are not underestimated, lack of effective communication between medical workers and the immigrant group in all probability had a greater bearing on the qualitative use made of services.
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TL;DR: It is suggested that antibacterial drugs other thanPenicillin should not be used to treat acute sore throats except in patients who are sensitive to penicillin, when erythromycin should be used.
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TL;DR: Equilibration with interstitial fluid in non-œdematous patients takes less than 2 hours and there is no detectable extrarenal uptake so that the " slope " method based on 2-4-hour plasma-activity measurements can be used as a simple routine procedure.
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TL;DR: In this article, the raised urinary excretion of p -hydroxyphenylacetic acid in children with cystic fibrosis has been confirmed, and it was suggested that unabsorbed tyrosine in the lumen of the large bowel is decarboxylated and then absorbed when it could be oxidised in the liver to p-hydroxymhenyl acetic acid.
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TL;DR: A double-blind cross-over sequential trial of a new antiallergic compound, disodium cromoglycate (' FPL670 ','Intal ') was carried out over a period of 6 weeks in ten patients severely disabled with allergic bronchial asthma.
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TL;DR: The hypothesis outlined here, by delineating the basic components of haemopoiesis, provides a framework for further analysis of ha Hemopoietic defects and the mechanisms of immunogenesis.
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TL;DR: The site of urinary-tract infection can be determined in most cases by a simple technique which entails only catheterisation of the bladder, and would only be necessary in a few patients in whom low bacterial counts persisted after the bladder washout.
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TL;DR: It is found that the disease is genetically determined, being transmitted in a sex-linked manner, and that a combined phagocytosis/histochemical procedure demonstrates two populations of cells in the isolated leucocytes of the carrier females.