Showing papers in "The Lancet in 1974"
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TL;DR: A clinical scale has been evolved for assessing the depth and duration of impaired consciousness and coma that facilitates consultations between general and special units in cases of recent brain damage, and is useful also in defining the duration of prolonged coma.
12,002 citations
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TL;DR: For assessing response to treatment, a pain-relief scale has advantages over a pain scale as discussed by the authors, which cannot be said to have been relieved unless pain or pain relief has been directly measured.
3,652 citations
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TL;DR: The presence of organ-specific pancreatic antibodies supports the hypothesis of an autoimmune form of diabetes mellitus put forward to explain the histological " insulitis " found in selected cases of this disease.
1,495 citations
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TL;DR: The data suggest that lipoid nephrosis is a clinical expression of a self-limited primary immune-deficiency disease that is of primary or secondary pathogenetic importance.
1,089 citations
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TL;DR: The investigation and precise diagnosis of all cases of dementia allow a more accurate prognosis and more rational management of the significant number of cases in which dementia is due to treatable conditions.
987 citations
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TL;DR: Patients with haematemesis were admitted to hospital earlier and had endoscopy more quickly than patients with melaena alone; this probably accounted for the higher endoscopic success-rate in this group.
816 citations
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TL;DR: The increase of HL-A8 in insulin-dependent diabetes, Graves' disease, and idiopathic Addison's disease is suggestive of a common pathogenesis of these endocrine autoimmune conditions.
705 citations
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TL;DR: The results suggest that it is possible to prepare a live varicella vaccine which may be safely and effectively used for high-risk children as well as normal children.
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TL;DR: Theses studies suggest that in some patients the disease common variable hypogammaglobulinaemia may be caused or perpetuated by an abnormality of regulatory T cells which act to suppress B-cell maturation and antibody production.
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TL;DR: This paper found that differences in height and weight between well-fed preschool children and those of similar ethnic and geographical background who live in the poor, urban and rural regions of developing countries approach 12% in height, and 30% in weight, respectively.
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TL;DR: It is suggested that reduction of information-processing rate is an important factor in the genesis of the post-concussion syndrome.
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TL;DR: The hypothalamic polypeptide growth-hormone release-inhibiting hormone (G.H.R.I.H.) inhibited gastrin release in all subjects studied and greatly lowered plasma-gastrin concentrations and almost totally suppressed gastric-acid production.
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TL;DR: Comparison of the effects of Graves' immunoglobulins on the binding of T.S.H. to human and guineapig thyroid membranes provided good evidence for the species specificity of some thyroid-stimulating immunoglOBulins.
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TL;DR: Two-thirds of the first-attack patients who went into remission remained symptom-free during the period of follow-up, which averaged more than 3 years, and the regimen gives a considerable chance of a prolonged remission.
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TL;DR: A new method for the quantitative determination of platelet aggregates has been developed which uses a platelet-count ratio technique and was applied to the study of normal subjects and patients with arterial insufficiency.
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TL;DR: The histological evolution, the widespread organ involvement, and the clinical pattern are very similar to those of a graft-versus-host reaction.
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TL;DR: The irradiated group had a significantly higher risk of both malignant and benign head and neck tumours, especially those in the brain, the parotid gland, and the thyroid.