Showing papers in "The Lancet in 1979"

TL;DR: 34 patients treated with cyclosporin A received 36 cadaveric organ allografts, 26 kidneys are still supporting life, 3 after more than a year; the pancreases and livers are also functioning.

TL;DR: Partial dietary substitution of arachidonic acid by eicosapentaenoic acid may reduce the incidence of thrombotic disorders, including myocardial infarction, among Eskimos.

TL;DR: Recurrence-free survival was significantly common among patients who had initially reacted to cancer by denial or who had a fighting spirit than among patientsWho had responded with stoic acceptance or feelings of helplessness and hopelessness.

TL;DR: There is a strong and specific negative association between ischaemic heart-disease deaths and alcohol consumption and this is shown to be wholly attributable to wine consumption.

TL;DR: It is suggested that the morphine reached the subarachnoid space and produced its effect by direct action on the specific opiate receptors in the substantia gelatinosa of the posterior-horn cells of the spinal cord.

TL;DR: The protein moiety of lipoproteins is a better discriminator than lipids between atherosclerotic subjects and controls and in the sixth to eighth decades.

TL;DR: A case-control study of 150 ovarian cancer patients under the age of 50 and individually matched controls was done to study the influence of fertility and oral contraceptive use on the risk of ovarian cancer, finding the risk decreased with increasing numbers of live births, with increasing number of incomplete pregnancies, and with the use of oral contraceptives.

TL;DR: It is suggested that beta-blockade prolongs survival in patients with congestive cardiomyopathy and improved myocardial function in group ISubjects received digitalis and diuretics, but group I patients received Beta-blockers as well.

TL;DR: In this article, the efficacy of oestrogens in preventing the common major limb fractures of postmenopausal women, retrospective case-control research was used for a new purpose to explore a beneficial rather than adverse effect of treatment.

TL;DR: This model, tested previously on U.S. data, has now been confirmed on data for England and Wales, and shows economic recessions and subsequent periods of rapid economic growth are associated with a deceleration in the normally declining curve of mortality against time.

TL;DR: Poor outcome could be positively associated with clinical data such as longer duration of illness, older age of onset and presentation, lower weight during illness and at presentation, presence of symptoms such as bulimia, vomiting, and anxiety when eating with others, poor childhood social adjustment, and poor parental relationships.

TL;DR: The results suggest that the effects of guar gum and pectin on glucose tolerance and paracetamol absorption could be due simply to alteration in the rate of gastric emptying.

TL;DR: Iron absorption was strikingly increased and there was a progressive iron loading with increasing age and balance studies indicated that by the time many of these patients reach the third or fourth decades their total iron loads may be of a similar magnitude to those of transfusion-dependent β-thalassaemia homozygotes.

TL;DR: Serum-immunoreactive-trypsin was measured in children with cystic fibrosis and a variety of controls and has potential as a screening test for C.F. in the newborn.

TL;DR: It is proposed that hyperammonaemia in liver cirrhosis or after portacaval shunt contributes to plasma neutral aminoacid imbalance and to increased activity of the blood-brain neutral amino-acid transport system.

TL;DR: A method for the measurement of milk intake in young breast-fed babies is described in which heavy water (2H2O) enrichment in saliva is measured on only two occasions after a single oral dose of 2H2 O.

TL;DR: A survey of 1293 patients in eighteen dialysis centres in Great Britain showed a highly significant rank correlation of the incidence of both fracturing dialysis osteodystrophy and dialysis encephalopathy with the aluminium content of water used to prepare dialysate.

TL;DR: It is suggested that Alzheimer's disease is a primary degenerative nerve-cell disorder and not the result of accelerated ageing, and there is selective loss of neocortical cholinergic neurones.

TL;DR: Analysis of the results of three randomized controlled trials of aspirin and secondary mortality in patients who had had a myocardial infarction indicates that the estimate of benefit of 17% in one of the trials is almost certainly an underestimation.

TL;DR: In 6 patients anticoagulated with warfarin, nicoumalone, or phenindione the addition of cimetidine prolonged the prothrombin-time (PT) by a mean of 12.6 s (range 5--23 s), and in 7 volunteers taking daily subtherapeutic doses ofwarfarin the added cimetamine increased the PT.

TL;DR: It is suggested that measurement of plasma-paraquat concentrations is useful in assessing the severity and predicting the outcome of poisoning.

TL;DR: In this paper, the effect of protein and energy restriction on the plasma proteins, albumin, transferrin, prealbumin, retinol-binding protein, haptoglobulins, and immunoglobulin, was studied in obese subjects.

TL;DR: It is suggested that annual revaccination with inactivated influenza-A vaccine confers no long-term advantage.