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Showing papers in "The Lancet in 1982"


Journal ArticleDOI
Gc Viberti1, R. J. Jarrett1, U. Mahmud1, R. D. Hill1, A. Argyropoulos1, Harry Keen1 
TL;DR: Elevated levels of microalbuminuria strongly predict the development of clinical diabetic nephropathy, and these levels of AER are potentially reversible, and their detection and treatment may prevent diabetic renal disease.

1,665 citations


Journal ArticleDOI
TL;DR: The clinical features of TSS not associated with menstruation and the characteristics of the S. aureus strains isolated from these patients were similar to those observed in TSS related to menstruation.

1,141 citations


Journal ArticleDOI
TL;DR: Results indicate that increased skin pigment can greatly reduce the UVR-mediated synthesis of vitamin D.

1,128 citations


Journal Article
TL;DR: The epithelioid hemangioendothelioma (EHE) as discussed by the authors is a type of cancer characterized by a histiocytoid endothelial cell, which grows in small nests or cords and only focally line well-formed vascular channels.

1,079 citations


Journal ArticleDOI
TL;DR: The hypothesis offers new approaches to the study of chronic progressive kidney disease by proposing a major pathogenetic role for lipid abnormalities, which is mediated by abnormalities of lipid metabolism.

962 citations





Journal ArticleDOI
TL;DR: Avoidance of important allergens seems not only to result in clinical remissions but in many cases also reduce bronchial hyperreactivity.

645 citations



Journal ArticleDOI
TL;DR: The wearable artificial endocrine pancreas, incorporating the needle-type glucose sensor, a computer calculating infusion rates of insulin, glucagon, or both, and infusion pumps, was tested in pancreatectomised dogs and produced perfect control of blood glucose for up to 7 days.

Journal ArticleDOI
TL;DR: A case-control study was conducted to investigate the association between serum selenium and risk of death from acute coronary heart disease (CHD) as well as risk of fetal and non-fetal myocardial infarction (MI) in an area with an exceptionally high mortality from cardiovascular diseases.


Journal ArticleDOI
TL;DR: This outbreak widens the array of neoplasms affecting immunosuppressed homosexual men and provides further evidence of an oncogenic role for EBV and CMV.

Journal ArticleDOI
TL;DR: Tests suggest that MBP in the eosinophil granule is released into respiratory tissue of patients with severe asthma and that it is associated with tissue damage.

Journal ArticleDOI


Journal ArticleDOI
TL;DR: Investigation of cases of confirmed rubella infection at different stages of pregnancy and the findings in infected children being compared with those in children who had escaped infection found no defects attributable to rubella.

Journal ArticleDOI
TL;DR: It is suggested that acetylator status could be used to identify susceptible individuals in potentially hazardous occupations that are more susceptible to tumour production when exposed to some N-substituted aryl compounds.

Journal ArticleDOI
TL;DR: Geographical clustering among certain racial groups suggests common aetiological factors in the pathogenesis of this disease and the finding of high titre antibody against the structural core protein of a new human C-type leukaemia virus in all tested cases from this series and data from all but one case from Japan suggest that one such factor may be viral.

Journal ArticleDOI
TL;DR: In 25 of the 43 patients with delta-positive fulminant hepatitis, serum markers indicated a primary hepatitis B infection while in the remaining 18, IgM antibody to hepatitis B core antigen was absent, indicating that hepatitis B preceded superinfection with the delta agent.

Journal ArticleDOI
TL;DR: Recognition of the most likely causes of severe pneumonia allows logical initial antibiotic treatment for such patients admitted to hospital with community-acquired illness.

Journal ArticleDOI
TL;DR: Treatment of seriously ill patients with antacids or cimetidine may encourage airway colonisation and predispose the patients to pneumonia caused by gram-negative bacilli.

Journal ArticleDOI
TL;DR: The model reconciles seroepidemiological data linking HSV to human genital cancer with the apparent difficulties in finding HSV DNA by biopsy in genital cancer.

Journal ArticleDOI
TL;DR: Three rapid interviews have considerable potential for use in the routine screening of high-risk groups, such as hospital patients and the Brief MAST, the Cage, and the Reich interviews each identified nine out of ten alcoholics.


Journal ArticleDOI
TL;DR: The clinical results can be explained by the improvement in various indices of humoral and cellular immunocompetence and the protein status in the PPN group and their deterioration in the control group during the preoperative course.

Journal ArticleDOI
TL;DR: The evidence that, in the year after myocardial infarction, beta adrenoceptor blocking drugs reduce mortality by 20--25% is supported.


Journal ArticleDOI
TL;DR: There seems to be no advantage associated with routine preoperative external biliary drainage before surgery for obstructive jaundice, and the postoperative complication rate was low and similar in both groups.