Showing papers in "The Lancet in 1984"

TL;DR: The bacteria were present in almost all patients with active chronic gastritis, duodenal ulcer, or gastric ulcer and thus may be an important factor in the aetiology of these diseases.

TL;DR: In the Whitehall study, 17 530 civil servants were classified according to employment grade, and their mortality was recorded over 10 years, showing a steep inverse relation between grade and mortality.

TL;DR: Post-transplant lymphomas or other lymphoproliferative lesions developed in 8, 4, 3, and 2 recipients, respectively, of cadaveric kidney, liver, heart, and heart-lung homografts, often without subsequent rejection of the grafts.

TL;DR: The results of the study suggest that in most cases this incontinence results from damage to the innervation of the pelvic floor muscles.

TL;DR: Serum BGP appears to be a specific marker for bone formation and can predict the histological profile in PMO and should be valuable in assessing the effects of treatments that increase bone formation.

TL;DR: It is suggested that AIDS is present in central Africa as an entity probably unrelated to the well-known endemic African KS, and an association of an urban environment, a relatively high income, and heterosexual promiscuity could be a risk factor for AIDS in Africa.

TL;DR: Regional cerebral blood flow, oxygen utilisation, fractional oxygen extraction, and cerebral blood volume were measured by positron emission tomography in thirty-two patients with internal-carotid-artery occlusion to suggest that the reduction in cerebral perfusion pressure, and hence circulatory reserve, could be most reliably predicted by the ratio of cerebralblood flow to blood volume.

TL;DR: The electrocardiographic changes observed in sleep apnoea syndrome are mediated by the autonomic nervous system; hypoxia is not the only factor involved.

TL;DR: Results confirm that moderate dietary protein restriction is an acceptable and effective way of delaying functional renal deterioration and has implications for the management of chronic renal insufficiency.

TL;DR: Thirty patients with severe refractory irritable-bowel syndrome were randomly allocated to treatment with either hypnotherapy or psychotherapy and placebo, and the difference between the two groups being highly significant.

TL;DR: The findings of this study strongly argue that the situation in central Africa represents a new epidemiological setting for this worldwide disease--that of significant transmission in a large heterosexual population.

TL;DR: In this paper, a prospective randomised study of acyclovir 10 mg/kg 8-hourly versus vidarabine 15 mg/ kg daily for 10 days was conducted.

TL;DR: There was a significantly greater improvement in depression in patients treated with nortriptyline than in a similar group of placebo-treated patients, providing an important addition to the treatments available for stroke patients.

TL;DR: It is suggested that IVIg contains anti-idiotypes against autoantibodies and may be effective in the treatment of some autoimmune diseases through idiotypic/anti-IDiotypic interactions.

TL;DR: The increased HLA-A,B,C, expression may be a means of amplifying T-cell cytotoxic responses in PBC and enables these cells to present "self antigens" to sensitised T-lymphocytes and to promote autorecognition.

TL;DR: The results up to the end of 1981 show that the odds ratio of screened vs unscreened subjects among women who died from breast cancer compared with women who did not, was 0·48 (95% confidence interval 0·23-1·00) in all age groups.

TL;DR: A new monoclonal rat anti-human lymphocyte antibody (CAMPATH-1) which lyses cells with autologous human complement was used for depletion of T lymphocytes from human bone-marrow allografts in vitro before transplantation in 11 high-risk patients.

TL;DR: The first set of injections was given within 1 h after birth and 96-100% of the infants in the three treatment groups were anti-HBs positive; the geometric mean titres of antiHBs did not differ significantly as mentioned in this paper.

TL;DR: The association between mental activity and myocardial ischaemia may operate frequently during everyday life and may explain many of the transient and symptomless electrocardiographic changes in patients with coronary disease.

TL;DR: A mass screening system for the early detection by means of a vanillylmandelic acid test of neuroblastoma in 6-month-old infants in Japan has been developed in eight districts as mentioned in this paper.

TL;DR: An outbreak of a new form of oral leucoplakia, found principally on the lateral borders of the tongue, is reported in male homosexuals in the San Francisco area, and may offer clues to the pathogenesis of other forms of oral epithelial hyperplasia and dysplasia.

TL;DR: The increased intestinal permeability to toxic "non-absorbable" compounds of less than 5000 molecular weight may account for some of the extraintestinal tissue damage common in alcoholic patients.

TL;DR: The median maternal serum alpha-fetoprotein (AFP) level at 14-20 weeks' gestation in 61 pregnancies associated with Down syndrome was 0.72 multiples of the median (MoM) value for a series of 36 652 singleton pregnancies unaffected by Down syndrome or neural-tube defect--a statistically significant reduction.

TL;DR: Dislocated or dislocatable hips were 39 times more frequent in infants who had minor signs on examination within 48 h of birth than in infants considered normal, suggesting clicking and grating of the hip are important signs which require systematic follow-up, with radiological examination at 4-6 months.

TL;DR: The component vaccine is not only potent as judged by the mouse test but is also less than one-tenth as toxic as whole-cell vaccine as judging by leucocytosis promotion, histamine sensitisation, and endotoxicity tests.

TL;DR: The likelihood of cirrhosis developing proved to be independent of duration of abuse and of daily consumption before the primary biopsy, indicating that the effect of alcohol abuse is not cumulative over time, but rather establishes conditions for the development of Cirrhosis.

TL;DR: In 1974 a non-randomised study of the effect of mass screening by physical examination and xeromammography on mortality from breast cancer was started, and of the 20 555 eligible women in the city of Utrecht born between 1911 and 1925, 14 796 attended for screening.