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Showing papers in "The Spine Journal in 2012"


Journal ArticleDOI
TL;DR: Age, sex, and race are significant risk factors for the development of low back pain necessitating treatment in an emergency department, and patients of black and white race were found to have significantly higher rates ofLow back pain.

170 citations


Journal ArticleDOI
TL;DR: The results show that modifying surface structure is sufficient to create an osteogenic environment without addition of exogenous factors, which may induce better and faster bone during interbody fusion.

168 citations


Journal ArticleDOI
TL;DR: Among Medicare beneficiaries, 30-day readmissions after elective spine surgery for degenerative conditions represent a target for improvement and both patient factors and operative techniques are associated with readmissions.

132 citations


Journal ArticleDOI
TL;DR: Normative values for anatomic parameters of sagittal pelvic alignment do not exist because the variability of the measured values is relatively high even for normal subjects but can be predictive for spinal alignment and specific spinopelvic pathologies.

124 citations


Journal ArticleDOI
TL;DR: The multivariate analysis demonstrated that age, lumbar surgery, revision surgery, and elevated surgical invasiveness are significant risk factors for unintended durotomy during spine surgery.

121 citations


Journal ArticleDOI
TL;DR: The EQ-5D is a valid and responsive QOL scale in patients with CLBP and its criterion validity, responsiveness, and minimal clinically important change (MCIC) are studied.

117 citations


Journal ArticleDOI
TL;DR: Pedicle screw with an outer cylindrical and inner conical configuration with a V-shaped thread may have maximum pullout strength, regardless of bone density.

108 citations


Journal ArticleDOI
TL;DR: Increased stiffness of multifidus in response to the physiologic range of static loads and smaller cross-sectional area was characterized in the chronic LBP condition for spinal stability, which benefits the future investigation of the neuromuscular regulating mechanism in LBP.

106 citations


Journal ArticleDOI
TL;DR: The unilateral PS group had a significantly shorter operative time, less blood loss, and reduced implant costs compared with the bilateral PS group, although hospital time was the same for double-level cases, and the average postoperative VAS, mProlo, and ODI scores improved significantly in both groups.

105 citations


Journal ArticleDOI
TL;DR: This study confirms previous reports of a higher rate of RE in ALIF procedures using rhBMP-2 and an open anterior approach to the spine, and confirms the magnitude of the RE effect may be increased with concomitant prostatic disease treatments.

103 citations


Journal ArticleDOI
TL;DR: This analysis indicates that serious adverse events can occur after the use of rhBMP-2 in spinal surgery and raises many points that surgeons may wish to consider when deciding when and how to use this product in their patients.

Journal ArticleDOI
TL;DR: Treatment of punctured rabbit intervertebral discs with AAV2-BMP2 or AAV1-TIMP1 helps delay degenerative changes, as seen on MRI, histologic sampling, serum biochemical analysis, and biomechanical testing, which supports the potential use of gene therapy for the treatment of IDD.

Journal ArticleDOI
TL;DR: Surgical invasiveness and age were significant risk factors for complications in five of the six organ systems evaluated and risk factors identified in this study can be beneficial to clinicians and patients alike when considering surgical treatment of the spine.

Journal ArticleDOI
TL;DR: Investigation of asymmetry in cross-sectional area (CSA) and fat infiltration in multifidus and other paraspinal muscles in patients with acute or subacute unilateral symptoms of radiculopathy and concordant posterolateral disc herniation found Multifidus may be particularly responsive to, or indicative of, localized lumbar disc or nerve root pathology within the first 6 weeks of symptoms, but not through CSA asymmetry on MRI.

Journal ArticleDOI
TL;DR: Thirty-three CUAs pertaining to spinal care published between 1976 and 2010 and 60 cost-utility ratios have been published on various aspects of spinal care over the last 30 years, some of which have been shown to be cost effective.

Journal ArticleDOI
TL;DR: Both treatments of OVCF showed successful clinical results at the end of the 1-year follow-up period, and prompt kyphoplasty should not be indicated in the case of a patient with OVCFs that has no risk factors for failure with conservative treatment.

Journal ArticleDOI
TL;DR: This is the first clinical report on EOS 2D/3D system and its sterEOS 3D software, documenting an excellent capability for accurate, reliable, and reproducible spinal curvature measurements.

Journal ArticleDOI
TL;DR: The results of this study indicate that the Oswestry Disability Index, SSS, and Patient Specific Functional Scale possess adequate psychometric properties to be used in the outcome assessment of patients with lumbar spinal stenosis.

Journal ArticleDOI
TL;DR: Modic changes are common MRI findings in the lumbar spines of middle-aged white men, with Type 2 MCs predominating and the presence and size ofMCs are clearly related to age, suggesting that aging or associated factors may play an essential role in the pathogenesis of MCs.

Journal ArticleDOI
TL;DR: Routine insertion of the lateral mass screw via the C1 posterior arch was feasible in even those with a small posterior arch, ponticulus posticus, or persistent first intersegmental artery, and was preventable by mobilization before screw insertion.

Journal ArticleDOI
TL;DR: Even after adjusting for patient demographics and comorbidity, a large variation in reoperation rates across hospitals and surgeons after lumbar discectomy, a relatively simple spinal procedure is observed, suggesting uncertainty about indications for repeat surgery, variations in perioperative care, or variations in quality of care.

Journal ArticleDOI
TL;DR: There is a significant increase in anterior cervical soft-tissue swelling after anterior cervical discectomy and fusion and the width of prevertebral soft-Tissue does not correlate with postoperative dysphagia.

Journal ArticleDOI
TL;DR: Single-stage PDS with or without corpectomy effectively improved the functional status of patients with MSCC of the thoracic spine and also afforded the patients to have more chances of postoperative adjuvant therapy, which was significant for patients' survival.

Journal ArticleDOI
TL;DR: A 2.1% rate of repeat surgery within 2 years of a single-level ACDF performed during routine clinical practice is identified, which is lower than that reported in the control arm of the Prestige, ProDisc-C, Bryan, Kineflex|C, and Mobi-C FDA trials.

Journal ArticleDOI
TL;DR: The incidence of symptomatic ASD after cervical TDR is 3.1% annually regardless of the patient's age, sex, smoking habits, and design of the TDR device.


Journal ArticleDOI
TL;DR: In this article, the effects of small and large annulus fibrosus injury on intervertebral disc (IVD) degeneration were investigated using bovine motion segments.

Journal ArticleDOI
TL;DR: Both MTT and SPWT can quantify walking abilities in NC but neither test demonstrated adequate external responsiveness, and neither test should be considered as a meaningful substitution for disease-specific measures of function.

Journal ArticleDOI
TL;DR: An overview of the current understanding of epidemiology, possible causes, and relative prognosis of spine-area pain syndromes in military personnel is provided, including a discussion of various treatment options available in theaters of operation.

Journal ArticleDOI
TL;DR: NDI is the most valid and responsive measure of improvement after surgery for neck and arm pain and NDI are poor substitutes for NDI when measuring effectiveness of care in registry efforts.