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JournalISSN: 0041-008X

Toxicology and Applied Pharmacology 

Elsevier BV
About: Toxicology and Applied Pharmacology is an academic journal published by Elsevier BV. The journal publishes majorly in the area(s): Toxicity & Apoptosis. It has an ISSN identifier of 0041-008X. Over the lifetime, 15182 publications have been published receiving 624223 citations. The journal is also known as: TAAP.

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Journal ArticleDOI
TL;DR: It can be anticipated that a considerable proportion of the non-smoking adult population has urinary cadmium concentrations of 0.5 microg/g creatinine or higher in non-exposed areas, and for smokers this proportion is considerably higher, which implies no margin of safety between the point of departure and the exposure levels in the general population.

1,954 citations

Journal ArticleDOI
TL;DR: The role of these four ABC transporter proteins in protecting tissues from a variety of toxicants is discussed and species variations in substrate specificity and tissue distribution of these transporters are addressed since these properties have implications for in vivo models of toxicity used for drug discovery and development.

1,327 citations

Journal ArticleDOI
TL;DR: It is demonstrated that only ultrafine polystyrene particles induced a significant increase in cytosolic calcium ion concentration and experiments using dichlorofluorescin diacetate demonstrated greater oxidant activity of the ultrafine particles, which may explain their activity in these assays.

1,181 citations

Journal ArticleDOI
TL;DR: The results suggest that carbon nanotubes are potentially toxic to humans and that strict industrial hygiene measures should to be taken to limit exposure during their manipulation.

1,055 citations

Journal ArticleDOI
TL;DR: In the clinic, artificial lamps emitting UVB and UVA radiation in combination with chemical drugs are used in the therapy of many skin diseases including psoriasis and vitiligo, and although such therapy is beneficial, it is accompanied with undesirable side effects.

1,045 citations

No. of papers from the Journal in previous years