Showing papers in "Transfusion Medicine Reviews in 2000"

TL;DR: It is reasonable to conclude that individuals belonging to the different blood groups are not equally viable, and it is possible that in some conditions, infectious or otherwise, they would depart from their normal frequencies, indicating that persons of a particular blood group are unduly susceptible to the disease in question.

TL;DR: It was not until the 1960s that clinical studies showed that therapeutic platelet transfusions decreased fatal hemorrhagic complications in thrombocytopenic patients and that prophylactic plateel transfusions reduced episodes of bleeding.

TL;DR: The term T for Thomsen-Friedenreich specificity precedes all these other 'T ' designations by decades and therefore should not be abandoned.

TL;DR: The Kell/XK complex is not limited to erythroid tissues and may have multiple physiological roles, whereas the other protein component, Kell, is an enzyme whose principal known function is the production of a potent bioactive peptide, ET-3.

TL;DR: Because of their easy accessibility, RBCs will continue to be used as a major tool in the investigation of the causative agents for disease, whether they be viral, bacterial, or parasitic in nature.

TL;DR: The clinical presentation and course is variable and ranges from asymptomatic thrombocytopenia to intracerebral bleeding and death and it is well documented that FMAIT may be caused by maternal alloantibodies against fetal human platelet antigens (HPA).

TL;DR: The small number of studies done on the covalent modification of RBC with PEG, or PEG-derivatives, suggests that the immunocamouflage of intact cells significantly reduces the antigenicity and immunogenicity of the foreign cell.

TL;DR: It is found that allogeneic blood transfusion could enhance the acceptance of allografts and has prompted extensive investigation on the possible immunologic mechanisms for this intriguing phenomenon.

TL;DR: If a decision were to be made to implement universal WBC reduction in the United States, such a policy would probably be introduced not with an intent to prevent the transmission of new variant Creutzfeldt-Jakob disease, but to reap other potential benefits from WBC reduce.

TL;DR: Because the immune system of the mammalian fetus and neonate is not fully developed, this transfer is essential to the survival of the individual as well as the species.

TL;DR: The characterization of the molecular genetics of most of the 25 blood group systems, combined with the study of null phenotypes, has expanded the understanding of the structure and function of the membrane components carrying blood group antigens.

TL;DR: The main current treatments for WAIHA are corticosteroids, splenectomy, and immunosuppressive drugs, with a wide variety of therapies employed with varying success in cases resistant to the three approaches.

TL;DR: The structure, tissue distribution, and ligand-binding properties of the different CAMs that are expressed on erythroid cells are described, and their function in erythropoiesis is discussed.