Showing papers in "Trends in Biotechnology in 2006"

TL;DR: This review gives an overview of the new technologies required and the advances achieved in recent years to bring lignocellulosic ethanol towards industrial production.

TL;DR: A brief discussion of laccases, a group of enzymes that work with air and produce water as the only by-product, and their uses span from the textile to the pulp and paper industries, and from food applications to bioremediation processes.

TL;DR: Early, uncontrolled, non-randomized clinical research, applying fresh adipose-derived cells into a cranial defect or undifferentiated ADSCs into fistulas in Crohn's disease, has shown healing and an absence of side effects.

TL;DR: Practical approaches that have been adopted to make the biosurfactant production process economically attractive include the use of cheaper raw materials, optimized and efficient bioprocesses and overproducing mutant and recombinant strains for obtaining maximum productivity.

TL;DR: The progress made in the exploitation of the plasmon resonance of gold nanoparticles in photo-thermal therapeutic medicine is reviewed.

TL;DR: The therapeutic use of autologous platelet-rich plasma is highlighted and some of the obstacles and challenges that need to be addressed to maintain progress in this field are discussed.

TL;DR: The scope and potential of IVC in areas such as in vitro evolution of proteins and RNAs, cell-free cloning and sequencing, genetics, genomics, and proteomics are described.

TL;DR: The successful clinical application of polymer-protein conjugates and promising results arising from clinical trials with polymer-bound chemotherapy have provided a firm foundation for more sophisticated second-generation constructs that deliver the newly emerging target-directed anticancer agents.

TL;DR: This article will discuss issues, pinpointing specific new advances in recombinant DNA techniques amenable to future biocatalyst development, in addition to drawing the attention of the biotechnology community to the active pursuit and development of environmentalBiocatalysis, from remediation with enzymes to novel green processes.

TL;DR: Recent data suggest that these protein aggregates might be a reservoir of alternative conformational states, their formation being no less specific than the acquisition of the native-state structure.

TL;DR: Recent strategies for reducing or eliminating acetate are reviewed, including approaches that optimize the protein production process as well as those that involve modifying the host organism itself.

TL;DR: 2A functions in all the eukaryotic systems tested to date and has already been applied, with great success, to a broad range of biotechnological applications: from plant metabolome engineering to the expression of T-cell receptor complexes, monoclonal antibodies or heterodimeric cytokines in animals.

TL;DR: By adding meaning to text, text mining techniques produce a more structured analysis of textual knowledge than simple word searches, and can provide powerful tools for the production and analysis of systems biology models.

TL;DR: It is hoped that the wide range of scientists, clinicians and biotechnologists currently researching or putting phages to practical use are able to pool their knowledge and expertise and thereby accelerate progress towards further development in this exciting field of biotechnology.

TL;DR: Electrochemical and enzymatic approaches for the replacement or regeneration of NAD(P)H have been developed, enabling the more cost-effective use of P450 enzymes.

TL;DR: Techniques for imprint lithography, categorized as either 'molding and embossing' or 'transfer printing', will be discussed in the context of microarrays for genomics, proteomics and tissue engineering.

TL;DR: Rapidly increasing understanding of membrane protein insertion, folding and degradation means that membrane protein overexpression can be more rationalized, both at the level of the overeexpression host and the overexpressed membrane protein.

TL;DR: It is proposed to take FT-IR imaging into consideration for the development of new molecular histopathology tools, to analyze cerebral tumor exereses in delays compatible with neurosurgery.

TL;DR: The need to consider post-synthesis and/or post-secretion instability and degradation mechanisms contributing to low foreign protein yield is highlighted and a range of remedial strategies aimed at minimizing foreign protein degradation and loss are outlined.

TL;DR: In this paper, the authors used molecular genetic mapping of quantitative trait loci (QTL) of several complex traits that are important in breeding to enhance the prediction of phenotypes from genotypes for cereal breeding.

TL;DR: In this paper, the past and future roles of molecular ecophysiology and genomics in the development of wastewater microbiology as an important subdiscipline of microbial ecology are discussed.

TL;DR: This work uses molecular genetic mapping of quantitative trait loci (QTL) of several complex traits that are important in breeding to enhance the prediction of phenotypes from genotypes for cereal breeding.

TL;DR: The present article provides an overview of the microcarrier culture system, its utility as an in vitro research tool and its potential applications in tissue engineering, particularly in the repair of cartilage and bone.

TL;DR: A new strategy for identifying protein-protein interactions that would be particularly promising targets for modulation by small molecules is developed, based on intrinsically disordered protein, which has the potential to increase significantly the discovery rate for new molecule entities.

TL;DR: This review highlights some of the significant progress made in the scale-up of the hairy root cultures in the past three years and discusses the potential implications of that research.

TL;DR: Two different methods for obtaining promoter libraries are described and compared, whereby the individual promoters might deviate either in their spacer sequences or bear slight deviations from the consensus sequence of a vegetative promoter.

TL;DR: The recent advances of enzyme-immobilized microchannel reactors; fundamental techniques for micro enzyme-reactor design and important applications of this multidisciplinary technology in chemical processing are also included in this topics.

TL;DR: To enable the evaluation of the effects of immunogenicity on safety and efficacy, the authors have consolidated recommendations from the regulatory guidelines, and present current approaches and future directions for the assessment of Immunogenicity.

TL;DR: NMR spectroscopy is described as a highly effective tool for unraveling the atomic details of weak PPIs and has the potential to look into a wide variety of biologically important weak PPI at the detailed molecular level, thereby facilitating a thorough view of how proteins function in living cells.

TL;DR: The zebrafish is a versatile and well-characterized model with applications in many fields of study and is increasingly used in toxicogenomics to analyze the effects of toxins and pollutants in the environment, and for creating biomonitors that emit alarm signals when a toxic compound is detected.