Journal•ISSN: 1050-1738
Trends in Cardiovascular Medicine
Elsevier BV
About: Trends in Cardiovascular Medicine is an academic journal published by Elsevier BV. The journal publishes majorly in the area(s): Medicine & Heart failure. It has an ISSN identifier of 1050-1738. Over the lifetime, 2156 publications have been published receiving 74577 citations. The journal is also known as: TCM.
Papers published on a yearly basis
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TL;DR: The metabolic syndrome is a multiplex risk factor for atherosclerotic cardiovascular disease and type 2 diabetes and at times, drug therapies or bariatric surgery may be required to control more overt risk factors.
570 citations
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TL;DR: The activation of endothelial cells at atherosclerotic lesion-prone sites in the arterial tree results in the up-regulation of cell adhesion molecules and chemokines, which mediate the recruitment of circulating monocytes.
484 citations
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TL;DR: Evidence is presented suggesting that the pharmacologic manipulation of the RISK pathway at the time of reperfusion may enable one to harness the powerful cardioprotective benefits of both ischemic preconditioning and postconditioning, and provide a novel approach toCardioprotection.
453 citations
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TL;DR: PPARalpha not only serves a critical role in normal cardiac metabolic homeostasis, but alterations in PPARalpha signaling likely contribute to the pathogenesis of a variety of disease states.
450 citations
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TL;DR: The oxidation hypothesis is still viable, but a great deal needs to be learned in order to design the appropriate clinical trials to properly test the importance of oxidation in the pathogenesis of atherosclerosis in humans.
430 citations