Journal•ISSN: 1471-4914
Trends in Molecular Medicine
Elsevier BV
About: Trends in Molecular Medicine is an academic journal published by Elsevier BV. The journal publishes majorly in the area(s): Medicine & Biology. It has an ISSN identifier of 1471-4914. Over the lifetime, 2224 publications have been published receiving 191721 citations.
Topics: Medicine, Biology, Cancer, Immune system, Gene
Papers published on a yearly basis
Papers
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TL;DR: The role of NF-κB in TLR signaling pathways has been discussed in this article, where the authors review recent progress in their understanding of the role and potential implications for molecular medicine.
1,822 citations
TL;DR: The potential applications of microRNAs for the clinical assessment of patient outcome in cancer, as well as in cancer monitoring and therapy are reviewed.
1,680 citations
TL;DR: Analysis of keap1-knockout mice provides solid evidence that Keap1 acts as a negative regulator of Nrf2 and as a sensor of xenobiotic and oxidative stresses.
1,529 citations
TL;DR: DNA damage-triggered signaling and execution of apoptosis is cell-type- and genotoxin-specific depending on the p53 (p63 and p73) status, death-receptor responsiveness, MAP-kinase activation and, most importantly, DNA repair capacity.
1,382 citations
TL;DR: By understanding the complex, multistep and multifactorial differentiation pathway from MSC to functional tissues, it might be possible to manipulate MSCs directly in vivo to cue the formation of elaborate, composite tissues in situ.
1,161 citations