Showing papers in "Ukraïns'kyĭ biokhimichnyĭ zhurnal in 1963"

[anti-radiation and anti-oxidation properties of some polyphenols].

Abstract: The anti-oxidation activity of a number of polyphenols and ascorbic acid was assayed by their capacity for retaining accumulation of peroxides in irradiated oleic acid. The anti-radiation efficacy of the preparations was determined by the survival of mice irradiated by 600 r (minimam absolutely lethal dose of radiation) to which the preparations were administered on a phosphate buffer at pH 7.2 thirty minutes before irradiation or immediately afterwards. The average lifetime of the animals that died was also taken into consideration. All investigated substances inhibited fat oxidation to a lesser or greater extent. A reliable anti-radiation effect, both defensive and therapeutic, is possessed by eglantine extract, galascorbin and tanin; rutin is less reliable. The correlation between the antioxidation and the anti-radiation effect of polyphenols was not elucidated. (auth)