Showing papers in "Urology in 2003"
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TL;DR: The standardisation of terminology in lower urinary tract function: report from the standardisation sub-committee of the International ContinenceSociety.
4,293 citations
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TL;DR: The incidence of prostate cancer increased sharply after the introduction of widespread screening for prostate-specific antigen (PSA), although rates have now returned to levels seen before that time, and PSA screening has been associated with a shift toward diagnosis of earlier-stage disease.
596 citations
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TL;DR: A simple, watertight, running Laparoscopic suture technique for accomplishing the urethrovesical anastomosis during laparoscopic radical prostatectomy and no clinically evident clinical bladder neck contractures resulted.
488 citations
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TL;DR: Despite national variations in prevalence, uniform associations were found between ED and medical conditions and lifestyle habits, and inversely associated with education, physical activity, and alcohol drinking.
458 citations
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TL;DR: UBBTMs can be used for follow-up of low-grade/stage tumors but should not replace cystoscopy, and all UBBTMs have better sensitivity than cytology and could potentially replace routine cytology during patient follow- up.
407 citations
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TL;DR: The androgen receptor (AR) signalling pathway plays a crucial role in both early development as well as in late progression of the disease, and germ-line and somatic genetic alterations in the AR gene have been demonstrated in prostate cancer patients.
375 citations
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TL;DR: Doxazosin was effective in improving urinary symptoms and urinary flow rate in men with benign prostatic hyperplasia, and was more effective than finasteride alone or placebo.
355 citations
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TL;DR: The availability of dutasteride, the first dual (Type 1/Type 2) 5alpha-reductase inhibitor, offers the opportunity for rapid and consistent inhibition of DHT.
343 citations
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TL;DR: Prevalence, incidence, natural history, and the variations that may be related to race and ethnicity are discussed, focusing on epidemiologic population comprising community-dwelling women who are not institutionalized.
322 citations
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TL;DR: Tadalafil 20 mg is an effective and well-tolerated treatment for ED that has a period of responsiveness of up to 36 hours and the incidences of four treatment-emergent adverse events were significantly greater in the tadalafils group than in the placebo group.
300 citations
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TL;DR: OXY-TDS improves systemic safety with regard to anticholinergic side effects and TOL-LA are effective and comparable treatments for patients with urge and mixed incontinence.
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TL;DR: The conservative estimates of the total cost of OAB were comparable to those of osteoporosis and gynecologic and breast cancer and quality-of-life issues must be taken into account to gain a better understanding of this condition.
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TL;DR: The International Continence Society has recommended the use of the terms overactive bladder syndrome (OAB) and detrusor overactivity, believing that these terms are more intuitive and will make it easier for patients and physicians alike to understand.
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TL;DR: A PSA value greater than 0.2 ng/mL is an appropriate cutpoint to define PSA recurrence after RP, and PSA and biopsy Gleason score were significant predictors of biochemical failure, regardless of the definition of failure used.
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TL;DR: Patients with biochemical recurrence after radical prostatectomy have a low probability of a positive bone scan (9.4%) or a positive CT scan (14.0%) within 3 years of biochemicalRecurrence.
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TL;DR: Botulinum toxin injected into the prostate seems to be a promising approach for the treatment of benign prostatic hyperplasia and is safe, effective, and well-tolerated.
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TL;DR: Physiologic effects, including gynecomastia, changes in body composition, and changes in lipids, are less commonly recognized as side effects of ADT and should be incorporated into routine practice.
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TL;DR: Low-dose, vaginally administered estrogens have a role in the treatment of urogenital atrophy in postmenopausal women and appear to be as effective as systemic preparations.
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TL;DR: New results show that at least some high-grade prostatic intraepithelial neoplasias and early adenocarcinomas appear to arise from proliferative inflammatory atrophy (PIA), and AMACR may be an important new marker of prostate cancer, and its use in combination with p63 staining may provide the basis for an improved method for identification of prostatecancer.
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TL;DR: The 12/14F access sheath provides for maximum flow of irrigant while maintaining a low intrarenal pelvic pressure, and is recommended for flexible ureteroscopy use.
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TL;DR: Antimuscarinic agents are effective for treatment of the overactive bladder, which is characterized by urge, frequency, urge incontinence, and nocturia (ie, LUTS), which suggests that muscarinic receptors are involved in the pathogenesis of LUTs, and there is recent evidence implicating purinergic receptors.
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TL;DR: A 21-sample needle biopsy procedure for prostate cancer in patients with elevated serum prostate-specific antigen and/or abnormal digital rectal examination findings increased the cancer detection rate relative to a 6-sample procedure, without increasing morbidity.
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TL;DR: The two approaches showed similar outcomes regarding continence and erectile function 1 year after surgery, however, the recovery of nocturnal continence seemed to occur earlier after the laparoscopic approach.
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TL;DR: Results indicate that exposure to CCl4 leads to renal damage in rats and betaine exerts an improvement on nephrotoxic effects of CCl 4.
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TL;DR: For both node-negative and node-positive patients, improved survival and a reduced local recurrence rate was associated with negative surgical margins and a greater number of lymph nodes removed.
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TL;DR: Urethral denervation resulted in near-total abolishment of the skeletal muscle and partial impairment of smooth muscle contractility and MDPC-mediated cellular urethral myoplasty warrants additional investigation as a new method to treat stress urinary incontinence.
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TL;DR: Diabetic patients with UA stones share a key feature of those with GD, namely the passage of unusually acid urine, but not the low fractional excretion of urate.
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TL;DR: Guidelines for the management of prostate cancer issued by the National Comprehensive Cancer Network provide a basis for rational treatment decisions and describe the appropriate use of observation ("watchful waiting") versus active intervention in certain patients.
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TL;DR: Six months of alfuzosin therapy for CP/CPPS is safe and well tolerated and results in a modest, but statistically significant, improvement in the NIH-CPSI, particularly in the pain domain, compared with placebo and standard/traditional treatment.