Journal•ISSN: 1537-1891
Vascular Pharmacology
Elsevier BV
About: Vascular Pharmacology is an academic journal published by Elsevier BV. The journal publishes majorly in the area(s): Medicine & Endothelium. It has an ISSN identifier of 1537-1891. Over the lifetime, 1775 publications have been published receiving 50540 citations. The journal is also known as: Vascul Pharmacol.
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TL;DR: In this paper, a review of tight junction regulation in the blood-brain barrier is presented, which includes claudins, occludin, ZO-1, zo-2, Zo-3, cingulin and 7H6.
986 citations
TL;DR: This review will focus on the main mechanisms involved in the onset of endothelial dysfunction, with particular focus on inflammation and aberrant ROS production and on their relationship with classical and non-classical cardiovascular risk factors, such as hypertension, metabolic disorders, and aging.
707 citations
TL;DR: This review aims to provide an overview of the links between oxidative stress, vascular inflammation, endothelial dysfunction and cardiovascular risk factors, importantly focusing on blood pressure regulation and atherosclerosis.
701 citations
TL;DR: Evidence for the opposing effects of Rho and Rac GTPase signalling is presented and links between them and other key signalling molecules such as cyclic AMP, cyclic GMP, phosphatidylinositide 3-kinases (PI3Ks), mitogen-activated protein kinases (MAPKs, and protein kinase C (PKCs) are discussed.
455 citations
TL;DR: The mechanisms by which VEGFs stimulate increased vascular permeability to water and large molecular weight proteins and vasodilatation are outlined and some of the difficulties in interpreting data from VEGF studies are discussed due to the conflicting and synergistic effects of these actions.
401 citations