14-3-3 proteins: an important regulator of autophagy in diseases.
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Cites background from "14-3-3 proteins: an important regul..."
...In the majority of cases, 14-3-3 proteins bind specifically to motifs containing phosphoserine or phosphothreonine, and thus protein-protein interactions involving 14-3-3 proteins are typically phosphorylation dependent [74]....
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Cites background from "14-3-3 proteins: an important regul..."
...Multiple studies have shown that 14-3-3 proteins play important roles in the regulation of autophagy [20, 30, 31]....
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...A significant reduction in Beclin-1 expression correlating with positive regulation of autophagy has been observed in U20S cell lines response expressing inducible or transient siRNA against 14-3-3t [30]....
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References
4,529 citations
"14-3-3 proteins: an important regul..." refers background in this paper
...The formation of double-membrane autophagosomes involves the following steps: induction, nucleation, elongation, and formation a complete isolation membrane [9]....
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3,721 citations
"14-3-3 proteins: an important regul..." refers background in this paper
...Autophagy is classified into three subtypes: macroautophagy, microautophagy and chaperone-mediated autophagy [2]....
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3,384 citations
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"14-3-3 proteins: an important regul..." refers background in this paper
...Ravikumar et al found that in fly and mouse models of Huntington’s disease, the inhibition of mTOR induces autophagy and eliminates the accumulation of polyglutamine [12]....
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2,168 citations
"14-3-3 proteins: an important regul..." refers background in this paper
...4740 Am J Transl Res 2017;9(11):4738-4746 siRNA had the opposite effect [17]....
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