2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer.
Citations
35,190 citations
7,525 citations
2,924 citations
2,409 citations
1,988 citations
References
1,198 citations
"2015 American Thyroid Association M..." refers background in this paper
...The BRAF V600E mutation is found in ~80% of these tumors (156;466)....
[...]
1,195 citations
1,171 citations
"2015 American Thyroid Association M..." refers background or result in this paper
...Benefit has been demonstrated in the form of improved progression free survival (delay in time to disease progression or death) in three randomized, double-blinded, placebo-controlled, clinical trials (vandetanib (1033); sorafenib (1013); lenvatinib (1034)....
[...]
...241 therapy of progressive, radioiodine-refractory, metastatic DTC, patients whose tumors contained the BRAF V600E mutation who were randomized to the placebo treatment arms experienced similar progression-free survival compared with those whose tumors did not harbor a BRAF mutation (1013;1014)....
[...]
...249 the basis of improved progression-free survival when compared to placebo (1013;1034)....
[...]
1,145 citations
"2015 American Thyroid Association M..." refers background in this paper
...Adverse effects of TSH suppression may include the known consequences of subclinical thyrotoxicosis, including exacerbation of angina in patients with ischemic heart disease, increased risk for atrial fibrillation in older patients (751), and increased risk of osteoporosis in postmenopausal women (748;752-754)....
[...]
1,071 citations