23Na Magnetic Resonance Imaging-Determined Tissue Sodium in Healthy Subjects and Hypertensive Patients
Citations
345 citations
Cites background from "23Na Magnetic Resonance Imaging-Det..."
...org Volume 123 Number 7 July 2013 2811 magnetic resonance imaging techniques to make Na+ storage visible in animals and patients (67, 68) and have shown that essential hypertension in humans is paralleled by tissue Na+ storage (69)....
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314 citations
300 citations
Cites background from "23Na Magnetic Resonance Imaging-Det..."
...myotonic dystrophy [358,359], Duchenne muscular dystrophy [360,361], hypertension [362], severe kidney disease [363], heart failure [364], and muscular channelopathies [365–367]....
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266 citations
Cites background from "23Na Magnetic Resonance Imaging-Det..."
...The emerging magnetic resonance imaging–based techniques that directly detect Na+ in tissues [81] have recently provided confirmation and further evidence about the compartmentalized sodium storage in humans, also in relation to cardiovascular morbidities [82]....
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251 citations
References
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"23Na Magnetic Resonance Imaging-Det..." refers background in this paper
...Mendelian forms of hypertension have underscored the role of salt intake in the development of hypertension.(2) Clinicians have advised patients in terms of their dietary intake and have relied on 24 hour urine collections to verify dietary compliance....
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838 citations
"23Na Magnetic Resonance Imaging-Det..." refers background in this paper
...Our earlier ashing studies indicated that the bone storage is minimal, and that instead large quantities are stored in the skin.(5,6) The skin is abundant in branching glycosaminoglycans that possess a strong negative charge, largely because of their sulfate content....
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...We showed recently that signaling mechanisms exist in skin that control skin electrolyte storage.(6) When these mechanisms are perturbed, salt-sensitive hypertension results....
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509 citations
"23Na Magnetic Resonance Imaging-Det..." refers background in this paper
...The issue is important, as salt-sensitivity portends an earlier death.(4) Na is bound to negatively charged proteoglycans that are very abundant in the skin, the body’s largest organ....
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328 citations
"23Na Magnetic Resonance Imaging-Det..." refers methods in this paper
...5×5 mm(3)), as described by other investigators.(8) Here, the 10 mmol/L NaCl tube served as a calibration standard for tissue water....
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