Journal ArticleDOI
3D Graphene Oxide–Polymer Hydrogel: Near-Infrared Light-Triggered Active Scaffold for Reversible Cell Capture and On-Demand Release
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TLDR
An active cell scaffold based on a graphene-polymer hydrogel has been successfully fabricated that can efficiently capture cells not only through the bioadhesive ligand RGD but also through on-demand release of cells with an NIR light stimulus.Abstract:
An active cell scaffold based on a graphene-polymer hydrogel has been successfully fabricated. The macroporous hydrogel can efficiently capture cells not only through the bioadhesive ligand RGD but also through on-demand release of cells with an NIR light stimulus. The latter process shows better dynamic control over cells than traditional passive-hydrogel-based cell depots.read more
Citations
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A Novel Wound Dressing Based on Ag/Graphene Polymer Hydrogel: Effectively Kill Bacteria and Accelerate Wound Healing
Zengjie Fan,Bin Liu,Jinqing Wang,Songying Zhang,Qianqian Lin,Peiwei Gong,Limin Ma,Shengrong Yang +7 more
TL;DR: In this article, a series of hydrogels are prepared by crosslinking of Ag/graphene composites with acrylic acid and N,N'-methylene bisacrylamide at different mass ratios.
Journal ArticleDOI
Nanocomposite Hydrogels: 3D Polymer–Nanoparticle Synergies for On-Demand Drug Delivery
TL;DR: This review highlights the latest advances in nanocomposite hydrogels as drug delivery vehicles and the inclusion/incorporation of nanoparticles in three-dimensional polymeric structures is an innovative means for obtaining multicomponent systems with diverse functionality within a hybrid hydrogel network.
Journal ArticleDOI
The design of reversible hydrogels to capture extracellular matrix dynamics
TL;DR: The extracellular matrix (ECM) is a dynamic environment that constantly provides physical and chemical cues to embedded cells, and emerging trends include the use of molecular photoswitches or biomolecule hybridization to control polymer chain conformation.
Journal ArticleDOI
Bioactive nanoengineered hydrogels for bone tissue engineering: a growth-factor-free approach.
Janet R. Xavier,Teena Thakur,Prachi Desai,Manish K. Jaiswal,Nick Sears,Elizabeth Cosgriff-Hernandez,Roland Kaunas,Akhilesh K. Gaharwar +7 more
TL;DR: These results demonstrate the multiple functions of nanosilicates conducive to the regeneration of bone in nonunion defects, including increased network stiffness and porosity, injectability, and enhanced mineralized matrix formation in a growth-factor-free microenvironment.
Journal ArticleDOI
Multifunctional Stimuli-Responsive Hydrogels with Self-Healing, High Conductivity, and Rapid Recovery through Host–Guest Interactions
TL;DR: This work presents self-healing conductive hydrogels based on β-cyclodextrin, N-isopropylacrylamide, NIPAM, multiwalled carbon nanotubes and nanostructured polypyrrole, which exhibit high conductivity, self- healing property, flexible and elastic mechanical property and rapid stimuli-responsive property both to temperature and near-infrared (NIR)-light together.
References
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Journal ArticleDOI
New perspectives in cell adhesion : RGD and integrins
TL;DR: Together, the adhesion proteins and their receptors constitute a versatile recognition system providing cells with anchorage, traction for migration, and signals for polarity, position, differentiation, and possibly growth.
Journal ArticleDOI
Band gap fluorescence from individual single-walled carbon nanotubes.
Michael J. O'Connell,Sergei M. Bachilo,Chad B. Huffman,Valerie C. Moore,Michael S. Strano,Erik H. Haroz,Kristy L. Rialon,Peter J. Boul,William H. Noon,Carter Kittrell,Jianpeng Ma,Jianpeng Ma,Robert H. Hauge,R. Bruce Weisman,Richard E. Smalley +14 more
TL;DR: At pH less than 5, the absorption and emission spectra of individual nanotubes show evidence of band gap–selective protonation of the side walls of the tube, which is readily reversed by treatment with base or ultraviolet light.
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A clearer vision for in vivo imaging.
TL;DR: Progress continues in the development of smaller, more penetrable probes for biological imaging, and the number of probes in this line of research has increased.
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Hydrogels in regenerative medicine
Brandon V. Slaughter,Shahana S. Khurshid,Omar Z. Fisher,Ali Khademhosseini,Nicholas A. Peppas +4 more
TL;DR: The properties of hydrogels that are important for tissue engineering applications and the inherent material design constraints and challenges are discussed.