3D printing for the design and fabrication of polymer-based gradient scaffolds.
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Cites background or methods from "3D printing for the design and fabr..."
...Typically, a scaffold for wound healing can assist one of the following functions [61]: (i) It supports the delivery and retention of cells and different biochemical factors; (ii) It lets cells interact and connect by facilitating proper cell attachment and migration; (iii) It permits the flow of vital cell nutrients and released products; (iv) It modifies cells behavior by exerting mechanical and biological stimuli; (v) It mimics the ECM-like microenvironment in 3D space [62]....
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...categorized these techniques into conventional and advanced (Table 5) [62]....
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References
12,204 citations
"3D printing for the design and fabr..." refers background in this paper
...While highly porous scaffolds permit the ingression of tissue within a construct, it has been shown that the substrate stiffness directs the differentiation and migration of mesenchymal stem cells into different cell types such as myoblasts, osteoblast, and neurons [55]....
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4,914 citations
"3D printing for the design and fabr..." refers background in this paper
...Highly porous biomaterials aid in de novo tissue regeneration by 1) allowing mass transport of nutrients and wastes, 2) providing a large surface area for cellular attachment and growth, 3) permitting vascularization of the implant, and 4) facilitating mechanical interlocking with the adjacent tissue [41, 42]....
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4,841 citations
"3D printing for the design and fabr..." refers background or methods in this paper
...Overall, inkjet bioprinters are inexpensive, create high-resolution patterns in the range of 20-100 μm at speeds in the range of 1-10,000 droplets/s and can introduce concentration gradients of cells and/or bioactive molecules throughout the 3D construct [9, 25]....
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...concern by using a piezoelectric actuator to eject small droplets from the nozzle [9]....
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...tissue engineering, 3D printing has been applied to virtually all tissues in the body and has even been utilized to fabricate whole organs [9]....
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...Similar to inkjet printers, a liquid prepolymer solution is deposited in one continuous strand or single dots to generate the desired structure [9]....
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3,487 citations
"3D printing for the design and fabr..." refers background in this paper
...Consideration of a tissue-engineered scaffold’s architecture on the macro-, micro- and nanoscale is crucial for proper nutrient and waste transport, cellular interactions, mechanical stability, and ultimately functional tissue formation [1]....
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2,195 citations