Book ChapterDOI
3D Printing Technology of Polymer Composites and Hydrogels for Artificial Skin Tissue Implementations
Jenifer Joseph,Kalim Deshmukh,Tran Thanh Tung,K. Chidambaram,S. K. Khadheer Pasha +4 more
- pp 205-233
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TLDR
The combination of polymer composites, hydrogels and 3D printing contributes in acquiring a new, efficient, cost-effective and enhanced biocompatible biological organ.Abstract:
Today, the need for tissue and organ transplant has occupied the centre stage in the field of biomedical engineering. The requirement and the replacement ratio increase drastically where the supply was not met by the demand due to the lack of donors, poor biocompatibility of tissues from donors that boycotts the transplant itself. On the other hand, from the advancement in technology, it is possible to replace natural tissues with some polymeric hydrogels whose mechanical behaviour and biocompatibility resembles the natural tissues. Additionally, hydrogels are one of the effective materials that offer an aqua environment with enriched oxygen and nutrition content that a biological cell needs. Further, three-dimensional (3D) printing, a manufacturing technique where the biomedical organs are fussed with materials such as plastic, ceramics, liquids, powder, living cell etc. in such a way that it provides a 3D object in the micron-scale resolution. Therefore, the combination of polymer composites, hydrogels and 3D printing has its application in skin bioprinting and tissue engineering. Thus, it contributes in acquiring a new, efficient, cost-effective and enhanced biocompatible biological organ.read more
Citations
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Journal ArticleDOI
Nanocomposite scaffolds for accelerating chronic wound healing by enhancing angiogenesis.
Hamed Nosrati,Reza Aramideh Khouy,Ali Nosrati,Mohammad Khodaei,Mehdi Banitalebi-Dehkordi,Korosh Ashrafi-Dehkordi,Samira Sanami,Zohreh Alizadeh +7 more
TL;DR: In this paper, the role of nanobiomaterials in angiogenesis and scaffold-based tissue engineering approaches for accelerated wound healing based on improved Angiogenesis is discussed.
Journal ArticleDOI
Methods and materials for additive manufacturing: A critical review on advancements and challenges
TL;DR: A critical review of the state of art materials in the categories such as metals and alloys, polymers, ceramics, and biomaterials are presented along with their applications, benefits, and the problems associated with the formation of microstructures, mechanical properties, and controlling process parameters.
Journal ArticleDOI
3D-printed microneedles in biomedical applications
Sajjad Rahmani Dabbagh,Misagh Rezapour Sarabi,Reza Rahbarghazi,Emel Sokullu,Ali K. Yetisen,Savas Tasoglu +5 more
TL;DR: The development of 3D-printed microneedles has enabled the evolution of pain-free controlled release drug delivery systems, devices for extracting fluids from the cutaneous tissue, biosignal acquisition, and point-of-care diagnostic devices in personalized medicine as discussed by the authors.
Journal ArticleDOI
Composition and design of nanofibrous scaffolds of Mg/Se- hydroxyapatite/graphene oxide @ ε-polycaprolactone for wound healing applications
TL;DR: In this paper, the structural properties of both powder and nanofibrous scaffolds were characterized using XRD, while the morphological behavior was investigated via FESEM, and the calculated lattice parameters indicated that HAP tends to grow in the c-axis to form rod shapes which were in the range of 0.15−0.92 μm at zero contribution of Graphene oxide nanosheets.
References
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Journal ArticleDOI
Hydrogels for biomedical applications.
TL;DR: The composition and synthesis of hydrogels, the character of their absorbed water, and permeation of solutes within their swollen matrices are reviewed to identify the most important properties relevant to their biomedical applications.
Journal ArticleDOI
3D bioprinting of tissues and organs
Sean V. Murphy,Anthony Atala +1 more
TL;DR: 3D bioprinting is being applied to regenerative medicine to address the need for tissues and organs suitable for transplantation and developing high-throughput 3D-bioprinted tissue models for research, drug discovery and toxicology.
Journal ArticleDOI
Hydrogels for tissue engineering: scaffold design variables and applications.
Jeanie L. Drury,David J. Mooney +1 more
TL;DR: Hydrogels are an appealing scaffold material because they are structurally similar to the extracellular matrix of many tissues, can often be processed under relatively mild conditions, and may be delivered in a minimally invasive manner.
Journal ArticleDOI
Hydrogels in regenerative medicine
Brandon V. Slaughter,Shahana S. Khurshid,Omar Z. Fisher,Ali Khademhosseini,Nicholas A. Peppas +4 more
TL;DR: The properties of hydrogels that are important for tissue engineering applications and the inherent material design constraints and challenges are discussed.
Journal ArticleDOI
A 3D bioprinting system to produce human-scale tissue constructs with structural integrity
TL;DR: An integrated tissue–organ printer (ITOP) that can fabricate stable, human-scale tissue constructs of any shape is presented and the incorporation of microchannels into the tissue constructs facilitates diffusion of nutrients to printed cells, thereby overcoming the diffusion limit of 100–200 μm for cell survival in engineered tissues.