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Journal ArticleDOI

A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases.

01 Jul 1957-American Journal of Clinical Pathology (AMERICAN JOURNAL OF CLINICAL PATHOLOGY)-Vol. 28, Iss: 1, pp 56-63
About: This article is published in American Journal of Clinical Pathology.The article was published on 1957-07-01. It has received 9424 citations till now.
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Journal ArticleDOI
TL;DR: The methanol extract of Anacardium occidentale stem bark was evaluated for activities against the lipopolysaccharide (LPS)-induced septic shock, as well as LPS-induced microvascular permeability in mice, and produced marked reduction in elevated levels of transferases.

114 citations

Journal ArticleDOI
TL;DR: It is evoked that CBLE administration enhanced the performance, feed utilization, antioxidant, and innate immunity properties of African catfish with optimum level of 12g/kg diet, which is significantly enhanced by CBLE supplementation.

113 citations

01 Jan 2007
TL;DR: In this article, the n-hexane extract of Syzygium aromaticum was extracted using gas chromatography-mass spectroscopy (GC-MS) and the major components were eugenol (71.56 %) and Eugenol acetate (8.99 %), along with limonin and ferulic aldehyde.
Abstract: Sixteen volatile compounds were identified from the n-hexane extract of the buds of Syzygium aromaticum by using gas chromatography-mass spectroscopy (GC-MS). The major components were eugenol (71.56 %) and eugenol acetate (8.99 %). The dichloromethane extract of the buds yielded limonin and ferulic aldehyde, along with eugenol. The flavonoids tamarixetin 3- O-b-D-glucopyranoside, ombuin 3-O-b-D-glucopyranoside and quercetin were isolated from the ethanol extract; identifications of all these compounds were established by chemical and spectroscopic methods including 1D and 2D NMR. This is the first report of limonin, ferulic aldehyde and these flavonoids from this plant. All extracts and the isolated flavonoids showed strong antioxidant activity against 1, 2-diphenyl picrylhydrazyl (DPPH). Among the tested extracts, the ethanol extract of the clove buds showed remarkable scavenging activity, as compared with synthetic antioxidants such as butylated hydroxyl toluene (BHT). The ethanol extract of clove showed remarkable hepatoprotective activity against paracetamol-induced liver injury in female rats.

113 citations


Cites methods from "A colorimetric method for the deter..."

  • ...The activity of AST and ALT were measured according to the method described by Reitman and Frankel (1957)....

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Journal ArticleDOI
TL;DR: The hepatoprotective effects of bergenin, a major constituent of Mallotus japonicus, were evaluated against carbon tetrachloride (CCl 4 )-induced liver damage in rats.

113 citations

Journal ArticleDOI
TL;DR: Garlic or the mix including garlic appears to have an impact on each of the measures more effectively than ginger and turmeric and may have a role in alleviating the risks of the metabolic syndrome and cardiovascular complications.
Abstract: Spices which show hypoglycaemic, hypolipidaemic and antioxidant activities may have a role in the treatment of diabetes and its complications. The present study aimed to compare the modulatory effects of garlic, ginger, turmeric and their mixture on the metabolic syndrome and oxidative stress in streptozotocin (STZ)-nicotinamide diabetic rats. Diabetes was induced in overnight fasted rats by a single intraperitoneal injection of STZ (65 mg/kg body weight) and nicotinamide (110 mg/kg body weight, 15 min before STZ injection). Diabetic rats orally received either distilled water (as vehicle) or 200 mg/kg body weight of garlic bulb, ginger rhizome or turmeric rhizome powder suspension separately or mixed together (GGT mixture) for twenty-eight consecutive days. The results showed that these spices and their mixture significantly alleviated (80-97 %, P < 0·05-0·001) signs of the metabolic syndrome (hyperglycaemia and dyslipidaemia), the elevation in atherogenic indices and cellular toxicity in STZ-nicotinamide diabetic rats by increasing the production of insulin (26-37 %), enhancing the antioxidant defence system (31-52 %, especially GSH) and decreasing lipid peroxidation (60-97 %). The greatest modulation was seen in diabetic rats that received garlic and the GGT mixture (10-23 % more than that in the ginger and turmeric groups). In conclusion, garlic or the mix including garlic appears to have an impact on each of the measures more effectively than ginger and turmeric and may have a role in alleviating the risks of the metabolic syndrome and cardiovascular complications.

112 citations


Cites methods from "A colorimetric method for the deter..."

  • ...HDL-cholesterol ratio: Serum alanine aminotransferase (ALAT) and aspartate aminotransferase activities were colorimetrically measured((22))....

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