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Journal ArticleDOI

A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases.

01 Jul 1957-American Journal of Clinical Pathology (AMERICAN JOURNAL OF CLINICAL PATHOLOGY)-Vol. 28, Iss: 1, pp 56-63
About: This article is published in American Journal of Clinical Pathology.The article was published on 1957-07-01. It has received 9424 citations till now.
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TL;DR: The results showed that T. asiatica leaves ethyl acetate extract (TALEe) exerted significant antidiabetic and antioxidant effects in STZ-induced diabetic rats justifying its traditional use.

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Cites methods from "A colorimetric method for the deter..."

  • ...SGOT and SGPT activities were determined by the method of Reitman and Frankel (1957)....

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TL;DR: The results indicated B(a)P as the most genotoxic compound, followed by NAPH and BNF (B( a)P>NAPH>BNF).

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TL;DR: The results suggest that ZSP exerts an effective protection against CCl4-induced hepatic injury by mediating antioxidative and free radical scavenging activities.

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Journal ArticleDOI
TL;DR: The results show that FA is an effective antioxidant without any side‐effects and may be a great gain in the current search for natural therapy.
Abstract: The present work is aimed at evaluating the protective effect of ferulic acid (FA), a naturally occurring phenolic compound on CCl4 induced toxicity. The activities of liver markers (alanine transaminase, aspartate transaminase, alkaline phosphatase, gamma-glutamyl transferase), lipid peroxidative index (thiobarbituric acid-reactive substances, hydroperoxides, nitric oxide, protein carbonyl content), the antioxidant status (superoxide dismutase, catalase, glutathione peroxidase and reduced glutathione) were used as biomarkers to monitor the protective role of FA. The liver marker enzymes in plasma and lipid peroxidative index in liver and kidney were increased in CCl4-treated groups, which were decreased significantly on treatment with FA. The antioxidants, which were depleted in CCl4-treated groups, were improved significantly by FA treatment. Administration of FA to normal rats did not produce any harmful effects. Thus our results show that FA is an effective antioxidant without any side-effects and may be a great gain in the current search for natural therapy.

110 citations