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Journal ArticleDOI

A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases.

01 Jul 1957-American Journal of Clinical Pathology (AMERICAN JOURNAL OF CLINICAL PATHOLOGY)-Vol. 28, Iss: 1, pp 56-63
About: This article is published in American Journal of Clinical Pathology.The article was published on 1957-07-01. It has received 9424 citations till now.
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TL;DR: Results of this study show that C. berryi (Arn) Engl bark can be proposed to protect the liver against CCl(4)-induced oxidative damage in rats, and the hepatoprotective effect might be correlated with its antioxidant and free radical scavenger effects.

102 citations


Cites methods from "A colorimetric method for the deter..."

  • ...Hepatic enzymes, AST and ALT were used as the biochemical markers of the hepatic damage and were assayed by the method of Reitman and Frankel (1957)....

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Journal ArticleDOI
TL;DR: The results showed that the dietary OEO significantly improved the growth parameters (final body weight, weight gain, Weight gain %, specific growth rate, and feed intake) (P).

102 citations

Journal ArticleDOI
TL;DR: The hypothesis that both black and green teas may have beneficial effects against the risks of the metabolic syndrome and CVD as shown in rat models of human obesity and diabetes is supported.
Abstract: Cardiovascular complications are a major cause of morbidity and mortality in patients with diabetes, obesity and the metabolic syndrome. Recently, there has been an increasing interest in tea as a protective agent against CVD. Here, we compared the modulatory effects of two different doses (50 and 100 mg/kg body weight given orally for 28 consecutive days) of black tea aqueous extract (BTE, rich in theaflavins and thearubigins) and green tea aqueous extract (GTE, rich in catechins) on experimentally induced hyperglycaemia, hyperlipidaemia and liver dysfunction by alloxan (which destroys pancreatic beta-cells and induces type 1 diabetes) and a cholesterol-rich diet (which induces obesity and type 2 diabetes) in male Wistar albino rats. Both tea extracts significantly alleviated most signs of the metabolic syndrome including hyperglycaemia (resulting from type 1 and 2 diabetes), dyslipidaemia and impairment of liver functions induced by alloxan or the cholesterol-rich diet in the animals. Also, the tea extracts significantly modulated both the severe decrease and increase in body weight induced by alloxan and the high-cholesterol diet, respectively. The modulatory effects obtained here were partial or complete, but significant and dose dependent, and slightly more in GTE in most cases. No harmful effects were detected for tea consumption on all parameters measured, except that the high dose of both tea extracts significantly decreased the spleen weight:body weight ratio and induced lymphopenia. The present study supports the hypothesis that both black and green teas may have beneficial effects against the risks of the metabolic syndrome and CVD as shown in rat models of human obesity and diabetes.

102 citations


Cites methods from "A colorimetric method for the deter..."

  • ...Serum alanine and aspartate aminotransferases and alkaline phosphatase (ALP) activities were estimated either colorimetrically or kinetically using BioMérieux SA (Marcy-l’Etoile, France) and Biocon Diagnostik (Vöhl-Marienhagen, Germany) kits((32,33))....

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Journal ArticleDOI
TL;DR: A series of 1,3-benzothiazol-2-yl benzamides prepared in satisfactory yield and evaluated for their anticonvulsant, neurotoxicity, CNS depressant study and other toxicity studies showed the decrease in the immobility time.

102 citations

Journal ArticleDOI
TL;DR: Data indicate that liver reduced GSH concentration is important in modulating Cd-induced hepatotoxicity as evidenced by marked decreases in plasma ALT, AST, and SDH activities.

102 citations