scispace - formally typeset
Search or ask a question
Journal ArticleDOI

A Few Spanish Pearls for the American Journal of Gastroenterology.

07 Nov 2017-The American Journal of Gastroenterology (Nature Publishing Group)-Vol. 112, Iss: 12, pp 1759-1760
TL;DR: How “cost-zero” research in Spain combined with international competitive pressure created a strong collaboration of independent support networks through researcher associations and societies is described, and how this collaboration has become one of the most important contributors to Spanish Gastroenterology.
About: This article is published in The American Journal of Gastroenterology.The article was published on 2017-11-07 and is currently open access. It has received None citations till now.

Summary (1 min read)

Jump to:  and [INTERNATIONAL DATELINE]

INTERNATIONAL DATELINE

  • Including the EPICOLON (estudio de la EPIdemiologia del cáncer de COLON) I and II as well as COLONPREV (COLON PREVention study), which have already resulted in important reports.
  • Th e COLONPREV project ( 6 ) will be the fi rst RCT to provide 10-year mortality data, comparing colonoscopy and biennial FIT, as screening methods for intermediate risk populations over the age of 50.
  • Th e EST-CPRE study, a retrospective analysis of consecutive patients undergoing Endoscopic Retrograde Cholangiopancreatography (ERCP) in four centers in Spain, found that patients consuming statins had a 70% lower risk of post-ERCP acute pancreatitis.
  • Crucially, these studies have advanced the understanding that GERD and EoE are not mutually exclusive disorders, and that there is a clear EoE phenotype with complete remission on PPIs, with or without GERD.

Did you find this useful? Give us your feedback

References
More filters
Journal ArticleDOI
TL;DR: Research electronic data capture (REDCap) is a novel workflow methodology and software solution designed for rapid development and deployment of electronic data Capture tools to support clinical and translational research.

29,988 citations

Journal ArticleDOI
TL;DR: Subjects in the FIT group were more likely to participate in screening than were those in the colonoscopy group, and more adenomas were identified in thecolorectal cancer group.
Abstract: The rate of participation was higher in the FIT group than in the colonoscopy group (34.2% vs. 24.6%, P<0.001). Colorectal cancer was found in 30 subjects (0.1%) in the colonoscopy group and 33 subjects (0.1%) in the FIT group (odds ratio, 0.99; 95% confidence interval [CI], 0.61 to 1.64; P = 0.99). Advanced adenomas were detected in 514 subjects (1.9%) in the colonoscopy group and 231 subjects (0.9%) in the FIT group (odds ratio, 2.30; 95% CI, 1.97 to 2.69; P<0.001), and nonadvanced adenomas were detected in 1109 subjects (4.2%) in the colonoscopy group and 119 subjects (0.4%) in the FIT group (odds ratio, 9.80; 95% CI, 8.10 to 11.85; P<0.001). Conclusions Subjects in the FIT group were more likely to participate in screening than were those in the colonoscopy group. On the baseline screening examination, the numbers of subjects in whom colorectal cancer was detected were similar in the two study groups, but more adenomas were identified in the colonoscopy group. (Funded by Instituto de Salud Carlos III and others; ClinicalTrials.gov number, NCT00906997.)

692 citations

Journal ArticleDOI
TL;DR: Evidence-based recommendations for EoE diagnosis, treatment modalities, and patients’ follow up are proposed in the guidelines, and expert opinion and best clinical practice are provided.
Abstract: IntroductionEosinophilic esophagitis (EoE) is one of the most prevalent esophageal diseases and the leading cause of dysphagia and food impaction in children and young adults. This underlines the importance of optimizing diagnosys and treatment of the condition, especially after the increasing amount of knowledge on EoE recently published. Therefore, the UEG, EAACI ESPGHAN, and EUREOS deemed it necessary to update the current guidelines regarding conceptual and epidemiological aspects, diagnosis, and treatment of EoE.MethodsGeneral methodology according to the Appraisal of Guidelines for Research and Evaluation (AGREE) II and the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system was used in order to comply with current standards of evidence assessment in formulation of recommendations. An extensive literature search was conducted up to August 2015 and periodically updated. The working group consisted of gastroenterologists, allergists, pediatricians, otolaryngologists, path...

665 citations

Journal ArticleDOI
TL;DR: Antisecretory agent or nitrate treatment is associated with reduced UGIB RR in patients taking NSAID or aspirin, and protection was not apparent in patientsTaking anticoagulants.

298 citations

Journal ArticleDOI
TL;DR: Peptic ulcer rebleeding virtually does not occur in patients with complicated ulcers after H. pylori eradication, and maintenance anti-ulcer (antisecretory) therapy is not necessary if eradication is achieved.

72 citations