A global reference for human genetic variation.
Citations
518 citations
Cites background from "A global reference for human geneti..."
...Recently, large reference datasets, such as those from the 1000 Genomes Project Consortium (1), Exome Sequencing Project (ESP) (2) and Exome Aggregation Consortium (ExAC) (3), have become publicly available for the benefit of the biomedical community....
[...]
509 citations
502 citations
499 citations
Cites background from "A global reference for human geneti..."
...Genomic surveys of individuals from multiple populations have revealed significant genetic heterogeneity, with over 80 million autosomal single nucleotide polymorphisms (SNPs), including 8million common variants (Auton et al., 2015)....
[...]
495 citations
Cites methods from "A global reference for human geneti..."
...Common variants were imputed using IMPUTE2 (Howie et al., 2009, 2011) using 1000 Genomes Phase 3 reference genotypes (1000 Genomes Project Consortium et al., 2015)....
[...]
References
88,255 citations
45,957 citations
18,858 citations
13,548 citations
10,164 citations