A History of Calcium Orthophosphates (CaPO 4 ) from 1770s till 1950
01 Jan 2014-
TL;DR: A detailed annals of the knowledge development on CaPO 4 can be found in this article, where the authors provide a detailed overview of the past knowledge development of CaPO4.
Abstract: Due to the chemical similarity with human bones and teeth, calcium orthophosphates (CaPO 4 ) are the inorganic substances of a special importance for the human being: they appear to be the excellent compounds to construct artificial bone grafts. In addition, CaPO 4 are necessary for both animals and plants as the source of important chemical elements. Obviously, these well known facts have not become apparent immediately; thus, the purpose of this article is to provide the detailed annals of the knowledge development on CaPO 4 . The chosen time scale started with the earliest available studies of shortly before 1770s (to the best of my findings, CaPO 4 had been unknown before), passed through the entire nineteenth century and finished in 1950, because since then the amount of publications rapidly increased and the subject became too broad. In addition, since publications of the second half of the twentieth century are easily accessible, other scientists have already reviewed the substantial amount of them. Many forgotten and poorly known historical facts, names, approaches, concepts, and misconceptions have been extracted from the old publications. To maximize objectivity, an extensive quotation has been used. Then the old data have been systematized, reanalyzed, and reconsidered from the modern points of view. The reported historical findings clearly demonstrate that many famous scientists of the past contributed to the subject. Furthermore, the significant quantity of the modern scientific facts, ideas, and experimental approaches appear to have been known for very many decades and, in fact, a good deal of the recent investigations on CaPO 4 is just either a further development of the earlier studies or a rediscovery of the already forgotten knowledge.
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