A kinetic model of the central carbon metabolism for acrylic acid production in Escherichia coli
read more
Citations
Prospects for carbon-negative biomanufacturing.
Heterologous Production of Acrylic Acid: Current Challenges and Perspectives
Omics data for sampling thermodynamically feasible kinetic models.
Metabolic engineering to improve production of 3-hydroxypropionic acid from corn-stover hydrolysate in Aspergillus species
References
Purification and Properties of Glycerol Kinase from Escherichia coli
Purification and properties of L-Aspartate-alpha-decarboxylase, an enzyme that catalyzes the formation of beta-alanine in Escherichia coli.
Propionyl-coenzyme A synthase from Chloroflexus aurantiacus, a key enzyme of the 3-hydroxypropionate cycle for autotrophic CO2 fixation.
Glutamate dehydrogenase from Escherichia coli: purification and properties.
Escherichia coli l-aspartate-alpha -decarboxylase : preprotein processing and observation of reaction intermediates by electrospray mass spectrometry
Related Papers (5)
Two-dimensional isobutyl acetate production pathways to improve carbon yield
Frequently Asked Questions (11)
Q2. How many yields are achieved from microbial feedstocks?
to minimise production cust, the pathway should consist in 37 the direct bio-based production from microbial feedstocks, such as Escherichia coli, but the current 38 yields achieved are still to low to compete with conventional method.
Q3. What is the name of the chemical compound that is important to the world?
433Introduction 44Acrylic acid (AA) (C3H4O2) is an important chemical compound that is one of the key 45 components of superabsorbent polymers [1–3].
Q4. How much is the market for acrylic acid?
According to the Allied Market Research, in 2015, the 46 global market for AA was valued at 12,500 million US dollars, and is expected to reach 19,500 million 47 US dollars until 2022 [4].
Q5. What is the main reason why acrylic acid is an economically important chemical compound?
33 Nevertheless, the majority of acrylic acid consumed worldwide its produced from petroleum 34 derivatives by a purely chemical process, which is not only expensive, but it also contributes towards 35 environment deterioration.
Q6. What is the main reason why AA is produced?
Despite its economic importance, the vast majority of AA is still produced 48 by the oxidation of propylene or propane in a purely chemical process [1,5,6].
Q7. How is the synthesis of 3-64 HP identified?
the synthesis of 3-64 HP is well reported, and three distinct pathways have been identified, namely the glycerol route, the 65 malonyl-CoA route, and the β-alanine route.
Q8. What is the main reason why the AA industry is attracting the attention of the scientific community?
the development of an innovative and sustainable biological 51 production method has been attracting the attention of the scientific community [1,2,7].
Q9. How can a more sustainable bioprocess be used?
in recent years, it has been proven that it is possible to use engineered Escherichia 60 coli to convert glucose or glycerol into AA.
Q10. What is the main reason for the low yields of AA?
Despite the substantial improvements obtained with these methods, this process involves a 55 catalytic step that increases the production costs and environmental impact due to high energy demands 56 [1–3,5].
Q11. What is the main part of the bioprocess?
Like in the semi-biological methods, the bioprocess is also 61 divided into two main parts, the production of 3-HP and its subsequent conversion to AA.