A late arterial complication related to veno-arterial extracorporeal membrane oxygenation in a child.
About: This article is published in JMV-Journal de Médecine Vasculaire.The article was published on 2021-06-25. It has received None citations till now. The article focuses on the topics: Extracorporeal membrane oxygenation.
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Francesco Lo-Coco1, Giuseppe Avvisati, Marco Vignetti, Christian Thiede2, Simona Iacobelli1, Felicetto Ferrara, Paola Fazi, Laura Cicconi1, E. Di Bona, Giorgina Specchia3, Simona Sica4, Mariadomenica Divona1, Alessandro Levis, Walter Fiedler5, Elisa Cerqui, Massimo Breccia6, Giuseppe Fioritoni, Mario Cazzola, L. Melillo7, Enrica Morra, Bernd Hertenstein, Mohammed Wattad, Michael Lübbert8, Mathias Hänel, Norbert Schmitz, Alessandro Rambaldi, G. La Nasa9, Mario Luppi10, Fabio Ciceri11, Olimpia Finizio, Adriano Venditti1, Francesco Fabbiano, Konstanze Döhner12, M. Sauer2, Arnold Ganser13, Sergio Amadori1, Franco Mandelli, Hartmut Döhner12, Gerhard Ehninger2 •
University of Rome Tor Vergata1, Dresden University of Technology2, University of Bari3, Catholic University of the Sacred Heart4, University of Hamburg5, Sapienza University of Rome6, Casa Sollievo della Sofferenza7, University of Freiburg8, University of Cagliari9, University of Modena and Reggio Emilia10, Vita-Salute San Raffaele University11, University of Ulm12, Hannover Medical School13
TL;DR: ATRA plus arsenic trioxide is at least not inferior and may be superior to ATRA plus chemotherapy in the treatment of patients with low-to-intermediate-risk APL.
Abstract: Background All-trans retinoic acid (ATRA) with chemotherapy is the standard of care for acute promyelocytic leukemia (APL), resulting in cure rates exceeding 80%. Pilot studies of treatment with arsenic trioxide with or without ATRA have shown high efficacy and reduced hematologic toxicity. Methods
1,184 citations
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TL;DR: Although ECMO can improve survival of patients with advanced heart disease, there is significant associated morbidity with performance of this intervention.
651 citations
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Alan L. Davis, Joseph A. Carcillo1, Rajesh K. Aneja1, Andreas J. Deymann2, John C. Lin3, Trung C. Nguyen4, Regina Okhuysen-Cawley4, Monica S. Relvas5, Ranna A. Rozenfeld6, Peter Skippen7, Bonnie J. Stojadinovic8, Eric A. Williams4, Tim S. Yeh9, Fran Balamuth10, Joe Brierley11, Allan R. de Caen12, Ira M. Cheifetz13, Karen Choong14, Edward E. Conway15, Timothy T. Cornell16, Allan Doctor3, Marc Andre Dugas17, Jonathan D. Feldman18, Julie C. Fitzgerald10, Heidi R. Flori16, James D. Fortenberry19, Ana Lia Graciano20, Bruce M. Greenwald21, Mark W. Hall22, Yong Yun Han23, Lynn J. Hernan24, Jose Irazuzta25, Elizabeth Iselin26, Elise W. van der Jagt27, Howard E. Jeffries28, Saraswati Kache29, Chhavi Katyal15, Niranjan Kissoon7, Alexander A. Kon30, Martha C. Kutko31, Graeme MacLaren32, Graeme MacLaren33, Timothy M. Maul1, Renuka Mehta, Fola Odetola16, Kristine A Parbuoni34, Raina Paul6, Mark J. Peters35, Suchitra Ranjit36, Karin Reuter-Rice13, Eduardo Schnitzler37, Halden F. Scott38, Adalberto Torres39, Jacki Weingarten-Abrams15, Scott L. Weiss20, Jerry J. Zimmerman28, Aaron L. Zuckerberg20 •
University of Pittsburgh1, Riley Hospital for Children2, Washington University in St. Louis3, Baylor College of Medicine4, Texas Tech University5, Northwestern University6, University of British Columbia7, Medical College of Wisconsin8, Saint Barnabas Medical Center9, University of Pennsylvania10, University College London11, University of Alberta12, Duke University13, McMaster University14, Yeshiva University15, University of Michigan16, Laval University17, Kaiser Permanente18, Emory University19, University of Maryland, Baltimore20, Cornell University21, Nationwide Children's Hospital22, Children's Mercy Hospital23, Texas Tech University Health Sciences Center at El Paso24, University of Florida25, St Mary's Hospital26, University of Rochester27, University of Washington28, Stanford University29, University of California, San Diego30, Valley Hospital31, Royal Children's Hospital32, University of Melbourne33, Loma Linda University34, Great Ormond Street Hospital35, Boston Children's Hospital36, Austral University37, University of Colorado Denver38, Nemours Foundation39
TL;DR: A major new recommendation in the 2014 update of the 2007 American College of Critical Care Medicine “Clinical Guidelines for Hemodynamic Support of Neonates and Children with Septic Shock” is consideration of institution—specific use of a recognition bundle containing a trigger tool for rapid identification of patients with septic shock.
Abstract: Objectives:The American College of Critical Care Medicine provided 2002 and 2007 guidelines for hemodynamic support of newborn and pediatric septic shock Provide the 2014 update of the 2007 American College of Critical Care Medicine “Clinical Guidelines for Hemodynamic Support of Neonates and Child
605 citations
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TL;DR: New insights into the pathogenesis of DIC and MODS may have implications for the development of new therapeutic agents potentially useful for the management of severe sepsis.
283 citations
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Heidi J. Dalton1, Ron W Reeder2, Pamela Garcia-Filion1, Richard Holubkov2, Robert A. Berg3, Athena F. Zuppa3, Frank W. Moler4, Thomas P. Shanley4, Murray M. Pollack1, Christopher J. L. Newth5, John T. Berger6, David L. Wessel6, Joseph A. Carcillo7, Michael J. Bell7, Sabrina M. Heidemann1, Kathleen L. Meert1, Rick Harrison8, Allan Doctor9, Robert F. Tamburro10, J. Michael Dean2, Tammara L. Jenkins10, Carol Nicholson10 •
Boston Children's Hospital1, University of Utah2, University of Pennsylvania3, University of Michigan4, University of Southern California5, Children's National Medical Center6, University of Pittsburgh7, University of California, Los Angeles8, Washington University in St. Louis9, National Institutes of Health10
TL;DR: In this article, a prospective, observational cohort study in pediatric, cardiac, and neonatal intensive care units in eight hospitals, carried out from December 2012 to September 2014, was carried out to measure the incidence of bleeding (blood loss requiring transfusion or intracranial hemorrhage) and thrombosis during ECMO support.
Abstract: Rationale: Extracorporeal membrane oxygenation (ECMO) is used for respiratory and cardiac failure in children but is complicated by bleeding and thrombosis.Objectives: (1) To measure the incidence of bleeding (blood loss requiring transfusion or intracranial hemorrhage) and thrombosis during ECMO support; (2) to identify factors associated with these complications; and (3) to determine the impact of these complications on patient outcome.Methods: This was a prospective, observational cohort study in pediatric, cardiac, and neonatal intensive care units in eight hospitals, carried out from December 2012 to September 2014.Measurements and Main Results: ECMO was used on 514 consecutive patients under age 19 years. Demographics, anticoagulation practices, severity of illness, circuitry components, bleeding, thrombotic events, and outcome were recorded. Survival was 54.9%. Bleeding occurred in 70.2%, including intracranial hemorrhage in 16%, and was independently associated with higher daily risk of mortality....
230 citations