Fig 1. Variance explained over allele frequency. The cumulative additive and dominance genetic variance which can be explained by markers whose frequencies, q, are x. Each color represents a different value of λ: the mean effects size of a new deleterious mutation. Shown here are the gene-based (GBR), additive co-dominant (AC), incomplete multiplicative recessive (Mult. recessive (h = 0.25); iMR) and complete multiplicative recessive (Mult. recessive (h = 0);cMR) models. Solid lines show the additive variance alone and dotted lines show the combined additive and dominance variance. All data shown are for models where H2 * 0.08. These particular results are robust to changes H2 when VG is not changed, as is the case here. The additive and dominance genetic variance is estimated by the adjusted r2 of the regression of all markers (and their corresponding dominance encoding) with q x onto total genotypic value (see methods for details); data are displayed as the mean of 250 simulation replicates. The vertical dotted and dashed lines correspond to the q = 0.001 and q = 0.05, respectively. The curves under no growth appear to be truncated with respect to rapid growth because the range of the x-axis differs between growth and no growth (minimum q = 1/2N).
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