A new biphasic osteoinductive calcium composite material with a negative Zeta potential for bone augmentation.
Ralf Smeets,Andreas Kolk,Marcus Gerressen,Oliver Driemel,Oliver Maciejewski,Benita Hermanns-Sachweh,Dieter Riediger,Jamal M. Stein +7 more
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TLDR
The BCC material was used in a bilateral sinus floor augmentation procedure and demonstrated a negative surface charge (negative Zeta potential) which was found to be favorable for bone regeneration and osseointegration of dental implants.Abstract:
The aim of the present study was to analyze the osteogenic potential of a biphasic calcium composite material (BCC) with a negative surface charge for maxillary sinus floor augmentation. In a 61 year old patient, the BCC material was used in a bilateral sinus floor augmentation procedure. Six months postoperative, a bone sample was taken from the augmented regions before two titanium implants were inserted at each side. We analyzed bone neoformation by histology, bone density by computed tomography, and measured the activity of voltage-activated calcium currents of osteoblasts and surface charge effects. Control orthopantomograms were carried out five months after implant insertion. The BCC was biocompatible and replaced by new mineralized bone after being resorbed completely. The material demonstrated a negative surface charge (negative Zeta potential) which was found to be favorable for bone regeneration and osseointegration of dental implants.read more
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Titanium nanostructures for biomedical applications
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Current trends and future perspectives of bone substitute materials - from space holders to innovative biomaterials.
Andreas Kolk,Jörg Handschel,Wolf Drescher,Daniel Rothamel,Frank Kloss,Marco Blessmann,Max Heiland,Klaus-Dietrich Wolff,Ralf Smeets +8 more
TL;DR: An overview of the principles of bone replacement, the types of graft materials available, and future perspectives are presented and a change from a simple replacement material to an individually created composite biomaterial with osteoinductive properties to enable enhanced defect bridging is proposed.
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Adhesion of osteoblasts to a nanorough titanium implant surface
Ekaterina Gongadze,Doron Kabaso,Sebastian Bauer,Tomaž Slivnik,Patrik Schmuki,Ursula van Rienen,Aleš Iglič +6 more
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Bioactive glass nanoparticles with negative zeta potential
Ali Doostmohammadi,Ali Doostmohammadi,Ahmad Monshi,Rasoul Salehi,Mohammadhossein Fathi,Zahra Golniya,Alma U. Daniels +6 more
TL;DR: In this article, the authors used the sol-gel method to produce and characterize SiO 2 -CaO-P 2 O 5 bioactive glass nanoparticles with negative zeta potential for possible use in biomedical applications.
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Dynamic Light Scattering Based Microelectrophoresis: Main Prospects and Limitations
TL;DR: It is argued that although zeta potential has been used as one of the main parameters in controlling the stability of colloidal dispersions, its application potentials are much broader and coupling the DLS-based microelectrophoretic systems with complementary characterization methods is mentioned asone of the prosperous paths for increasing the information output of these two analytical techniques.
References
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Osteoinduction, osteoconduction and osseointegration.
TL;DR: Osseointegration is the stable anchorage of an implant achieved by direct bone-to-implant contact in craniofacial implantology and this mode of anchorage is the only one for which high success rates have been reported.
Journal Article
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Journal Article
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TL;DR: The root and sinus series of the Omnii system have been used extensively and their design attempts to maximize the use of the available bone, and placement techniques allow the manipulation of bone to form sockets in otherwise deficient areas of bone.
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Porous hydroxyapatite and tricalcium phosphate cylinders with two different pore size ranges implanted in the cancellous bone of rabbits: a comparative histomorphometric and histologic study of bony ingrowth and implant substitution
P S Eggli,W Müller,R K Schenk +2 more
TL;DR: To investigate the histophysiology of implant degradation, hydroxyapatite and tricalcium phosphate cylinders with a diameter of 3 mm were implanted in the cancellous bone of the distal femur and the proximal tibia of 15 New Zealand White rabbits for up to six months and acid phosphatase-positive osteoclast-like cells suggesting active resorption adhere directly to the surface.