A Real-Time QRS Detection Algorithm
01 Mar 1985-IEEE Transactions on Biomedical Engineering (IEEE Trans Biomed Eng)-Vol. 32, Iss: 3, pp 230-236
TL;DR: A real-time algorithm that reliably recognizes QRS complexes based upon digital analyses of slope, amplitude, and width of ECG signals and automatically adjusts thresholds and parameters periodically to adapt to such ECG changes as QRS morphology and heart rate.
Abstract: We have developed a real-time algorithm for detection of the QRS complexes of ECG signals. It reliably recognizes QRS complexes based upon digital analyses of slope, amplitude, and width. A special digital bandpass filter reduces false detections caused by the various types of interference present in ECG signals. This filtering permits use of low thresholds, thereby increasing detection sensitivity. The algorithm automatically adjusts thresholds and parameters periodically to adapt to such ECG changes as QRS morphology and heart rate. For the standard 24 h MIT/BIH arrhythmia database, this algorithm correctly detects 99.3 percent of the QRS complexes.
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Patent•
21 May 1992TL;DR: In this paper, a method and apparatus for diagnosing heart rejection is disclosed. Heart rejection is diagnosed based on the pattern of interbeat intervals of the heart, which are measured shortly after transplant to establish a baseline pattern and compared to the baseline to detect changes from the baseline indicating rejection.
Abstract: A method and apparatus for diagnosing heart rejection is disclosed. Heart rejection is diagnosed based on the pattern of interbeat intervals. The interbeat intervals of the heart are measured shortly after transplant to establish a baseline pattern. The patterns of interbeat intervals from subsequent measurements are compared to the baseline to detect changes from the baseline indicating rejection. The apparatus of the invention measures the interbeat intervals using a Schmidt trigger that detects the upstroke of the QRS and produces a corresponding pulse. The intervals between pulses are timed to produce a series of interbeat interval measurements that are stored and analyzed. Software provides for automated pattern analysis.
40 citations
TL;DR: The current state-of-the-art of this technology is reviewed, the pros and cons of the devices and algorithms found in the literature and the possible research directions to develop the next generation of ambulatory monitoring systems are discussed.
Abstract: Cardiovascular diseases (CVDs) are the number one cause of death globally. An estimated 17.9 million people die from CVDs each year, representing 31% of all global deaths. Most cardiac patients require early detection and treatment. Therefore, many products to monitor patient's heart conditions have been introduced on the market. Most of these devices can record a patient's bio-metric signals both in resting and in exercising situations. However, reading the massive amount of raw electrocardiogram (ECG) signals from the sensors is very time-consuming. Automatic anomaly detection for the ECG signals could act as an assistant for doctors to diagnose a cardiac condition. This paper reviews the current state-of-the-art of this technology discusses the pros and cons of the devices and algorithms found in the literature and the possible research directions to develop the next generation of ambulatory monitoring systems.
40 citations
Cites methods from "A Real-Time QRS Detection Algorithm..."
...In the paper, they first used the Pan–Tompkins [56] algorithm to detect the R peaks on the ECG recordings....
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...Pan–Tompkins [56] 1985 116,137 115,860 507 277 99....
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...Inspired by the Pan–Tompkins algorithm, many researchers, such as [57–60] developed their own filter banks to improve the accuracy of the detection....
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...The Pan–Tompkins algorithm [56] is one of the most popular and earliest algorithms that has been implemented (Figure 14)....
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TL;DR: This work proposes an online ECG monitoring solution where normal heartbeats of each specific user are modeled by dictionaries yielding sparse representations, andheartbeats that do not conform to this model are detected as anomalous, thus enabling online and long-term monitoring.
40 citations
22 Oct 2007
TL;DR: A new system that can detect the heart beats of subjects during sleep by using bed installed load-cell sensors and shows the LF/HF ratio of the heart rate, one of the reflection parameters of ANS, acquired from the system for each sleep stage.
Abstract: Polysomnography is the standard method to score the sleep stages or to determine the quality of sleep. During all night examination, subjects must attach complicate and numerous electrodes on their body to acquire the biosignals. They can influence participants' sleep stage transition or sleep pattern, and the method seems intricate. In many researches, it is reported that autonomic nervous system (ANS) is varying with sleep stage transition and heart rate variability (HRV) is one of the indices which reflects the changes of autonomic nervous system. In this point of view, we can estimate the sleep quality by observing the HRV variation. In this study, to analyze the heart rate variability, we introduce a new system that can detect the heart beats of subjects during sleep by using bed installed load-cell sensors. The pressure to the sensor changes with the pulsation of the heart and we consider it as ballistocardiogram, the physical heart beat signal. To validate our system, we adopted this system for the 4 subjects with the polysomnography. The results show the LF/HF ratio of the heart rate, one of the reflection parameters of ANS, acquired from the system for each sleep stage. To validate the results, the HRV from electrocardiogram using Ag-AgCl electrodes will be compared.
40 citations
Cites methods from "A Real-Time QRS Detection Algorithm..."
...The Pan & Thompkins’ algorithm [9] for the ECG R peaks and our algorithm mentioned above for the BCG J peak were adopted to this data....
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TL;DR: The predictive utility of pretreatment heart rate variability (HRV) for outcomes of antidepressant medication in MDD is investigated, with pretreatment anxious depression as a hypothesized moderator of HRV effects.
Abstract: Background There is a need to identify biomarkers of treatment outcomes for major depressive disorder (MDD) that can be disseminated. We investigated the predictive utility of pretreatment heart rate variability (HRV) for outcomes of antidepressant medication in MDD, with pretreatment anxious depression as a hypothesized moderator of HRV effects. Methods A large, randomized, multicenter practical trial (International Study to Predict Optimized Treatment in Depression) in patients with current nonpsychotic MDD (N = 1,008; 722 completers) had three arms: escitalopram, sertraline, and venlafaxine-extended release. At pretreatment, patients were defined as having anxious (N = 309) versus nonanxious (N = 413) depression and their resting high-frequency HRV (root mean square of successive differences) was assessed. Patients' usual treating clinicians managed medication. At 8 weeks, primary outcomes were clinician-rated depressive symptom response and remission; secondary outcomes were self-reported response and remission. Results Pretreatment HRV predicted antidepressant outcomes as a function of anxious versus nonanxious depression. In anxious depression, patients with higher HRV had better outcomes, whereas patients with lower HRV had poorer outcomes. In nonanxious depression, patients with lower HRV had better outcomes, whereas patients with higher HRV had poorer outcomes. Some simple effects were not significant. Results did not differ by treatment arm and remained significant when controlling for important covariates. Conclusions These findings inform a precision medicine approach in which clinical and biological assessments may be integrated to facilitate treatment outcome prediction. Knowing about HRV may help determine which patients with anxious depression could benefit from antidepressants and which patients may require a different treatment approach.
39 citations
Cites methods from "A Real-Time QRS Detection Algorithm..."
...The ECG tachogram data were generated using a modified Tompkins algorithm (Pan & Tompkins, 1985) and rectified using a semi-automated method, in which the cardiac Rwave thresholds for checking, cleaning, deleting, andmarking for manual checking were previously established as optimal in the BRAINnet…...
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References
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TL;DR: This review asserts that most one-channel QRS detectors described in the literature can be considered as having the same basic structure and a discussion of some of the current detection schemes is presented.
Abstract: The QRS detection algorithm is an essential part of any computer-based system for the analysis of ambulatory ECG recordings. This review asserts that most one-channel QRS detectors described in the literature can be considered as having the same basic structure. A discussion of some of the current detection schemes is presented with regard to this structure. Some additional features of QRS detectors are mentioned. The evaluation of performance and the problem of multichannel detection, which is now gaining importance, are also briefly treated.
254 citations
TL;DR: The problem of detecting the QRS complex in the presence of noise was analysed and an optimised threshold criterion based on FP/FN was developed.
Abstract: The problem of detecting the QRS complex in the presence of noise was analysed. Most QRS detectors contain a filter to improve the signal-to-noise ratio and compare the signal with a threshold. In an earlier paper we identified an optimal filter. Various techniques to generate threshold and detector designs were studied. Automatic gain-control circuits with a fixed threshold have a very slow response to different rhythms. Automatic threshold circuits based on simple peak-detection schemes have a fast response, but are very sensitive to sudden variations in QRS amplitudes and noise transients. None of the methods described to date present any optimisation criteria for detecting the signal (QRS complex) in the presence of noise. The probabilities of FPs (false positives) and FNs (false negatives) were investigated and an optimised threshold criterion based on FP/FN was developed. Presently, data are being collected to compare various techniques from their ROC (receiver operating characteristics).
151 citations
TL;DR: An automated Holtes scanning system based on two microcomputers that detects QRS complexes and measures the QRS durations using computations of first and second derivatives, and can process Holter tapes at 60 times real time and produce printed summaries and 24 h trend plots.
Abstract: We have developed an automated Holtes scanning system based on two microcomputers. One is a preprocessor that detects QRS complexes and measures the QRS durations using computations of first and second derivatives. Thismicrocomputer interfaces to a secondmicro-computer that does arrhythmia analysis, logging, and reporting using R-R intervals and QRS durations. This system can process Holter tapes at 60 times real time and produce printed summaries and 24 h trend plots of several variables including heart rate and PVC count.
127 citations
"A Real-Time QRS Detection Algorithm..." refers methods in this paper
...The slope of the R wave is a popular signal feature used to locate the QRS complex in many QRS detectors [5]....
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TL;DR: The possibilities for extending the class of lowpass recursive digital filters to include high pass, bandpass, and bandstop filters are described, and experience with a PDP 11 computer has shown that these filters may be programmed simply using machine code, and that online operation at sampling rates up to about 8 kHz is possible.
Abstract: After reviewing the design of a class of lowpass recursive digital filters having integer multiplier and linear phase characteristics, the possibilities for extending the class to include high pass, bandpass, and bandstop (‘notch’) filters are described. Experience with a PDP 11 computer has shown that these filters may be programmed simply using machine code, and that online operation at sampling rates up to about 8 kHz is possible. The practical application of such filters is illustrated by using a notch desgin to remove mains-frequency interference from an e.c.g. waveform.
104 citations
TL;DR: In this paper a new robust single lead QRS-detection algorithm is presented, allowing real-time applications and results are presented.
101 citations