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Journal ArticleDOI

A Real-Time QRS Detection Algorithm

01 Mar 1985-IEEE Transactions on Biomedical Engineering (IEEE Trans Biomed Eng)-Vol. 32, Iss: 3, pp 230-236
TL;DR: A real-time algorithm that reliably recognizes QRS complexes based upon digital analyses of slope, amplitude, and width of ECG signals and automatically adjusts thresholds and parameters periodically to adapt to such ECG changes as QRS morphology and heart rate.
Abstract: We have developed a real-time algorithm for detection of the QRS complexes of ECG signals. It reliably recognizes QRS complexes based upon digital analyses of slope, amplitude, and width. A special digital bandpass filter reduces false detections caused by the various types of interference present in ECG signals. This filtering permits use of low thresholds, thereby increasing detection sensitivity. The algorithm automatically adjusts thresholds and parameters periodically to adapt to such ECG changes as QRS morphology and heart rate. For the standard 24 h MIT/BIH arrhythmia database, this algorithm correctly detects 99.3 percent of the QRS complexes.

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Citations
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Patent
24 Jul 2003
TL;DR: In this article, a method and apparatus for electro-biometric identity recognition or verification was proposed, producing and storing a first biometric signature that identifies a specific individual by forming the difference between a representation of the heartbeat pattern of the specific individual and a stored representation of common features of the heartbeats of a plurality of individuals.
Abstract: A method and apparatus for electro-biometric identity recognition or verification, producing and storing a first biometric signature that identifies a specific individual by forming the difference between a representation of the heartbeat pattern of the specific individual and a stored representation of common features of the heartbeat patterns of a plurality of individuals; after the producing step, obtaining a representation of the heartbeat pattern of a selected individual and producing a second biometric signature by forming the difference between the heartbeat pattern of the selected individual and the stored representation of common features of the heartbeat patterns of the plurality of individuals; and comparing the second biometric signature with the first biometric signature to determine whether the selected individual is the specific individual.

223 citations

Journal ArticleDOI
TL;DR: In this paper, a novel electrocardiogram (ECG) classification algorithm is proposed for continuous cardiac monitoring on wearable devices with limited processing capacity, which employs a novel architecture consisting of wavelet transform and multiple long short-term memory (LSTM) recurrent neural networks.
Abstract: Objective : A novel electrocardiogram (ECG) classification algorithm is proposed for continuous cardiac monitoring on wearable devices with limited processing capacity. Methods : The proposed solution employs a novel architecture consisting of wavelet transform and multiple long short-term memory (LSTM) recurrent neural networks (see Fig. 1 ). Results : Experimental evaluations show superior ECG classification performance compared to previous works. Measurements on different hardware platforms show the proposed algorithm meets timing requirements for continuous and real-time execution on wearable devices. Conclusion : In contrast to many compute-intensive deep-learning based approaches, the proposed algorithm is lightweight, and therefore, brings continuous monitoring with accurate LSTM-based ECG classification to wearable devices. Significance : The proposed algorithm is both accurate and lightweight. The source code is available online at http://lis.ee.sharif.edu .

223 citations

Journal ArticleDOI
TL;DR: Infusion of endotoxin into human volunteers causes loss of heart rate variability, as measured by standard deviation and power spectra, as well as an increase in heart rate regularity, as Measure of regularity occurred earlier than changes in otherheart rate variability measures and may be a useful means of detecting early sepsis.
Abstract: Objective To determine whether human endotoxemia is associated with a loss of the physiologic beat-to-beat variability of heart rate. Design Prospective, randomized, crossover, single-blind study. Setting Clinical research center in a federal, nonuniversity hospital. Subjects Healthy volunteers. Interventions Intravenous administration of reference (Escherichia coli) endotoxin or saline placebo, with or without previous administration of oral ibuprofen. Measurements and main results Electrocardiograms were continuously recorded and digitized using series of 1000 beat epochs of R-R intervals over 8 hrs. Analyses included measures in the time domain (standard deviation), frequency domain (power spectra), and a measure of regularity (approximate entropy). Endotoxin administration was associated with loss of variability by all measures. This loss of variability remained significant even with administration of ibuprofen, which blocked the development of fever and endotoxin-related symptoms. Conclusions Infusion of endotoxin into human volunteers causes loss of heart rate variability, as measured by standard deviation and power spectra, as well as an increase in heart rate regularity, as measured by approximate entropy. Changes in approximate entropy occurred earlier than changes in other heart rate variability measures and may be a useful means of detecting early sepsis. This reduction in regularity is consistent with a model in which the pathogenesis of multiple organ system dysfunction syndrome involves the physiologic uncoupling of vital organ systems.

222 citations

Journal ArticleDOI
Mirja Peltola1
TL;DR: This paper reviews the methods used for editing of the R–R interval time series and how this editing can influence the results of heart rate (HR) variability analyses, and summarizes the pre-processing methods for HR variability signal.
Abstract: Measurement of the heart rate (HR) variability from short and long-term electrocardiographic (ECG) recordings is a non-invasive method, which can used be as a tool to evaluate cardiac autonomic regulation. HR variability can give information about the sympathetic-parasympathetic autonomic balance. One important clinical application is to measure HR variability from patients suffering acute myocardial infarction (AMI). However, HR variability signals, R-R interval time series obtained from ambulatory ECG recordings contain in most of the cases different amount of artefacts. Artefacts appear due to disturbances of either physiological or technical origin. For instance, technical artefacts may result from poorly fastened electrodes or be due to motion artefacts. Ectopic beats and atrial fibrillation are examples of biological artefacts. Since the ectopic beats and other artifacts are common phenomena in the R-R interval time series, they make a reliable analysis of the HR variability difficult or even impossible. In conjunction with the increased usage of HR variability analyses, various studies have confirmed the need of different approaches to handle artefacts in the R-R interval time series. The editing process of the R-R interval time series has become an important part of the HR variability analysis. Several different editing and HR variability signal preprocessing methods have been introduced and tested for the artefact correction. Artifact correction can be performed with different methods such as deletion, various interpolation methods and different filtering systems. However, different editing methods can have different effects on the HR variability measures. The effects of editing is depended on the study setting including the editing method, HR variability measure, type of study population, length of the R-R interval time series.

220 citations


Cites background or methods from "A Real-Time QRS Detection Algorithm..."

  • ..., 2001) or some other digital filtering methods (Pan and Tompkins, 1985; Hamilton and Tompkins, 1986; Israel et al., 2005; Arzeno et al., 2008), pattern recognition (Mehta et al....

    [...]

  • ...…can be detected with different algorithms based for example on Hilbert transform (Benitez et al., 2001) or some other digital filtering methods (Pan and Tompkins, 1985; Hamilton and Tompkins, 1986; Israel et al., 2005; Arzeno et al., 2008), pattern recognition (Mehta et al., 1996), and wavelet…...

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Journal ArticleDOI
TL;DR: An automatic multiclass arousal/valence classifier is implemented comparing performance when extracted features from nonlinear methods are used as an alternative to standard features and results show that, when nonlinearly extracted features are used, the percentages of successful recognition dramatically increase.
Abstract: This paper reports on a new methodology for the automatic assessment of emotional responses. More specifically, emotions are elicited in agreement with a bidimensional spatial localization of affective states, that is, arousal and valence dimensions. A dedicated experimental protocol was designed and realized where specific affective states are suitably induced while three peripheral physiological signals, i.e., ElectroCardioGram (ECG), ElectroDermal Response (EDR), and ReSPiration activity (RSP), are simultaneously acquired. A group of 35 volunteers was presented with sets of images gathered from the International Affective Picture System (IAPS) having five levels of arousal and five levels of valence, including a neutral reference level in both. Standard methods as well as nonlinear dynamic techniques were used to extract sets of features from the collected signals. The goal of this paper is to implement an automatic multiclass arousal/valence classifier comparing performance when extracted features from nonlinear methods are used as an alternative to standard features. Results show that, when nonlinearly extracted features are used, the percentages of successful recognition dramatically increase. A good recognition accuracy (>;90 percent) after 40-fold cross-validation steps for both arousal and valence classes was achieved by using the Quadratic Discriminant Classifier (QDC).

216 citations


Cites background from "A Real-Time QRS Detection Algorithm..."

  • ...HRV refers to the variation of the time interval between consecutive heartbeats....

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References
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Journal ArticleDOI
TL;DR: This review asserts that most one-channel QRS detectors described in the literature can be considered as having the same basic structure and a discussion of some of the current detection schemes is presented.
Abstract: The QRS detection algorithm is an essential part of any computer-based system for the analysis of ambulatory ECG recordings. This review asserts that most one-channel QRS detectors described in the literature can be considered as having the same basic structure. A discussion of some of the current detection schemes is presented with regard to this structure. Some additional features of QRS detectors are mentioned. The evaluation of performance and the problem of multichannel detection, which is now gaining importance, are also briefly treated.

254 citations

Journal ArticleDOI
TL;DR: The problem of detecting the QRS complex in the presence of noise was analysed and an optimised threshold criterion based on FP/FN was developed.
Abstract: The problem of detecting the QRS complex in the presence of noise was analysed. Most QRS detectors contain a filter to improve the signal-to-noise ratio and compare the signal with a threshold. In an earlier paper we identified an optimal filter. Various techniques to generate threshold and detector designs were studied. Automatic gain-control circuits with a fixed threshold have a very slow response to different rhythms. Automatic threshold circuits based on simple peak-detection schemes have a fast response, but are very sensitive to sudden variations in QRS amplitudes and noise transients. None of the methods described to date present any optimisation criteria for detecting the signal (QRS complex) in the presence of noise. The probabilities of FPs (false positives) and FNs (false negatives) were investigated and an optimised threshold criterion based on FP/FN was developed. Presently, data are being collected to compare various techniques from their ROC (receiver operating characteristics).

151 citations

Journal ArticleDOI
TL;DR: An automated Holtes scanning system based on two microcomputers that detects QRS complexes and measures the QRS durations using computations of first and second derivatives, and can process Holter tapes at 60 times real time and produce printed summaries and 24 h trend plots.
Abstract: We have developed an automated Holtes scanning system based on two microcomputers. One is a preprocessor that detects QRS complexes and measures the QRS durations using computations of first and second derivatives. Thismicrocomputer interfaces to a secondmicro-computer that does arrhythmia analysis, logging, and reporting using R-R intervals and QRS durations. This system can process Holter tapes at 60 times real time and produce printed summaries and 24 h trend plots of several variables including heart rate and PVC count.

127 citations


"A Real-Time QRS Detection Algorithm..." refers methods in this paper

  • ...The slope of the R wave is a popular signal feature used to locate the QRS complex in many QRS detectors [5]....

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Journal ArticleDOI
P. A. Lynn1
TL;DR: The possibilities for extending the class of lowpass recursive digital filters to include high pass, bandpass, and bandstop filters are described, and experience with a PDP 11 computer has shown that these filters may be programmed simply using machine code, and that online operation at sampling rates up to about 8 kHz is possible.
Abstract: After reviewing the design of a class of lowpass recursive digital filters having integer multiplier and linear phase characteristics, the possibilities for extending the class to include high pass, bandpass, and bandstop (‘notch’) filters are described. Experience with a PDP 11 computer has shown that these filters may be programmed simply using machine code, and that online operation at sampling rates up to about 8 kHz is possible. The practical application of such filters is illustrated by using a notch desgin to remove mains-frequency interference from an e.c.g. waveform.

104 citations

Journal ArticleDOI
TL;DR: In this paper a new robust single lead QRS-detection algorithm is presented, allowing real-time applications and results are presented.

101 citations