A reinvestigation of inhibitors of glyoxalase I
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"A reinvestigation of inhibitors of ..." refers methods in this paper
...Protein was estimated by the method of either Warburg and Christian or that of Lowry et al. as described by Layne (1957)....
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1,373 citations
"A reinvestigation of inhibitors of ..." refers methods in this paper
...Glyoxalase I was assayed by monitoring the formation of S-D-lactoylglutathione, which was measured by its absorbance at 240 nm or colorimetrically by the hydroxylamine-ferric chloride colour reaction method (Lipmann and Tuttle, 1945) as used for the assay of thioesters (Racker, 1952)....
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538 citations
"A reinvestigation of inhibitors of ..." refers background in this paper
...The glyoxalase system consists of two enzymes, glyoxalase Ι (EC 4·4·1·5) and glyoxalase II (EC 3· 1·2·6) (Racker, 1951), Glyoxalase I acts upon GSH and methylglyoxal (and other á6-ketoaldehydes) to produce S-D-lactoylglutathione....
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118 citations
"A reinvestigation of inhibitors of ..." refers background in this paper
...The enzymes responsible for the formation of methylglyoxal have been purified from several sources (Hopper and Cooper, 1972; Ray and Ray, 1981, 1983, 1987; Murata et al., 1985)....
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105 citations
"A reinvestigation of inhibitors of ..." refers background or methods or result in this paper
...However the S-alkyl glutathiones served as controls and appeared to be true inhibitors of glyoxalase I as reported earlier (Vince and Wadd, 1969)....
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...S-Alkyl glutathiones were also found to be strong competitive inhibitors of glyoxalase I (Vince and Wadd, 1969; Vince et al., 1973; Lyon and Vince, 1977)....
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...Based on these assumptions GSH analogues have been synthesized and used as inhibitors of glyoxalase I (Vince and Wadd, 1969; Vince et al., 1973; Lyon and Vince, 1977)....
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