Journal ArticleDOI
A review of the clinical implications of anti-infective biomaterials and infection-resistant surfaces
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TLDR
The diversity and complexity of the different scenarios where medical devices are currently utilised are explored, providing an overview of the emblematic applicative fields and of the requirements for anti-infective biomaterials.About:
This article is published in Biomaterials.The article was published on 2013-11-01. It has received 281 citations till now.read more
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Implant infections: adhesion, biofilm formation and immune evasion
TL;DR: The fundamental pathogenic mechanisms underlying implant infections are explored, highlighting orthopaedic implants and Staphylococcus aureus as a prime example, and innovative targets for preventive and therapeutic strategies are discussed.
Journal ArticleDOI
Biofilm-Related Infections: Bridging the Gap between Clinical Management and Fundamental Aspects of Recalcitrance toward Antibiotics
TL;DR: This review presents the current understanding of the molecular mechanisms of biofilm recalcitrance toward antibiotics and describes how recent progress has improved the capacity to design original and efficient strategies to prevent or eradicate biofilm-related infections.
Journal ArticleDOI
Biofilms in the Food Industry: Health Aspects and Control Methods
Serena Galié,Coral García-Gutiérrez,Coral García-Gutiérrez,Elisa M. Miguélez,Elisa M. Miguélez,Claudio J. Villar,Claudio J. Villar,Felipe Lombó,Felipe Lombó +8 more
TL;DR: This review summarizes the current knowledge regarding the main bacterial species responsible for initial colonization, maturation and dispersal of food industry biofilms, as well as their associated health issues in dairy products, ready-to-eat foods and other food matrixes.
Journal ArticleDOI
Drug loaded homogeneous electrospun PCL/gelatin hybrid nanofiber structures for anti-infective tissue regeneration membranes
Jiajia Xue,Min He,Hao Liu,Yuzhao Niu,Aileen Crawford,P. D. Coates,Dafu Chen,Rui Shi,Liqun Zhang +8 more
TL;DR: The potential for using MNA-loaded PCL/gelatin electrospun membranes as anti-infective GTR/GBR membranes to optimize clinical application of GTR-GBR strategies is indicated.
Journal ArticleDOI
Antibacterial Surface Treatment for Orthopaedic Implants
TL;DR: There appears to be a great discrepancy between proposed and clinically implemented strategies, and there is urgent need for translational science focusing on this topic.
References
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Long-Term Use of a Left Ventricular Assist Device for End-Stage Heart Failure
Eric A. Rose,Annetine C. Gelijns,Alan J. Moskowitz,Daniel F. Heitjan,L.W. Stevenson,W Dembitsky,J W Long,D D Ascheim,Anita R. Tierney,R G Levitan,John T. Watson,P Meier,Nuala S. Ronan,P A Shapiro,Ronald M. Lazar,Leslie W. Miller,L Gupta,O.H. Frazier,Patrice Desvigne-Nickens,Mehmet C. Oz,V L Poirier +20 more
TL;DR: The use of a left ventricular assist device in patients with advanced heart failure resulted in a clinically meaningful survival benefit and an improved quality of life.
Journal ArticleDOI
On the mechanisms of biocompatibility.
TL;DR: It is shown that, in the vast majority of circumstances, the sole requirement for biocompatibility in a medical device intended for long-term contact with the tissues of the human body is that the material shall do no harm to those tissues, achieved through chemical and biological inertness.
Journal ArticleDOI
Treatment of infections associated with surgical implants.
TL;DR: This review summarizes the diagnostic challenges and explains the approaches to managing infections that are associated with various devices, including prosthetic heart valves, vascular grafts, pacemakers and defibrillators, and joint prostheses.
Journal ArticleDOI
Diagnosis, Prevention, and Treatment of Catheter-Associated Urinary Tract Infection in Adults: 2009 International Clinical Practice Guidelines from the Infectious Diseases Society of America
Thomas M. Hooton,Suzanne F. Bradley,Diana D. Cardenas,Richard Colgan,Suzanne E. Geerlings,James C. Rice,Sanjay Saint,Anthony J. Schaeffer,Paul A. Tambayh,Peter Tenke,Lindsay E. Nicolle +10 more
TL;DR: These guidelines are intended for use by physicians in all medical specialties who perform direct patient care, with an emphasis on the care of patients in hospitals and long-term care facilities.
Journal ArticleDOI
Epidemiology and Outcomes of Ventilator-Associated Pneumonia in a Large US Database
Jordi Rello,Daniel A. Ollendorf,Gerry Oster,Montserrat Vera-Llonch,Lisa A. Bellm,Rebecca Redman,Marin H. Kollef +6 more
TL;DR: It is demonstrated that VAP is a common nosocomial infection that is associated with poor clinical and economic outcomes and strategies to prevent the occurrence of VAP may not reduce mortality, but they may yield other important benefits to patients, their families, and hospital systems.