A role of dendrimers in drug delivery for cancer therapy
15 Feb 2021-pp 09-16
TL;DR: This review represents the advantages of Dendrimers over conventional chemotherapy, toxicity, and its management and recent advances in drug delivery by different types of Dendedrimers.
Abstract: In the history of nanotechnology, Dendrimers are rolling in as a highly tempting class of drug delivery system for cancer therapy. Dendrimers are the best and smart choice as Nanocarriers to deliver one or more therapeutic agents safely and selectively to cancer cells. Dendrimers that have remarkable properties including membrane interaction, monodispersity, well-defined size, shape and molecular weight, etc. Functional groups that are present in the Dendrimers exterior also permit other chemical moieties that can actively target certain diseases which are now widely used as tumor-targeting strategies. There are three ways by which drugs interact with dendrimers, (a) physical encapsulation, (b) electrostatic interactions, and (c) covalent conjugations. This review represents the advantages of Dendrimers over conventional chemotherapy, toxicity, and its management. The anti-cancer drugs are delivered by using Dendrimers and recent advances in drug delivery by different types of Dendrimers.
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TL;DR: In this paper , a review of various properties of the dendrimers, investigate the properties of their various types and discover the reasons for their employment in treatment of lung cancer, the novelty being brought in them and the alterations which make them a potential chemotherapeutic drug delivery system.
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TL;DR: In this article, the authors proposed a nanotheranostic platform for cancer diagnosis and treatment using a class of highly branched nanocarriers known as dendrimers.
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